Research output per year
Research output per year
Search results
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2023
Improving the predictive power of xenograft and syngeneic anti-tumour studies using mice humanised for pathways of drug metabolism
Henderson, C. J., McLaren, A. W., Kapelyukh, Y. & Wolf, C. R. (Lead / Corresponding author), 27 Mar 2023, In: F1000 Research. 11, 15 p., 1081.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)69 Downloads (Pure) -
2022
Through a glass, darkly? HepaRG and HepG2 cells as models of human phase I drug metabolism
Stanley, L. A. (Lead / Corresponding author) & Wolf, C. R., 2022, In: Drug Metabolism Reviews. 54, 1, p. 46-62 17 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile17 Citations (Scopus)128 Downloads (Pure) -
2021
Quantifying ERK activity in response to inhibition of the BRAFV600E-MEK-ERK cascade using mathematical modelling
Hamis, S. J. (Lead / Corresponding author), Kapelyukh, Y., McLaren, A., Henderson, C. J., Wolf, C. R. & Chaplain, M. A. J., 23 Nov 2021, In: British Journal of Cancer. 125, p. 1552-1560 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)101 Downloads (Pure) -
2019
An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials
Henderson, C. J., Kapelyukh, Y., Scheer, N., Rode, A., McLaren, A., MacLeod, K., Lin, D., Wright, J., Stanley, L. A. & Wolf, C. R. (Lead / Corresponding author), Jun 2019, In: Drug Metabolism and Disposition. 47, 6, p. 601-615 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)256 Downloads (Pure) -
Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
Kapelyukh, Y., Henderson, C. J., Scheer, N., Rode, A. & Wolf, R. (Lead / Corresponding author), 1 Aug 2019, In: Drug Metabolism and Disposition. 47, 8, p. 907-918 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)188 Downloads (Pure)