Characterisation of the Ess Protein Secretion System of Staphylococcus Aureus a Key Virulence Factor

Research output

Research output per year 2016 2016 2017 2020

• 9 Article
• 1 Comment/debate
• 1 Review article

Research output per year

Research output per year

Search results

• 2020

  A membrane-depolarizing toxin substrate of the Staphylococcus aureus type VII secretion system mediates intraspecies competition

  Ulhuq, F. R., Gomes, M. C., Duggan, G. M., Guo, M., Mendonca, C., Buchanan, G., Chalmers, J. D., Cao, Z., Kneuper, H., Murdoch, S., Thomson, S., Strahl, H., Trost, M., Mostowy, S. & Palmer, T., 25 Aug 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 34, p. 20836-20847 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VII Secretion Systems 100%
  • Staphylococcus aureus 48%
  • Membranes 33%
  • Zebrafish 19%
  • Protein Translocation Systems 15%
  31 Citations (Scopus)

  95 Downloads (Pure)
• 2018

  EssC is a specificity determinant for Staphylococcus aureus type VII secretion

  Jäger, F., Kneuper, H. & Palmer, T., 1 May 2018, In: Microbiology. 164, 5, p. 816-820 5 p., 000650.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Staphylococcus aureus 100%
  • Type VII Secretion Systems 51%
  • Protein Translocation Systems 47%
  • Proteins 42%
  • Firmicutes 38%
  15 Citations (Scopus)

  164 Downloads (Pure)
• 2017

  Functional analysis of the EsaB component of the Staphylococcus aureus Type VII secretion system

  Casabona, M. G., Buchanan, G., Zoltner, M., Harkins, C. P., Holden, M. T. G. & Palmer, T., Dec 2017, In: Microbiology. 163, 12, p. 1851-1863 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VII Secretion Systems 100%
  • Staphylococcus aureus 48%
  • Ubiquitins 42%
  • Threonine 31%
  • Alanine 28%
  13 Citations (Scopus)

  213 Downloads (Pure)

• Haem-iron plays a key role in the regulation of the Ess/Type VII secretion system of Staphylococcus aureus RN6390

  Casabona, M. G., Kneuper, H., Alferes de Lima, D., Harkins, C. P., Zoltner, M., Hjerde, E., Holden, M. T. G. & Palmer, T., Dec 2017, In: Microbiology. 163, 12, p. 1839-1850 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VII Secretion Systems 100%
  • Hemin 76%
  • Heme 62%
  • Staphylococcus aureus 48%
  • Iron 47%
  8 Citations (Scopus)

  200 Downloads (Pure)

• Structural biology: Mycobacterial ESX secrets revealed

  Palmer, T., Jun 2017, In: Nature Microbiology. 2, 6, 17074.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File

  • Type VII Secretion Systems 100%
  • Virulence Factors 58%
  1 Citation (Scopus)

  254 Downloads (Pure)

• The Enigmatic Esx Proteins: Looking Beyond Mycobacteria

  Unnikrishnan, M., Constantinidou, C., Palmer, T. & Pallen, M. J., Mar 2017, In: Trends in Microbiology. 25, 3, p. 192-204 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Mycobacterium 100%
  • Bacteria 62%
  • Type VII Secretion Systems 54%
  • Proteins 34%
  • Eukaryota 31%
  71 Citations (Scopus)

  275 Downloads (Pure)
• 2016

  EssC: domain structures inform on the elusive translocation channels in the Type VII secretion system.

  Zoltner, M., Ng, W. M. A. V., Money, J. J., Fyfe, P. K., Kneuper, H., Palmer, T. & Hunter, W. N., Jul 2016, In: Biochemical Journal. 473, 13, p. 1941-1952 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VII Secretion Systems 100%
  • Adenosine Triphosphatases 56%
  • Geobacillus 32%
  • AAA Domain 27%
  • Observation 26%
  28 Citations (Scopus)

  190 Downloads (Pure)

• Membrane interactions and self-association of components of the Ess/Type VII secretion system of Staphylococcus aureus

  Jager, F., Zoltner, M., Kneuper, H., Hunter, W. N. & Palmer, T., 12 Feb 2016, In: FEBS Letters. 590, 3, p. 349-357 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VII Secretion Systems 100%
  • Self-Association 64%
  • Staphylococcus aureus 48%
  • Protein Translocation Systems 46%
  • Native Polyacrylamide Gel Electrophoresis 41%
  20 Citations (Scopus)

  160 Downloads (Pure)

• Spotlight on...Tracy Palmer

  Palmer, T., Dec 2016, In: FEMS Microbiology Letters. 363, 24, p. 1-3 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• The Ess/Type VII secretion system of Staphylococcus aureus shows unexpected genetic diversity

  Warne, B., Harkins, C. P., Harris, S. R., Vatsiou, A., Stanley-Wall, N., Parkhill, J., Peacock, S. J., Palmer, T. & Holden, M. T. G., 11 Mar 2016, In: BMC Genomics. 17, 13 p., 222.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VII Secretion Systems 100%
  • Genetic Variation 54%
  • Staphylococcus aureus 48%
  • Genetic Recombination 32%
  • Proteins 20%
  61 Citations (Scopus)

  195 Downloads (Pure)

• The type VII secretion system of Staphylococcus aureus secretes a nuclease toxin that targets competitor bacteria

  Cao, Z., Kneuper, H., Casabona, M. G., Chalmers, J. D. & Palmer, T., 10 Oct 2016, In: Nature Microbiology. 2, p. 1-11 11 p., 16183.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VII Secretion Systems 100%
  • Staphylococcus aureus 48%
  • Bacteria 38%
  • Protein Translocation Systems 30%
  • Poisons 28%
  140 Citations (Scopus)

  340 Downloads (Pure)