Aref#d: 19770. Division of Gene Regulation and Expression Strategic Award

Search results

• 2017

  Mechanisms mitigating problems with multiple kinetochores on one microtubule in early mitosis

  Yue, Z., Komoto, S., Gierlinski, M., Pasquali, D., Kitamura, E. & Tanaka, T. U. (Lead / Corresponding author), 15 Jul 2017, In: Journal of Cell Science. 130, 14, p. 2266-2276 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mitosis 100%
  • Kinetochore 100%
  • Microtubules 100%
  • Microtubule 100%
  • Budding Yeast 100%

  2   Link opens in a new tab Citations (Scopus)

  197 Downloads (Pure)

• Molecular mechanisms facilitating the initial kinetochore encounter with spindle microtubules

  Vasileva, V., Gierlinski, M., Yue, Z., O'Reilly, N., Kitamura, E. & Tanaka, T. U. (Lead / Corresponding author), 26 Apr 2017, In: Journal of Cell Biology. 216, 6, p. 1809-1822 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Molecular Mechanism 100%
  • Kinetochore 100%
  • Spindle Microtubules 100%
  • Microtubule 100%
  • Budding Yeast 100%

  14   Link opens in a new tab Citations (Scopus)

  507 Downloads (Pure)

• 2015

  Kinetochore-microtubule error correction is driven by differentially regulated interaction modes

  Kalantzaki, M., Kitamura, E., Zhang, T., Mino, A., Novák , B. & Tanaka, T. U. (Lead / Corresponding author), Apr 2015, In: Nature Cell Biology. 17, 4, p. 421-433 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Error Correction 100%
  • Biorientation 100%
  • Interaction Mode 100%
  • Kinetochore Microtubules 100%
  • Regulated Interactions 100%

  53   Link opens in a new tab Citations (Scopus)

  614 Downloads (Pure)

• 2013

  High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination

  Hawkins, M., Retkute, R., Müller, C. A., Saner, N., Tanaka, T. U., deMoura, A. P. S. & Nieduszynski, C. A. (Lead / Corresponding author), 27 Nov 2013, In: Cell Reports. 5, 4, p. 1132-1141 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • High-resolution 100%
  • Genome Replication 100%
  • Replication Initiation 100%
  • Stochastic Nature 100%
  • Replication Termination 100%

  63   Link opens in a new tab Citations (Scopus)

  107 Downloads (Pure)

• Identification and functional characterization of FMN2: a regulator of the cyclin-dependent kinase Inhibitor p21

  Yamada, K., Ono, M., Perkins, N. D., Rocha, S. (Lead / Corresponding author) & Lamond, A. I. (Lead / Corresponding author), Mar 2013, In: Molecular Cell. 49, 5, p. 922-933 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclin-dependent Kinase Inhibitor p21 100%
  • Functional Characterization 100%
  • Formin 2 100%
  • Cyclin-Dependent Kinase 100%
  • P21 100%

  46   Link opens in a new tab Citations (Scopus)

• Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment

  Natsume, T., Müller, C. A., Katou, Y., Retkute, R., Gierlinski, M., Araki, H., Blow, J. J., Shirahige, K., Nieduszynski, C. A. & Tanaka, T. U. (Lead / Corresponding author), 6 Jun 2013, In: Molecular Cell. 50, 5, p. 661-674 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Kinetochore 100%
  • Cohesion 100%
  • DNA Replication 100%
  • Sigma Phase 100%
  • Cell Division Cycle 7 (Cdc7) 100%

  123   Link opens in a new tab Citations (Scopus)

• Stochastic association of neighboring replicons creates replication factories in budding yeast

  Saner, N., Karschau, J., Natsume, T., Gierlinski, M., Retkute, R., Hawkins, M., Nieduszynski, C. A., Blow, J. J., de Moura, A. P. S. & Tanaka, T. U., 2013, In: Journal of Cell Biology. 202, 7, p. 1001-1012 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Budding Yeast 100%
  • Replication Factory 100%
  • Replicon 100%
  • Stochastic Association 100%
  • Replication Protein 16%

  44   Link opens in a new tab Citations (Scopus)

• The amidation step of Diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network

  Uthman, S., Baer, C., Scheidt, V., Liu, S., Ten Have, S., Giorgini, F., Stark, M. J. R. & Schaffrath, R., 2013, In: PLoS Genetics. 9, 2, e1003334.

  Research output: Contribution to journal › Article › peer-review

  • Interaction Network 100%
  • Diphthamide 100%
  • Amidation 100%
  • DPH1 100%
  • Anabolism 100%

  51   Link opens in a new tab Citations (Scopus)

• The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

  Bett, J. S., Ibrahim, A. F. M., Garg, A. K., Kelly, V., Pedrioli, P., Rocha, S. & Hay, R. T., 15 Apr 2013, In: Biochemical Journal. 451, 2, p. 185-194 10 p., BJ20130026.

  Research output: Contribution to journal › Article › peer-review

  • Body Components 100%
  • Novel Regulator 100%
  • Hypoxia-inducible factor-1α (HIF-1α) 100%
  • Ubiquitin-specific Protease 100%
  • MRNA Stability 100%

  53   Link opens in a new tab Citations (Scopus)

• Three wise centromere functions: see no error, hear no break, speak no delay

  Tanaka, T. U., Clayton, L. & Natsume, T., Dec 2013, In: EMBO Reports. 14, 12, p. 1073-1083 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Centromere 100%
  • Kinetochore 60%
  • Microtubule Attachment 40%
  • Mitosis 20%
  • Chromosome Segregation 20%

  20   Link opens in a new tab Citations (Scopus)

• 2012

  Chromatin as an oxygen sensor and active player in the hypoxia response

  Melvin, A. & Rocha, S., Jan 2012, In: Cellular Signalling. 24, 1, p. 35-43 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Chromatin 100%
  • Hypoxia-inducible Factor 100%
  • Hypoxia Response 100%
  • Oxygen Sensor 100%
  • Hypoxia-Inducible Factors 100%

  106   Link opens in a new tab Citations (Scopus)

• Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

  Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J., 21 Sept 2012, In: Journal of Biological Chemistry. 287, 39, p. 32346-53 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclin D1 (CCND1) 100%
  • Histone Deacetylase 1 (HDAC1) 100%
  • SIN3 100%
  • FAM60A 100%
  • Cell Cycle 100%

  34   Link opens in a new tab Citations (Scopus)

• hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies

  Drakou, C. E., Malekkou, A., Hayes, J. M., Lederer, C. W., Leonidas, D. D., Oikonomakos, N. G., Lamond, A. I., Santama, N. & Zographos, S. E., Jan 2012, In: Proteins: Structure, Function, and Bioinformatics. 80, 1, p. 206-220 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Coilin 100%
  • ATP Synthase 100%
  • Functional Studies 100%
  • Adenylate Kinase 100%
  • ATPase 100%

  25   Link opens in a new tab Citations (Scopus)

• Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins

  Gillespie, P. J., Gambus, A. & Blow, J. J., Jun 2012, In: Methods. 57, 2, p. 203-13 11 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Replication 100%
  • Replication Protein A 100%
  • Xenopus Egg Extract 100%
  • Chromatin-associated Proteins 100%
  • DNA Synthesis 100%

  61   Link opens in a new tab Citations (Scopus)

• 2011

  Antagonistic crosstalk between APC and HIF-1 alpha

  Nathke, I. & Rocha, S., 15 May 2011, In: Cell Cycle. 10, 10, p. 1545-1547 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Beta-Catenin 100%
  • Hypoxia-inducible factor-1α (HIF-1α) 100%
  • Antigen-Presenting Cell 100%
  • Hypoxia 60%
  • Protein Complexes 50%

  17   Link opens in a new tab Citations (Scopus)

• Evolutionary conserved regulation of HIF-1 beta by NF-kappa B

  van Uden, P., Kenneth, N. S., Webster, R., Muller, H. A., Mudie, S. & Rocha, S. (Lead / Corresponding author), Jan 2011, In: PLoS Genetics. 7, 1, p. - 15 p., e1001285.

  Research output: Contribution to journal › Article › peer-review

  • Evolutionary 100%
  • Nuclear factor-κB 100%
  • Hypoxia-inducible factor-1α (HIF-1α) 100%
  • Immunoglobulin Enhancer Binding Protein 100%
  • Aryl Hydrocarbon Receptor Nuclear Translocator 100%

  148   Link opens in a new tab Citations (Scopus)

• Exo70, a subunit of the exocyst complex, interacts with SNEVhPrp19/hPso4 and is involved in pre-mRNA splicing

  Dellago, H., Löscher , M., Ajuh, P., Ryder, U., Kaisermayer, C., Grillari-Voglauer, R., Fortschegger, K., Gross, S., Gstraunthaler, A., Borth, N., Eisenhaber, F., Lamond, A. I. & Grillari, J., 15 Aug 2011, In: Biochemical Journal. 438, p. 81-91 11 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Splicing 100%
  • Exocyst 100%
  • Exo70 100%
  • DNA Repair 66%
  • Cell Aging 66%

  22   Link opens in a new tab Citations (Scopus)

• HIF-1 alpha depletion results in SP1-mediated cell cycle disruption and alters the cellular response to chemotherapeutic drugs

  Culver, C., Melvin, A., Mudie, S. & Rocha, S., 15 Apr 2011, In: Cell Cycle. 10, 8, p. 1249-1260 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cellular Response 100%
  • Hypoxia-inducible factor-1α (HIF-1α) 100%
  • SP-1 100%
  • Cell Cycle 100%
  • Hypoxia Inducible Factor 1 100%

  34   Link opens in a new tab Citations (Scopus)

• Identification of human miRNA precursors that resemble box C/D snoRNAs

  Ono, M., Scott, M. S., Yamada, K., Avolio, F., Barton, G. J. & Lamond, A. I., May 2011, In: Nucleic Acids Research. 39, 9, p. 3879-3891 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Small nucleolar RNA (snoRNA) 100%
  • MiRNA Precursor 100%
  • Precursor 100%
  • MicroRNA 100%
  • Small Nucleolar RNA 100%

  121   Link opens in a new tab Citations (Scopus)

• Mass spectrometry-based immuno-precipitation proteomics - The user's guide

  ten Have, S., Boulon, S., Ahmad, Y. & Lamond, A. I., Mar 2011, In: Proteomics. 11, 6, p. 1153-1159 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass Spectrometry 100%
  • Proteomics 100%
  • Co-immunoprecipitation (co-IP) 100%
  • User Guide 100%
  • Immunoprecipitation 100%

  74   Link opens in a new tab Citations (Scopus)

• Stable-isotope labeling with amino acids in nematodes

  Larance, M., Bailly, A. P., Pourkarimi, E., Hay, R. T., Buchanan, G., Coulthurst, S., Xirodimas, D. P., Gartner, A. (Lead / Corresponding author) & Lamond, A. I. (Lead / Corresponding author), Oct 2011, In: Nature Methods. 8, 10, p. 849-851 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Nematodes 100%
  • Amino Acids 100%
  • Worm 100%
  • Arginine 100%
  • Stable Isotope Labeling 100%

  100   Link opens in a new tab Citations (Scopus)

• The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH

  Melvin, A., Mudie, S. & Rocha, S., 1 Nov 2011, In: Molecular Biology of the Cell. 22, 21, p. 4171-4181 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cellular Response 100%
  • Chromatin Remodeling 100%
  • Hypoxia Response 100%
  • Factor Inhibiting HIF 100%
  • Imitation Switch 100%

  33   Link opens in a new tab Citations (Scopus)

• The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration

  Msaki, A., Sanchez, A. M., Koh, L. F., Barre, B., Rocha, S., Perkins, N. D. & Johnson, R. F., 1 Sept 2011, In: Molecular Biology of the Cell. 22, 17, p. 3032-3040 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cell Migration 100%
  • Cell Growth 100%
  • Phosphorylation 100%
  • Threonine 100%
  • Cell Survival 100%

  36   Link opens in a new tab Citations (Scopus)

  213 Downloads (Pure)

• 2010

  Adenomatous polyposis coli and hypoxia-inducible factor-1 alpha have an antagonistic connection

  Newton, I. P., Kenneth, N. S., Appleton, P. L., Nathke, I. & Rocha, S., 1 Nov 2010, In: Molecular Biology of the Cell. 21, 21, p. 3630-3638 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenomatous Polyposis Coli 100%
  • Hypoxia-inducible factor-1α (HIF-1α) 100%
  • Hypoxia Inducible Factor 1 100%
  • Hypoxia 40%
  • Beta-catenin 20%

  46   Link opens in a new tab Citations (Scopus)

• Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2

  MacKay, C., Declais, A.-C., Lundin, C., Agostinho, A., Deans, A. J., MacArtney, T. J., Hofmann, K., Gartner, A., West, S. C., Helleday, T., Lilley, D. M. J. & Rouse, J. (Lead / Corresponding author), 9 Jul 2010, In: Cell. 142, 1, p. 65-76 12 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Damage 100%
  • DNA Repair 100%
  • Nuclease 100%
  • FANCD2 100%
  • FAN1 100%

  261   Link opens in a new tab Citations (Scopus)

• Live-cell imaging RNAi screen identifies PP2A-B55 alpha and importin-beta 1 as key mitotic exit regulators in human cells

  Schmitz, M. H. A., Held, M., Janssens, V., Hutchins, J. R. A., Hudecz, O., Ivanova, E., Goris, J., Trinkle-Mulcahy, L., Lamond, A. I., Poser, I., Hyman, A. A., Mechtler, K., Peters, J.-M. & Gerlich, D. W., Sept 2010, In: Nature Cell Biology. 12, 9, p. 886-893 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Human Cells 100%
  • Live Cell Imaging 100%
  • Importin α 100%
  • Mitotic Exit 100%
  • PP2A-B55 100%

  280   Link opens in a new tab Citations (Scopus)

• Mechanism of Hypoxia-Induced NF-kappa B

  Culver, C., Sundqvist, A., Mudie, S., Melvin, A., Xirodimas, D. & Rocha, S. (Lead / Corresponding author), 10 Oct 2010, In: Molecular and Cellular Biology. 30, 20, p. 4901-4921 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypoxia 100%
  • Nuclear factor-κB 100%
  • Kappa B 100%
  • Immunoglobulin Enhancer Binding Protein 100%
  • Phosphotransferase 100%

  202   Link opens in a new tab Citations (Scopus)

• Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis

  Posch, M., Khoudoli, G. A., Swift, S., King, E. M., DeLuca, J. G. & Swedlow, J. R. (Lead / Corresponding author), 4 Oct 2010, In: Journal of Cell Biology. 191, 1, p. 61-74 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mitosis 100%
  • Aurora B 100%
  • Kinetochore 100%
  • Microtubules 100%
  • Phosphoprotein Phosphatase 1 100%

  106   Link opens in a new tab Citations (Scopus)

  425 Downloads (Pure)

• The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition

  Malekkou, A., Lederer, C. W., Lamond, A. I. & Santama, N., 19 Nov 2010, In: FEBS Letters. 584, 22, p. 4559-4564 6 p.

  Research output: Contribution to journal › Article › peer-review

  • ATP Synthase 100%
  • Adenylate Kinase 100%
  • HCINAP 100%
  • RNA 100%
  • Cajal Body 100%

  5   Link opens in a new tab Citations (Scopus)

• 2009

  Cell fate decisions are specified by the dynamic ERK interactome

  von Kriegsheim, A., Baiocchi, D., Birtwistle, M., Sumpton, D., Bienvenut, W., Morrice, N., Yamada, K., Lamond, A., Kalna, G., Orton, R., Gilbert, D. & Kolch, W., Dec 2009, In: Nature Cell Biology. 11, 12, p. 1458-1464 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Fate Decision 100%
  • Extracellular Signal-regulated Kinase 100%
  • Interactome 100%
  • Extracellular Signal-Regulated Kinases 100%
  • Cell Fate 100%

  252   Link opens in a new tab Citations (Scopus)

• Efficient chromosome biorientation and the tension checkpoint in saccharomyces cerevisiae both require Bir1

  Makrantoni, V. & Stark, M. J. R., 15 Aug 2009, In: Molecular and Cellular Biology. 29, 16, p. 4552-4562 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Saccharomyces Cerevisiae 100%
  • Chromosome Biorientation 100%
  • BIR1 100%
  • Saccharomyces cerevisiae 100%
  • Biorientation 100%

  17   Link opens in a new tab Citations (Scopus)

• Ipl1-dependent phosphorylation of Dam1 is reduced by tension applied on kinetochores

  Keating, P., Rachidi, N., Tanaka, T. U. & Stark, M. J. R., 1 Dec 2009, In: Journal of Cell Science. 122, 23, p. 4375-4382 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Kinetochore 100%
  • Phosphorylation 100%
  • Ipl1 100%
  • Dam1 100%
  • Aurora B 75%

  55   Link opens in a new tab Citations (Scopus)

• Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation

  Greiss, S. & Gartner, A., Nov 2009, In: Molecules and Cells. 28, 5, p. 407-415 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Phylogeny 100%
  • Sirtuins 100%
  • Structural Conservation 100%
  • Sir2 100%
  • Evolutionary Considerations 100%

  179   Link opens in a new tab Citations (Scopus)

• 2008

  In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy

  Matic, I., van Hagen, M., Schimmel, J., Macek, B., Ogg, S. C., Tatham, M. H., Hay, R. T., Lamond, A. I., Mann, M. (Lead / Corresponding author) & Vertegaal, A. C. O. (Lead / Corresponding author), 1 Jan 2008, In: Molecular & Cellular Proteomics. 7, 1, p. 132-144 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass Spectrometry 100%
  • Ubiquitin-like 100%
  • SUMO2 100%
  • Small Ubiquitin-like Modifier 100%
  • Ubiquitin 100%

  250   Link opens in a new tab Citations (Scopus)