DIRECT: Diabetes Research on Patient Stratification (joint with 25 other partners)

Project Details

StatusActive
Effective start/end date1/02/1228/02/27

Funding

  • (115317): £463,529.00
  • COMMISSION OF THE EUROPEAN COMMUNITIES (115317-DIRECT): £5,923,228.00

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
  • Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models

    IMI DIRECT Consortium, Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Rodríguez, C. L., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., & 34 othersMahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Hong, M-G., Musholt, P. B., De Masi, F., Vogt, J., Pedersen, H. K., Gudmundsdottir, V., Jones, A., Kennedy, G., Bell, J., Thomas, E. L., Frost, G., Thomsen, H., Hansen, E., Hansen, T. H., Vestergaard, H., Muilwijk, M., Blom, M. T., 't Hart, L. M., Pattou, F., Raverdy, V., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Mourby, M., Forgie, I., Pearson, E., Rasmussen, S. & Brunak, S., Mar 2023, In: Nature Biotechnology. 41, p. 399-408 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    22 Citations (Scopus)
    30 Downloads (Pure)
  • Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

    Brown, A. A., Fernandez-Tajes, J. J., Hong, M-G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T-D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T., Hansen, T. H., & 39 othersHattersley, A. T., Heggie, A. J., Howald, C., Jones, A. G., Kokkola, T., Laakso, M., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Mourby, M., Musholt, P. B., Nilsson, B., Pattou, F., Penet, D., Raverdy, V., Ridderstråle, M., Romano, L., Rutters, F., Sharma, S., Teare, H., Hart, L., Tsirigos, K. D., Vangipurapu, J., Vestergaard, H., Brunak, S., Franks, P. W., Frost, G., Grallert, H., Jablonka, B., McCarthy, M., Pavo, I., Pedersen, O., Ruetten, H., Walker, M., The DIRECT consortium, Pearson, E. R., Dermitzakis, E. T. & Viñuela, A., 21 Aug 2023, In: Nature Communications. 14, 17 p., 5062.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    2 Citations (Scopus)
    29 Downloads (Pure)
  • Pharmacogenomics of GLP-1 Receptor Agonists: a genome-wide analysis of observational data and large randomised controlled trials

    Dawed, A. Y., Mari, A., Brown, A., McDonald, T. J., Li, L., Wang, S., Hong, M-G., Sharma, S., Robertson, N. R., Mahajan, A., Wang, X., Walker, M., Gough, S., 't Hart, L. M., Zhou, K., Forgie, I., Ruetten, H., Pavo, I., Bhatnagar, P., Jones, A. G., & 1 othersPearson, E. R., 1 Jan 2023, In: The Lancet Diabetes and Endocrinology. 11, 1, p. 33-41 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    22 Citations (Scopus)
    158 Downloads (Pure)