Biochemical Analysis of the PINK-1 Parkin Signalling Pathway in Parkinson's Disease (Senior Clinical Fellowship)

Muqit, Miratul (Investigator)

MRC PPU

Project Details

Status	Active
Effective start/end date	1/07/13 → 31/12/23

Funding

Wellcome Trust (210753/Z/18/Z): £2,088,664.00
Wellcome Trust (101022/Z/13/Z): £1,881,328.00

12 Article
1 Review article

Parkinson’s: A Disease of Aberrant Vesicle Trafficking
Singh, P. K. & Muqit, M. M. K., Oct 2020, In: Annual Review of Cell and Developmental Biology. 36, p. 237-264 28 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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4 Citations (Scopus)

10 Downloads (Pure)
PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2 mediated phosphorylation at Threonine72
Vieweg, S., Mulholland, K., Brauning, B., Kacharia, N., Lai, Y-C., Toth, R., Singh, P. K., Volpi, I., Sattler, M., Groll, M., Itzen, A. & Muqit, M. M. K., 11 May 2020, In: Biochemical Journal. 477, 9, p. 1651-1668 18 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
8 Citations (Scopus)

20 Downloads (Pure)
Are PARKIN patients ideal candidates for dopaminergic cell replacement therapies?
Kunath, T., Natalwala, A., Chan, C., Chen, Y., Stecher, B., Taylor, M., Khan, S. & Muqit, M. M. K., 25 Feb 2019, In: European Journal of Neuroscience. 49, 4, p. 453-462 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
6 Citations (Scopus)

122 Downloads (Pure)