DIRECT: Diabetes Research on Patient Stratification (joint with 25 other partners)

Project Details

StatusActive
Effective start/end date1/02/12 → 28/02/27

Funding

  • (115317): £463,529.00
  • COMMISSION OF THE EUROPEAN COMMUNITIES (115317-DIRECT): £5,923,228.00

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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  • The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study

    Eriksen, R., White, M. C., Dawed, A. Y., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, E. L., Koivula, R. W., Bizzotto, R., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F. D., Tsirigos, K. D., Brunak, S., Viñuela, A. & Mahajan, A. & 26 others, McDonald, T. J., Kokkola, T., Rutters, F., Beulens, J., Muilwijk, M., Blom, M., Elders, P., Hansen, T. H., Fernandez-Tajes, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, O., Ruetten, H., Forgie, I., Holst, J. J., Thomsen, H. S., Ridderstråle, M., Bell, J. D., Adamski, J., Franks, P. W., Hansen, T., Holmes, E., Frost, G. (Lead / Corresponding author) & Pearson, E. R. (Lead / Corresponding author), 1 Sept 2024, In: Journal of Clinical Endocrinology & Metabolism. 109, 9, p. e1697-e1707 11 p., dgae119.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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    58 Downloads (Pure)

  • Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models

    IMI DIRECT Consortium, Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Rodríguez, C. L., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A. & Koivula, R. & 34 others, Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Hong, M.-G., Musholt, P. B., De Masi, F., Vogt, J., Pedersen, H. K., Gudmundsdottir, V., Jones, A., Kennedy, G., Bell, J., Thomas, E. L., Frost, G., Thomsen, H., Hansen, E., Hansen, T. H., Vestergaard, H., Muilwijk, M., Blom, M. T., 't Hart, L. M., Pattou, F., Raverdy, V., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Mourby, M., Forgie, I., Pearson, E., Rasmussen, S. (Lead / Corresponding author) & Brunak, S. (Lead / Corresponding author), Mar 2023, In: Nature Biotechnology. 41, p. 399-408 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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    56 Citations (Scopus)
    97 Downloads (Pure)

  • Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

    Brown, A. A., Fernandez-Tajes, J. J., Hong, M.-G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T.-D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T. & Hansen, T. H. & 39 others, Hattersley, A. T., Heggie, A. J., Howald, C., Jones, A. G., Kokkola, T., Laakso, M., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Mourby, M., Musholt, P. B., Nilsson, B., Pattou, F., Penet, D., Raverdy, V., Ridderstråle, M., Romano, L., Rutters, F., Sharma, S., Teare, H., Hart, L., Tsirigos, K. D., Vangipurapu, J., Vestergaard, H., Brunak, S., Franks, P. W., Frost, G., Grallert, H., Jablonka, B., McCarthy, M., Pavo, I., Pedersen, O., Ruetten, H., Walker, M., The DIRECT consortium, Pearson, E. R., Dermitzakis, E. T. (Lead / Corresponding author) & Viñuela, A. (Lead / Corresponding author), 21 Aug 2023, In: Nature Communications. 14, 17 p., 5062.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    11 Citations (Scopus)
    107 Downloads (Pure)
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