Activities per year
Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 1/07/13 → 31/12/23 |
Funding
- Wellcome Trust (210753/Z/18/Z): £2,088,664.00
- Wellcome Trust (101022/Z/13/Z): £1,881,328.00
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Datasets
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Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity
De Cesare, V. (Creator), Zenodo, 18 Dec 2023
DOI: 10.5281/zenodo.10402851, https://zenodo.org/records/10402851
Dataset
Activities
- 1 Public engagement and outreach - public lecture/debate/seminar
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RSE Curious Festival: The quest to cure Parkinson's
Sammler, E. (Speaker), Muqit, M. (Speaker), Liu, X. (Speaker) & Hawdon, B. (Speaker)
15 Sept 2023Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain
Bagnoli, E., Lin, Y.-E., Burel, S., Jaimon, E., Antico, O., Themistokleous, C., Nikoloff, J. M., Squires, S., Morella, I., Watzlawik, J. O., Fiesel, F. C., Springer, W., Tonelli, F., Lis, P., Brooks, S. P., Dunnett, S. B., Brambilla, R., Alessi, D. R., Pfeffer, S. R. & Muqit, M. M. K. (Lead / Corresponding author), 4 Feb 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 5, 12 p., e2412029122.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)40 Downloads (Pure) -
Kinome screening identifies integrated stress response kinase EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signaling
Singh, P. K., Agarwal, S. (Lead / Corresponding author), Volpi, I., Wilhelm, L. P., Becchi, G., Keenlyside, A., Macartney, T., Toth, R., Rousseau, A., Masson, G. R., Ganley, I. G. & Muqit, M. M. K. (Lead / Corresponding author), 9 May 2025, In: Science Advances. 11, 19, 15 p., eadn2528.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans
Lenka, D. R., Dahe, S. V., Antico, O., Sahoo, P., Prescott, A. R., Muqit, M. M. K. & Kumar, A. (Lead / Corresponding author), 2 Sept 2024, (E-pub ahead of print) In: eLife. 13, 31 p., RP96699.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Downloads (Pure)