Research output per year
Research output per year
Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 1/02/11 → 1/07/17 |
Funding
- Wellcome Trust (Diana Tay): £336,000.00
- Wellcome Trust (092340 via milestone): £6,535,971.00
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis
Thomas, M., Brand, S., De Rycker, M., Zuccotto, F., Lukac, I., Dodd, P., Ko, E-J., Manthri, S., McGonagle, K., Osuna-Cabello, M., Riley, J., Pont, C., Simeons, F., Stojanovski, L., Thomas, J., Thompson, S., Viayna, E., Fiandor, J. M., Martín, J., Wyatt, P. G. & 4 others, , 13 May 2021, In: Journal of Medicinal Chemistry. 64, 9, p. 5905-5930 26 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)86 Downloads (Pure) -
Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase
Torrie, L. S., Robinson, D. A., Thomas, M. G., Hobrath, J. V., Shepherd, S. M., Post, J. M., Ko, E. J., Ferreira, R. A., Mackenzie, C. J., Wrobel, K., Edwards, D. P., Gilbert, I. H., Gray, D. W., Fairlamb, A. H. & De Rycker, M., 8 May 2020, In: ACS Infectious Diseases. 6, 5, p. 1044-1057 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)67 Downloads (Pure) -
Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity
Thomas, M., De Rycker, M., Wall, R. J., Spinks, D., Epemolu, O., Manthri, S., Norval, S., Osuna-Cabello, M., Patterson, S., Riley, J., Simeons, F. R. C., Stojanovski, L., Thomas, J., Thompson, S., Naylor, C., Fiandor, J. M., Wyatt, P. G., Marco, M., Wyllie, S., Read, K. D. & 2 others, , 10 Sep 2020, In: Journal of Medicinal Chemistry. 63, 17, p. 9523-9539 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)136 Downloads (Pure)