Skip to main navigation Skip to search Skip to main content

DIRECT: Diabetes Research on Patient Stratification (joint with 25 other partners)

Project Details

StatusActive
Effective start/end date1/02/12 → 28/02/27

Funding

  • COMMISSION OF THE EUROPEAN COMMUNITIES (115317-DIRECT): £5,923,228.00

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
View full fingerprint

  • A biological-systems-based analysis using proteomic and metabolic network inference reveals mechanistic insights into hepatic steatosis

    Atabaki, N. N. (Lead / Corresponding author), Coral, D. E., Pomares-Millan, H., Smith, K., Behjat, H. H., Koivula, R. W., Tura, A., Miller, H., Pinnick, K., Agudelo, L., Allin, K. H., Brown, A. A., Chabanova, E., Chmura, P. J., Jacobsen, U. P., Dawed, A. Y., Elders, P. J. M., Fernandez-Tajes, J. J., Forgie, I. M. & Haid, M. & 43 others, Hansen, T. H., Jones, A. G., Kokkola, T., Kalamajski, S., Mahajan, A., McDonald, T. J., McEvoy, D., Muilwijk, M., Tsirigos, K. D., Vangipurapu, J., van Oort, S., Vestergaard, H., Adamski, J., Beulens, J. W., Brunak, S., Dermitzakis, E. T., Giordano, G. N., Gupta, R., Hansen, T., t'Hart, L. M., Hattersley, A. T., Hodson, L., Laakso, M., Loos, R. J. F., Merino, J., Ohlsson, M., Pedersen, O., Ridderstråle, M., Ruetten, H., Rutters, F., Schwenk, J. M., Tomlinson, J., Walker, M., Yaghootkar, H., Karpe, F., McCarthy, M. I., Thomas, E. L., Bell, J. D., Mari, A., Pavo, I., Pearson, E. R., Viñuela, A. & Franks, P. W. (Lead / Corresponding author), May 2026, In: Metabolism: Clinical and Experimental. 178, 15 p., 156552.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    4 Downloads (Pure)

  • Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists

    Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Mayrhofer, J. E., Lindquist, P., Silva, P. N., Goga, A., Trüllinger, G. O., Godbersen, S., Sengupta, S., Kaufmann, A., Thomsen, S. K., Hartmann, B., Chen, Y. C., Jonsson, A. E., Kabakci, H., Thaman, S. & Grarup, N. & 25 others, Have, C. T., Pallo, L. P., Faerch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O., Walker, M., Sun, H., Jennison, C., Hattersley, A. T., Rehfeld, J. F., Holman, R. R., Verchere, B. C., Hansen, T., Karpe, F., Holst, J. J., Rosenkilde, M. M., Jones, A. G., Ristow, M., McCarthy, M. I., Pearson, E. R., Stoffel, M. & Gloyn, A. L. (Lead / Corresponding author), 13 Apr 2026, In: Genome Medicine. 18, 1, 40.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    1   Link opens in a new tab Citation (Scopus)
    4 Downloads (Pure)

  • Bayesian network imputation methods applied to multi-omics data identify putative causal relationships in a type 2 diabetes dataset containing incomplete data: An IMI DIRECT Study

    Howey, R., Adam, J., Adamski, J., Atabaki, N. N., Brunak, S., Chmura, P. J., De Masi, F., Dermitzakis, E. T., Fernandez-Tajes, J. J., Forgie, I. M., Franks, P. W., Giordano, G. N., Haid, M., Hansen, T., Hansen, T. H., Harms, P. P., Hattersley, A. T., Hong, M. G., Jacobsen, U. P. & Jones, A. G. & 20 others, Koivula, R. W., Kokkola, T., Mahajan, A., Mari, A., McCarthy, M. I., McDonald, T. J., Musholt, P. B., Pavo, I., Pearson, E. R., Pedersen, O., Ruetten, H., Rutters, F., Schwenk, J. M., Sharma, S., T Hart, L. M., Vestergaard, H., Walker, M., The IMI DIRECT consortium, Viñuela, A. & Cordell, H. J. (Lead / Corresponding author), 15 Jul 2025, In: PLoS Genetics. 21, 7, 20 p., e1011776.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    12 Downloads (Pure)
View all 25 research outputs