DIRECT: Diabetes Research on Patient Stratification (joint with 25 other partners)

Project Details

StatusFinished
Effective start/end date1/02/171/02/19

Funding

  • (115317): £463,529.00

Research Output

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

Grubb, A. L., McDonald, T. J., Rutters, F., Donnelly, L., Hattersley, A. T., Oram, R. A., Palmer, C., van der Heijden, A. A., Carr, F., Elders, P. J. M., Weedon, M., Slieker, R. C., 't Hart, L. M., Pearson, E., Shields, B. M. & Jones, A. G., 1 Feb 2019, In : Diabetes Care. 42, 2, p. 208-214 7 p.

Research output: Contribution to journalArticle

Open Access
File
  • 9 Citations (Scopus)
    357 Downloads (Pure)

    Genome-Wide and Abdominal MRI-Imaging Data Provides Evidence that a Genetically Determined Favourable Adiposity Phenotype is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease and Hypertension

    Ji, Y., Yiorkas, A. M., Frau, F., Mook-Kanamori, D., Staiger, H., Thomas, E. L., Atabaki-Pasdar, N., Campbell, A., Tyrrell, J., Jones, S. E., Beaumont, R. N., Wood, A. R., Tuke, M. A., Ruth, K. S., Mahajan, A., Murray, A., Freathy, R. M., Weedon, M. N., Hattersley, A. T., Hayward, C. & 11 others, Machann, J., Häring, H-U., Franks, P., de Mutsert, R., Pearson, E., Stefan, N., Frayling, T. M., Allebrandt, K. V., Bell, J. D., Blakemore, A. I. & Yaghootkar, H., 1 Jan 2019, In : Diabetes. 68, 1, p. 207-219 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 20 Citations (Scopus)
    280 Downloads (Pure)

    Motivations for data sharing-views of research participants from four European countries: A DIRECT study

    Shah, N., Coathup, V., Teare, H., Forgie, I., Giordano, G. N., Hansen, T. H., Groeneveld, L., Hudson, M., Pearson, E., Ruetten, H. & Kaye, J., 30 Jan 2019, In : European Journal of Human Genetics. 27, 5, p. 721-729 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 5 Citations (Scopus)
    98 Downloads (Pure)