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Keyphrases
Skeletal muscle
100%
Impaired Insulin Secretion
50%
Nuclear factor-κB
42%
G Protein-coupled Receptor 55
42%
Dystrophy
42%
Mitochondrial Dysfunction
42%
Metabolic Tissues
42%
Adiposity
42%
Caveolin-3
42%
Integrated Stress Response
42%
CDK7
42%
Amino Acid Starvation
42%
Adaptation
42%
SLC38A2
42%
SNAT2
42%
Fold Increase
25%
Activating Transcription Factor 4 (ATF4)
25%
Adaptive Response
25%
Amino Acids
25%
Insulin Resistance
22%
Mitofusin 2 (Mfn2)
18%
Mitochondrial Respiratory Function
18%
Mitochondrial Morphology
18%
Skeletal muscle Cells
18%
Insulin Sensitivity
18%
Insulin Action
18%
Myotubes
16%
UCP3
16%
Glycogen Synthase kinase-3β (GSK-3β)
16%
General Control Nonderepressible 2 Kinase
16%
Insulin Signaling
13%
Obesity
13%
Peroxisome Proliferator-activated Receptor-γ coactivator-1α (PGC-1α)
12%
Mitochondrial Homeostasis
10%
Energy Metabolism
10%
Lipotoxicity
8%
Cellular ROS
8%
Interleukin-6
8%
Mitochondrial Fragmentation
8%
NF-κB Pathway
8%
Redox Status
8%
MRNA Expression
8%
Protein Abundance
8%
Mitophagy
8%
Palmitate
8%
Mitochondrial Dynamics
8%
Mitochondrial Bioenergetics
8%
Diabetes
8%
Critical Drivers
8%
Inflammation
8%
L6 Myotubes
8%
Nutrient Surplus
8%
Mitochondrial Function
8%
Metabolic Fuel
8%
Status Signaling
8%
Cyclin-dependent Kinase Inhibitor 2A (CDKN2A)
8%
Mitogen-activated Protein Kinase
8%
Off-target Effects
8%
Cellular Adaptation
8%
Regulatory System
8%
P38 MAP Kinase
8%
ERK MAP Kinase
8%
Cyclin-dependent Kinase
8%
Block System
8%
CDK7 Inhibitor
8%
Extracellular Amino Acid
8%
Doxycycline-inducible
8%
Amino Acid Transporter
8%
Pharmacological Inhibitors
8%
Repressor
8%
Multidrug-resistant
8%
Inhibitory Effect
8%
Protein Products
8%
MEK-ERK
8%
Protein Synthesis
8%
Mammalian Target of Rapamycin (mTOR)
8%
Flavopiridol
8%
Roscovitine
8%
L6 Myoblasts
6%
Myoblast
6%
Mitochondrial Respiration
6%
Reduced Physical Activity
5%
Phosphorylation
5%
Adipogenesis
5%
Enhanced Expression
5%
Liver Fat
5%
Endocannabinoid System
5%
Cannabinoid Ligands
5%
Tensin Homolog
5%
Positive Regulator
5%
Metabolic Dysfunction
5%
Non-classic
5%
Downstream Targets
5%
Null Mice
5%
Adipocyte
5%
Adipose Tissue
5%
3T3-L1 Adipocytes
5%
Protein Expression
5%
Antagonism
5%
Triglyceride Accumulation
5%
Insulin Receptor Substrate 1 (IRS1)
5%
Epididymal Fat
5%
Lysophosphatidylinositol
5%
Lipogenesis
5%
Expression Analysis
5%
Liver
5%
Phosphatase
5%
Endocrine Function
5%
Putative Drug Targets
5%
Receptor Antagonist
5%
Phospholipids
5%
Biochemistry, Genetics and Molecular Biology
Skeletal Muscle
94%
Deficiency
84%
Insulin Signaling
52%
Amino Acids
42%
G Protein Coupled Receptor
42%
Mitochondrial Disorder
42%
Caveolin 3
42%
Insulin
31%
Insulin Resistance
26%
MFN2
23%
Insulin Sensitivity
21%
SDHA
21%
UCP3
21%
Messenger RNA
21%
Kinase
16%
Activating Transcription Factor 4
16%
Cyclin-Dependent Kinase
16%
Phosphotransferase
16%
Homeostasis
12%
Lipotoxicity
10%
Energy Metabolism
10%
Adipocyte
10%
Respiratory Function
10%
Gene Repression
10%
Mitophagy
10%
Bioenergy
10%
Interleukin 6
10%
Phosphatase
10%
Palmitic Acid
10%
Glucose
10%
Upregulation
8%
Adaptive Response
8%
Mitogen-Activated Protein Kinase
8%
Transcription
8%
Amino Acid Transporter
8%
Protein Biosynthesis
8%
ATF4
8%
Repressor
8%
P38 Mitogen-Activated Protein Kinases
8%
Wild Type
7%
Protein Characterization
5%
Endocannabinoid System
5%
Physical Activity
5%
Lipogenesis
5%
Receptor Antagonist
5%
Tensin
5%
Endocrine Function
5%
Adipogenesis
5%
Triglyceride
5%
3T3-L1
5%
Knockout Mouse
5%
Insulin Receptor
5%
Expression Analysis
5%
Cannabinoid
5%
phosphorylation
5%
Protein Kinase B
5%
Lipid
5%