De-Risking Innovative Drug Discovery Projects Through Portfolio Management

Ferguson, Michael (Investigator)
Wyatt, Paul (Investigator)

Project Details

Status	Finished
Effective start/end date	1/01/13 → 30/06/14

Funding

Medical Research Council (MC_PC_12013): £750,000.00

4 Article

Novel pharmacological actions of Trequinsin Hydrochloride improve human sperm cell motility and function
McBrinn, R. C., Fraser, J., Hope, A. G., Gray, D. W., Barratt, C. L. R., Martins da Silva, S. J. & Brown, S. G., Dec 2019, In: British Journal of Pharmacology. 176, 23, p. 4521-4536 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Citations (Scopus)

76 Downloads (Pure)
Screening of a novel fragment library with functional complexity against Mycobacterium tuberculosis InhA
Prati, F., Zuccotto, F., Fletcher, D., Convery, M. A., Fernandez-Menendez, R., Bates, R., Encinas, L., Zeng, J., Chung, C-W., De Dios Anton, P., Mendoza-Losana, A., Mackenzie, C., Green, S. R., Huggett, M., Barros, D., Wyatt, P. G. & Ray, P. C., 6 Apr 2018, In: ChemMedChem. 13, 7, p. 672-677 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Citations (Scopus)

165 Downloads (Pure)
Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem
Martins Da Silva, S. J., Brown, S. G., Sutton, K., King, L. V., Ruso, H., Gray, D. W., Wyatt, P. G., Kelly, M. C., Barratt, C. L. R. & Hope, A. G., May 2017, In: Human Reproduction. 32, 5, p. 974-984 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
9 Citations (Scopus)

180 Downloads (Pure)