Research output per year
Research output per year
Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 1/01/13 → 30/09/15 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Datasets
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PROTAC-mediated complex of KRAS with VHL/Elongin-B/Elongin-C/Cullin-2/Rbx1
Fischer, G. (Creator), Peter, D. (Creator), Arce-Solano, S. (Creator) & Ciulli, A. (Creator), Research Collaboratory for Structural Bioinformatics Protein Data Bank, 6 Dec 2023
DOI: 10.2210/pdb8qu8/pdb
Dataset
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BindingDB Entry 50008275: Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.
BindingDB, Thomas, M. (Creator), De Rycker, M. (Creator), Ajakane, M. (Creator), Albrecht, S. (Creator), Álvarez-Pedraglio, A. I. (Creator), Boesche, M. (Creator), Brand, S. (Creator), Campbell, L. (Creator), Cantizani-Perez, J. (Creator), Cleghorn, L. (Creator), Copley, R. C. B. (Creator), Crouch, S. D. (Creator), Daugan, A. (Creator), Drewes, G. (Creator), Ferrer-Bazaga, S. (Creator), Ghidelli-Disse, S. (Creator), Gonzalez, S. (Creator), Gresham, S. L. (Creator), Hill, A. P. (Creator), Hindley, S. J. (Creator), Lowe, R. M. (Creator), Mackenzie, C. (Creator), MacLean, L. (Creator), Manthri, S. (Creator), Martin, F. (Creator), Miguel-Siles, J. (Creator), Norval, S. (Creator), Osuna-Cabello, M. (Creator), Woodland, A. (Creator), Patterson, S. (Creator), Pena, I. (Creator), Quesada-Campos, M. T. (Creator), Reid, I. H. (Creator), Revill, C. (Creator), Riley, J. (Creator), Ruiz-Gomez, J. R. (Creator), Shishikura, Y. (Creator), Simeons, F. (Creator), Smith, V. C. (Creator), Spinks, D. (Creator), Stojanovski, L. (Creator), Thomas, J. (Creator), Thompson, S. (Creator), Underwood, T. Z. (Creator), Gray, D. (Creator), Fiandor, J. M. (Creator), Gilbert, I. (Creator), Wyatt, P. (Creator), Read, K. (Creator) & Miles, T. J. (Creator), BindingDB, 22 Feb 2021
DOI: 10.7270/q2zc867r
Dataset
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BindingDB Entry 50018902: Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.
BindingDB, Brand, S. (Creator), Ko, E. J. (Creator), Viayna Gaza, E. (Creator), Thompson, S. (Creator), Spinks, D. (Creator), Thomas, M. (Creator), Sandberg, L. (Creator), Francisco, A. F. (Creator), Jayawardhana, S. (Creator), Smith, V. (Creator), Jansen, C. (Creator), De Rycker, M. (Creator), Thomas, J. (Creator), MacLean, L. (Creator), Osuna-Cabello, M. (Creator), Riley, J. (Creator), Scullion, P. (Creator), Stojanovski, L. (Creator), Simeons, F. (Creator), Epemolu, O. (Creator), Shishikura, Y. (Creator), Crouch, S. D. (Creator), Bakshi, T. S. (Creator), Nixon, C. J. (Creator), Reid, I. H. (Creator), Hill, A. P. (Creator), Underwood, T. Z. (Creator), Hindley, S. J. (Creator), Robinson, S. (Creator), Kelly, J. M. (Creator), Fiandor, J. M. (Creator), Wyatt, P. (Creator), Marco, M. (Creator), Miles, T. J. (Creator), Read, K. (Creator) & Gilbert, I. (Creator), BindingDB, 22 Apr 2024
DOI: 10.7270/q2zw1r50
Dataset
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Scalable insect cell expression and purification screening applied to CRL4-DCAF substrate receptors
Cowan, A. D. (Lead / Corresponding author), Jaekel, S. & Ciulli, A. (Lead / Corresponding author), Jul 2026, In: Protein Expression and Purification. 241, 11 p., 106907.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Downloads (Pure) -
Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes
Ma, N., Bhattacharya, S., Muk, S., Jandova, Z., Schmalhorst, P. S., Ghosh, S., Le, K., Diers, E., Trainor, N., Farnaby, W., Roy, M. J., Kofink, C., Greb, P., Weinstabl, H., Ciulli, A., Bader, G., Sankar, K., Bergner, A. (Lead / Corresponding author) & Vaidehi, N., Dec 2025, In: Nature Communications. 16, 1, 8595.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Link opens in a new tab Citations (Scopus)57 Downloads (Pure) -
Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-loaded KRAS(on) Alleles
Vetma, V., Puoti, I., Karolak, N. K., Chakraborti, S., Diers, E., Girardi, E., Khan, S., Kidd, G., Kropatsch, K. G., Mclennan, R., O'Connor, S., Samwer, M., Trainor, N., Whitworth, C., Wijaya, A. J., Wong, J. Y. F., Zollman, D., Farnaby, W., Popow, J. & Ciulli, A. (Lead / Corresponding author) & 2 others, , 12 Nov 2025, In: Journal of the American Chemical Society. 147, 45, p. 41367-41378 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)58 Downloads (Pure)