A Newly Discovered Role for mRNA Methylation in Controlling Plant Gene Expression (PLANT-RNA-MET)

Research output

Research output per year 2020 2021 2022

• 5 Article

Research output per year

Research output per year

Search results

• 2022

  m⁶A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site

  Parker, M. T., Soanes, B. K., Kusakina, J., Larrieu, A., Knop, K., Joy, N., Breidenbach, F., Sherwood, A. V., Barton, G. J., Fica, S. M., Davies, B. H. & Simpson, G. G., 30 Dec 2022, In: eLife. 11, 34 p., e78808.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • U6 small nuclear RNA 100%
  • RNA Splice Sites 79%
  • RNA Precursors 71%
  • Modification 35%
  • U5 small nuclear RNA 32%
  8 Citations (Scopus)

  31 Downloads (Pure)
• 2021

  2passtools: two-pass alignment using machine-learning-filtered splice junctions increases the accuracy of intron detection in long-read RNA sequencing

  Parker, M. T., Knop, K., Barton, G. J. & Simpson, G. G., 1 Mar 2021, In: Genome Biology. 22, 1, 24 p., 72.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • artificial intelligence 100%
  • Machine Learning 95%
  • RNA Sequence Analysis 94%
  • RNA 87%
  • machine learning 84%
  9 Citations (Scopus)

  173 Downloads (Pure)

• Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site

  Mendes, V., Green, S. R., Evans, J. C., Hess, J., Blaszczyk, M., Spry, C., Bryant, O., Cory-Wright, J., Chan, D. S-H., Torres, P. H. M., Wang, Z., Nahiyaan, N., O'Neill, S., Damerow, S., Post, J., Bayliss, T., Lynch, S. L., Coyne, A. G., Ray, P. C., Abell, C., & 6 othersRhee, K. Y., Boshoff, H. I. M., Barry, C. E., Mizrahi, V., Wyatt, P. G. & Blundell, T. L., 8 Jan 2021, In: Nature Communications. 12, 12 p., 143.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • tuberculosis 100%
  • Allosteric Site 85%
  • Coenzyme A 74%
  • coenzymes 72%
  • Mycobacterium tuberculosis 58%
  8 Citations (Scopus)

  58 Downloads (Pure)

• Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA

  Parker, M., Knop, K., Zacharaki, V., Sherwood, A., Tomé, D., Yu, X., Martin, P., Beynon, J., Michaels, S., Barton, G. J. & Simpson, G. G., 12 May 2021, In: eLife. 10, 36 p., e65537.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Arabidopsis 100%
  • Leucine 78%
  • RNA Sequencing 63%
  • Nucleotides 61%
  • Disease Resistance 51%
  27 Citations (Scopus)

  161 Downloads (Pure)
• 2020

  Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification

  Parker, M. T., Knop, K., Sherwood, A. V., Schurch, N. J., Mackinnon, K., Gould, P. D., Hall, A. J. W., Barton, G. J. & Simpson, G. G., 14 Jan 2020, In: eLife. 9, 35 p., e49658.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • RNA Sequencing 100%
  • Nanopores 92%
  • Arabidopsis 78%
  • RNA Sequence Analysis 67%
  • Messenger RNA 34%
  232 Citations (Scopus)

  124 Downloads (Pure)