De-risking Innovative Drug Discovery Projects through Portfolio Management (Confidence in Concept)

Ferguson, Michael (Investigator)
Woodland, Andrew (Investigator)
Wyatt, Paul (Investigator)

Project Details

Status	Finished
Effective start/end date	1/03/14 → 31/08/15

Funding

Medical Research Council (MC_PC_13061): £800,000.00

3 Article

Screening of a novel fragment library with functional complexity against Mycobacterium tuberculosis InhA
Prati, F., Zuccotto, F., Fletcher, D., Convery, M. A., Fernandez-Menendez, R., Bates, R., Encinas, L., Zeng, J., Chung, C-W., De Dios Anton, P., Mendoza-Losana, A., Mackenzie, C., Green, S. R., Huggett, M., Barros, D., Wyatt, P. G. & Ray, P. C., 6 Apr 2018, In: ChemMedChem. 13, 7, p. 672-677 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Citations (Scopus)

135 Downloads (Pure)
Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem
Martins Da Silva, S. J., Brown, S. G., Sutton, K., King, L. V., Ruso, H., Gray, D. W., Wyatt, P. G., Kelly, M. C., Barratt, C. L. R. & Hope, A. G., May 2017, In: Human Reproduction. 32, 5, p. 974-984 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
10 Citations (Scopus)

140 Downloads (Pure)
Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM
Varshney, D., Petit, A-P., Bueren-Calabuig, J. A., Jansen, C., Fletcher, D. A., Peggie, M., Weidlich, S., Scullion, P., Pisliakov, A. V. & Cowling, V. H., 1 Dec 2016, In: Nucleic Acids Research. 44, 21, p. 10423-10436 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
19 Citations (Scopus)

338 Downloads (Pure)