AMP-Activated Protein Kinase - A Tumour Suppressor that Opposes the Metabolic Changes in Proliferating Cells (Programme Grant)

Project Details

Effective start/end date1/01/1330/09/18


  • Cancer Research UK (C37030/A15101): £297,818.49
  • Cancer Research UK (C37030/A15101): £520,473.00

Research Output

  • 2 Chapter (peer-reviewed)
  • 2 Article
  • 1 Review article

AMP-Activated Protein Kinase: Friend or Foe in Cancer

Vara-ciruelos, D., Dandapani, M. & Hardie, D. G., 4 Mar 2020, In : Annual Review of Cancer Biology. 4, p. 1-16 16 p.

Research output: Contribution to journalReview article

Open Access
  • 22 Downloads (Pure)

    Phenformin, but not metformin, delays development of T-cell acute lymphoblastic leukemia/lymphoma via cell-autonomous AMPK activation

    Vara Ciruelos, D., Dandapani, M., Russell, F. M., Grzes, K., Atrih, A., Foretz, M., Viollet, B., Lamont, D. J., Cantrell, D. A. & Hardie, D. G., 16 Apr 2019, In : Cell Reports. 27, 3, p. 690-698.e4 15 p.

    Research output: Contribution to journalArticle

    Open Access
  • 12 Citations (Scopus)
    126 Downloads (Pure)

    Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK

    Fyffe, F. A., Hawley, S. A., Gray, A. & Hardie, D. G., 2018, AMPK : Methods and Protocols. Neumann, D. & Viollet, B. (eds.). New York: Humana Press, p. 69-86 18 p. (Methods in Molecular Biology; vol. 1732).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  • 3 Citations (Scopus)