Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 1/02/19 → 30/04/25 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Student theses
-
Cracking the Cryptosporidium Oocyst Wall Proteins
Bacchetti, R. (Author), Pawlowic, M. (Supervisor) & Horn, D. (Supervisor), 2023Student thesis: Doctoral Thesis › Doctor of Philosophy
-
Development of mode of action tools using lysyl-tRNA synthetase to support Cryptosporidium drug discovery
Hanna, J. C. (Author), Pawlowic, M. (Supervisor) & Wyllie, S. (Supervisor), 2023Student thesis: Doctoral Thesis › Doctor of Philosophy
File -
Exploiting chemical proteomic tools to identify mode of action of phenotypic hits in Cryptosporidium
Hall, G. (Author), Pawlowic, M. C. (Supervisor) & Wyllie, S. (Supervisor), 2026Student thesis: Doctoral Thesis › Doctor of Philosophy
-
Cryptosporidium Oocyst Wall Proteins are true components of the oocyst wall and COWP8 is not required for parasite transmission
Bacchetti, R., Stevens, S., Lemgruber, L., Oliva, M. A. G., Sands, E. M., Alexandrou, K., Tinti, M., Robinson, L., Hanna, J. C., Seizova, S., Goddard, P., Vassalli, M. & Pawlowic, M. C. (Lead / Corresponding author), 23 Oct 2025, In: PLoS Pathogens. 21, 10, 26 p., e1013561.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)14 Downloads (Pure) -
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy
Caldwell, N., Peet, C., Miller, P., Colon, B., Taylor, M., Cocco, M., Dawson, A., Lukac, I., Teixeira, J. E., Robinson, L., Frame, L., Seizova, S., Damerow, S., Tamaki, F., Post, J., Riley, J., Mutter, N., Hanna, J. C., Ferguson, L. & Hu, X. & 13 others, , 23 Oct 2024, In: Science Translational Medicine. 16, 770, p. 1-12 12 p., eadm8631.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Link opens in a new tab Citations (Scopus)339 Downloads (Pure) -
Cryptosporidium Oocyst Wall Proteins are true oocyst wall proteins, with COWP8 functioning to hold the inner and outer layers of the oocyst wall together
Bacchetti, R., Stevens, S., Lemgruber, L., Oliva, M. A. G., Sands, E. M., Alexandrou, K., Tinti, M., Robinson, L., Hanna, J. C., Seizova, S., Goddard, P., Vassalli, M. & Pawlowic, M. C. (Lead / Corresponding author), 20 Jul 2024, BioRxiv, 22 p.Research output: Working paper/Preprint › Preprint
File42 Downloads (Pure)