AMP-Activated Protein Kinase - A Tumour Suppressor that Opposes the Metabolic Changes in Proliferating Cells (Programme Grant)

Hardie, Grahame (Investigator)

Cell Signalling and Immunology

Research Output

2 Chapter (peer-reviewed)
2 Article
1 Review article

2 results

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2019

Phenformin, but not metformin, delays development of T-cell acute lymphoblastic leukemia/lymphoma via cell-autonomous AMPK activation

Vara Ciruelos, D., Dandapani, M., Russell, F. M., Grzes, K., Atrih, A., Foretz, M., Viollet, B., Lamont, D. J., Cantrell, D. A. & Hardie, D. G., 16 Apr 2019, In : Cell Reports. 27, 3, p. 690-698.e4 15 p.

Research output: Contribution to journal › Article

Open Access

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13 Citations (Scopus)

127 Downloads (Pure)

2018

Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival

Vara Ciruelos, D., Dandapani, M., Gray, A., Agbani, E. O., Evans, A. M. & Hardie, D. G., Feb 2018, In : Molecular Cancer Research. 16, 2, p. 345-357 13 p.

Research output: Contribution to journal › Article

Open Access

File

18 Citations (Scopus)

139 Downloads (Pure)