Research output per year
Research output per year
- 48 results
Search results
-
2023
An allele-selective inter-chromosomal protein bridge supports monogenic antigen expression in the African trypanosome
Correia Faria, J. R. (Lead / Corresponding author), Tinti, M., Marques, C. A., Zoltner, M., Yoshikawa, H., Field, M. C. & Horn, D. (Lead / Corresponding author), 11 Dec 2023, In: Nature Communications. 14, 1, 18 p., 8200.Research output: Contribution to journal › Article › peer-review
Open AccessFile54 Downloads (Pure) -
2021
Aurora B switches relative strength of kinetochore–microtubule attachment modes for error correction
Doodhi, H. (Lead / Corresponding author), Kasciukovic, T., Clayton, L. & Tanaka, T. U. (Lead / Corresponding author), 7 Jun 2021, In: Journal of Cell Biology. 220, 6, 14 p., e202011117.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)232 Downloads (Pure) -
Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes
Faria, J., Luzak, V., Müller, L. S. M., Brink, B. G., Hutchinson, S., Glover, L., Horn, D. (Lead / Corresponding author) & Siegel, T. N. (Lead / Corresponding author), Mar 2021, In: Nature Microbiology. 6, p. 289-300 12 p.Research output: Contribution to journal › Article › peer-review
39 Citations (Scopus) -
2020
Characterisation of the biochemical and cellular roles of native and pathogenic amelogenesis imperfecta mutants of FAM83H
Tachie-Menson, T., Gázquez-Gutiérrez, A., Fulcher, L., Macartney, T., Wood, N., Varghese, J., Gourlay, R., Filipe Soares, R. & Sapkota, G. (Lead / Corresponding author), Aug 2020, In: Cellular Signalling. 72, 17 p., 109632.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)238 Downloads (Pure) -
Comment on “Rivalry in Bacillus subtilis colonies: enemy or family?”
Matoz-Fernandez, D., Arnaouteli, S., Porter, M., MacPhee, C. E., Stanley-Wall, N. R. (Lead / Corresponding author) & Davidson, F. A. (Lead / Corresponding author), 7 Apr 2020, In: Soft Matter. 16, 13, p. 3344-3346 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)91 Downloads (Pure) -
Genomic Differences between Listeria monocytogenes EGDe Isolates Reveal Crucial Roles for SigB and Wall Rhamnosylation in Biofilm Formation
Hsu, C.-Y., Cairns, L., Hobley, L., Abbott, J., O'Byrne, C. & Stanley-Wall, N. R. (Lead / Corresponding author), 11 Mar 2020, In: Journal of Bacteriology. 202, 7, 13 p., e00692-19.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)83 Downloads (Pure) -
2019
A family of Type VI secretion system effector proteins that form ion-selective pores
Mariano, G., Trunk, K., Williams, D. J., Monlezun, L., Strahl, H., Pitt, S. J. & Coulthurst, S. (Lead / Corresponding author), 2 Dec 2019, In: Nature Communications. 10, 1, p. 1-15 15 p., 5484.Research output: Contribution to journal › Article › peer-review
Open AccessFile46 Citations (Scopus)171 Downloads (Pure) -
A post-transcriptional respiratome regulon in trypanosomes
Trenaman, A., Glover, L., Hutchinson, S. & Horn, D. (Lead / Corresponding author), 26 Jul 2019, In: Nucleic Acids Research. 47, 13, p. 7063-7077 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)105 Downloads (Pure) -
Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis
Booth, A. J. R., Yue, Z., Eykelenboom, J. K., Stiff, T., Luxton, G. W. G., Hochegger, H. & Tanaka, T. U. (Lead / Corresponding author), 16 Jul 2019, In: eLife. 8, p. 1-21 21 p., e46902.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Citations (Scopus)300 Downloads (Pure) -
desynaptic5 carries a spontaneous semi-dominant mutation affecting Disrupted Meiotic cDNA 1 in barley
Colas, I., Barakate, A. (Lead / Corresponding author), Macaulay, M., Schreiber, M., Stephens, J., Vivera, S., Halpin, C., Waugh, R. (Lead / Corresponding author) & Ramsay, L. (Lead / Corresponding author), 1 May 2019, In: Journal of Experimental Botany. 70, 10, p. 2683-2698 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)170 Downloads (Pure) -
FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning
Fulcher, L. J., He, Z., Mei, L., Macartney, T. J., Wood, N. T., Prescott, A. R., Whigham, A., Varghese, J., Gourlay, R., Ball, G., Clarke, R., Campbell, D., Maxwell, C. A. & Sapkota, G. P. (Lead / Corresponding author), 1 Sept 2019, In: EMBO Reports. 20, 9, p. 1-19 19 p., e47495.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)222 Downloads (Pure) -
Live imaging of marked chromosome regions reveals their dynamic resolution and compaction in mitosis
Eykelenboom, J., Gierlinski, M., Yue, Z., Hegarat, N., Pollard, H., Fukagawa, T., Hochegger, H. & Tanaka, T. U. (Lead / Corresponding author), 6 May 2019, In: Journal of Cell Biology. 218, 5, p. 1531-1552 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)382 Downloads (Pure) -
Pulcherrimin formation controls growth arrest of the Bacillus subtilis biofilm
Arnaouteli, S., Matoz Fernandez, D., Porter, M., Kalamara, M., Abbott, J., MacPhee, C. E., Davidson, F. & Stanley-Wall, N. (Lead / Corresponding author), 2 Jul 2019, In: Proceedings of the National Academy of Sciences. 116, 27, p. 13553-13562 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Citations (Scopus)195 Downloads (Pure) -
Triggering MSR1 promotes JNK-mediated inflammation in IL-4 activated macrophages
Guo, M., Härtlova, A. (Lead / Corresponding author), Gierlinski, M., Prescott, A., Castellvi, J., Hernandez Losa, J., Petersen, S. K., Wenzel, U. A., Dill, B. D., Emmerich, C. H., Ramon Y Cajal, S., Russell, D. G. & Trost, M. (Lead / Corresponding author), 3 Jun 2019, In: EMBO Journal. 38, 11, p. 1-15 15 p., e100299.Research output: Contribution to journal › Article › peer-review
Open AccessFile66 Citations (Scopus)302 Downloads (Pure) -
2018
6-hydroxydopamine (6-OHDA) Oxidative Stress Assay for Observing Dopaminergic Neuron Loss in Caenorhabditis elegans
Offenburger, S.-L. (Lead / Corresponding author) & Gartner, A., 20 Sept 2018, In: Bio-Protocol. 8, 18, 12 p., e3025.Research output: Contribution to journal › Article › peer-review
Open AccessFile247 Downloads (Pure) -
6-OHDA-induced dopaminergic neurodegeneration in Caenorhabditis elegans is promoted by the engulfment pathway and inhibited by the transthyretin-related protein TTR-33
Offenburger, S.-L., Ho, X. Y., Tachie-Menson, T., Coakley, S., Hilliard, M. A. & Gartner, A. (Lead / Corresponding author), 18 Jan 2018, In: PLoS Genetics. 14, 1, p. 1-27 27 p., e1007125.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)283 Downloads (Pure) -
Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
McWilliams, T. G. (Lead / Corresponding author), Prescott, A. R., Montava-Garriga, L., Ball, G., Singh, F., Barini, E., Muqit, M. M. K., Brooks, S. P. & Ganley, I. G. (Lead / Corresponding author), 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 439-449.e5 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile405 Citations (Scopus)311 Downloads (Pure) -
DHX15 regulates CMTR1-dependent gene expression and cell proliferation
Inesta-Vaquera, F., Chaugule, V. K., Galloway, A., Chandler, L., Rojas-Fernandez, A., Weidlich, S., Peggie, M. & Cowling, V. (Lead / Corresponding author), 18 Jun 2018, In: Life Science Alliance. 1, 3, 18 p., e201800092.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)226 Downloads (Pure) -
Effects of hypo O-GlcNAcylation on Drosophila development
Mariappa, D. N., Ferenbach, A. & van Aalten, D. M. F. (Lead / Corresponding author), 11 May 2018, In: Journal of Biological Chemistry. 293, 19, p. 7209-7221 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)184 Downloads (Pure) -
LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis
Hong, Y., Sonneville, R., Wang, B., Scheidt, V., Meier, B., Woglar, A., Demetriou, S., Labib, K., Jantsch, V. & Gartner, A. (Lead / Corresponding author), 20 Feb 2018, In: Nature Communications. 9, p. 1-11 11 p., 728.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)271 Downloads (Pure) -
Mutations in Caenorhabditis elegans neuroligin-like glit-1, the apoptosis pathway and the calcium chaperone crt-1 increase dopaminergic neurodegeneration after 6-OHDA treatment
Offenburger, S.-L., Jongsma, E. & Gartner, A. (Lead / Corresponding author), 18 Jan 2018, In: PLoS Genetics. 14, 1, p. 1-34 34 p., e1007106.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)283 Downloads (Pure) -
Optimization of a “Bump-and-Hole” Approach to Allele-Selective BET Bromodomain Inhibition
Runcie, A., Zengerle, M., Chan, K. H., Testa, A., Van Beurden, L., Baud, M., Epemolu, R., Ellis, L., Read, K., Coulthard, V., Brien, A. & Ciulli, A. (Lead / Corresponding author), 7 Mar 2018, In: Chemical Science. 9, 9, p. 2452-2468 17 p., 2452.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)253 Downloads (Pure) -
Phosphorylation of Parkin at Serine65 is essential for its activation in vivo
McWilliams, T. G. (Lead / Corresponding author), Barini, E., Pohjolan-Pirhonen, R., Brooks, S. P., Singh, F., Burel, S., Balk, K., Kumar, A., Montava Garriga, L., Prescott, A., Hassoun, S. M., Mouton-Liger, F., Ball, G., Hills, R., Knebel, A., Ulusoy, A., Di Monte, D. A., Tamjar, J., Antico, O. & Fears, K. & 11 others, , Nov 2018, In: Open Biology. 8, 11, 18 p., 181108.Research output: Contribution to journal › Article › peer-review
Open AccessFile78 Citations (Scopus)297 Downloads (Pure) -
The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans
Hong, Y., Velkova, M., Silva, N., Jagut, M., Scheidt, V., Labib, K., Jantsch, V. & Gartner, A. (Lead / Corresponding author), 7 Jun 2018, In: PLoS Genetics. 14, 6, p. 1-22 22 p., e1007453.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus)233 Downloads (Pure) -
The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms
Fulcher, L., Bozatzi, P., Tachie-Menson, T., Wu, K., Cummins, T. D., Bufton, J. C., Pinkas, D. M., Dunbar, K., Shrestha, S., Wood, N., Weidlich, S., Macartney, T., Varghese, J., Gourlay, R., Campbell, D., Dingwell, K. S., Smith, J. C., Bullock, A. N. & Sapkota, G. (Lead / Corresponding author), 22 May 2018, In: Science Signaling. 11, 531, p. 1-16 16 p., eaao2341.Research output: Contribution to journal › Article › peer-review
Open AccessFile72 Citations (Scopus)328 Downloads (Pure) -
2017
A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans
González-Huici, V., Wang, B. & Gartner, A. (Lead / Corresponding author), 1 Aug 2017, In: Genetics. 206, 4, p. 1853-1864 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)254 Downloads (Pure) -
Autophagosomes cooperate in the degradation of intracellular C-terminal fragments of the amyloid precursor protein via the MVB/lysosomal pathway
González, A. E., Muñoz, V. C., Cavieres, V. A., Bustamante, H. A., Cornejo, V.-H., Januário, Y. C., González, I., Hetz, C., daSilva, L. L., Rojas-Fernández, A., Hay, R. T., Mardones, G. A. & Burgos, P. V. (Lead / Corresponding author), Jun 2017, In: FASEB Journal. 31, 6, p. 2446-2459 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Citations (Scopus)308 Downloads (Pure) -
Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation
Bertolini, S., Wang, B., Meier, B., Hong, Y. & Gartner, A. (Lead / Corresponding author), 1 Dec 2017, In: G3: Genes | Genomes | Genetics. 7, 12, p. 3875-3885 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)297 Downloads (Pure) -
Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination
Kasioulis, I., Das, R. M. & Storey, K. G. (Lead / Corresponding author), 23 Oct 2017, In: eLife. 6, p. 1-31 31 p., e26215.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Citations (Scopus)274 Downloads (Pure) -
The Ndc80 complex targets Bod1 to human mitotic kinetochores
Schleicher, K., Porter, M., ten Have, S., Sundaramoorthy, R., Porter, I. M. & Swedlow, J. R. (Lead / Corresponding author), 15 Nov 2017, In: Open Biology. 7, p. 1-14 14 p., 170099.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)211 Downloads (Pure) -
Transcription factors NRF2 and HSF1 have opposing functions in autophagy
Dayalan Naidu, S., Dikovskaya, D., Gaurilcikaite, E., Knatko, E., Healy, Z. R., Mohan, H., Koh, G., Laurell, A., Ball, G., Olagnier, D., de la Vega, L., Ganley, I., Talalay, P. & Dinkova-Kostova, A. (Lead / Corresponding author), 8 Sept 2017, In: Scientific Reports. 7, p. 1-12 12 p., 11023.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)288 Downloads (Pure) -
2016
CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription
Aregger, M., Kaskar, A., Varshney, D., Fernandez-Sanchez, M. E., Inesta-Vaquera, F. A., Weidlich, S. & Cowling, V. H. (Lead / Corresponding author), 3 Mar 2016, In: Molecular Cell. 61, 5, p. 734-746 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Citations (Scopus)202 Downloads (Pure) -
High resolution imaging reveals heterogeneity in chromatin states between cells that is not inherited through cell division
Dickerson, D., Gierlinski, M., Singh, V., Kitamura, E., Ball, G., Tanaka, T. U. & Owen-Hughes, T. (Lead / Corresponding author), 8 Sept 2016, In: BMC Cell Biology. 17, 16 p., 33.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)253 Downloads (Pure) -
Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells
Moreno, A., Carrington, J. T., Albergante, L., Al Mamun, M., Haagensen, E. J., Komseli, E.-S., Gorgoulis, V. G., Newman, T. J. & Blow, J. (Lead / Corresponding author), 27 Sept 2016, In: Proceedings of the National Academy of Sciences. 113, 39, p. E5757-E5764 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile86 Citations (Scopus)558 Downloads (Pure) -
VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes
Glover, L., Hutchinson, S., Alsford, S. & Horn, D. (Lead / Corresponding author), 28 Jun 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. 7225-7230 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile73 Citations (Scopus)415 Downloads (Pure) -
2015
Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos
Sonneville, R., Craig, G., Labib, K., Gartner, A. (Lead / Corresponding author) & Blow, J. J. (Lead / Corresponding author), 21 Jul 2015, In: Cell Reports. 12, 3, p. 405-417 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)283 Downloads (Pure) -
Dual functionality of O-GlcNAc transferase is required for Drosophila development
Mariappa, D., Zheng, X., Schimpl, M., Raimi, O., Ferenbach, A. T., Müller, H.-A. J. & van Aalten, D. M. F. (Lead / Corresponding author), 16 Dec 2015, In: Open Biology. 5, 12, 10 p., 150234.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)170 Downloads (Pure) -
mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival
Munson, M. J., Allen, G. F. G., Toth, R., Campbell, D. G., Lucocq, J. M. & Ganley, I. G. (Lead / Corresponding author), 2 Sept 2015, In: EMBO Journal. 34, 17, p. 2272-2290 19 p.Research output: Contribution to journal › Article › peer-review
Open Access131 Citations (Scopus) -
SIMcheck: A toolbox for successful super-resolution structured illumination microscopy
Ball, G., Demmerle, J., Kaufmann, R., Davis, I., Dobbie, I. M. & Schermelleh, L., 3 Nov 2015, In: Scientific Reports. 5, p. 1-12 12 p., 15915.Research output: Contribution to journal › Article › peer-review
Open AccessFile215 Citations (Scopus)226 Downloads (Pure) -
The evolution of structured illumination microscopy in studies of HIV
Marno, K., Al'Zoubi, L., Pearson, M., Posch, M., McKnight, Á. & Wheeler, A. P., 2015, In: Methods. 88, p. 20-27 8 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
2014
A holin and an endopeptidase are essential for chitinolytic protein secretion in Serratia marcescens
Hamilton, J. J., Marlow, V. L., Owen, R. A., Costa, M. D. A. A., Guo, M., Buchanan, G., Chandra, G., Trost, M., Coulthurst, S. J., Palmer, T., Stanley-Wall, N. R. & Sargent, F. (Lead / Corresponding author), 8 Dec 2014, In: Journal of Cell Biology. 207, 5, p. 615-626 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)233 Downloads (Pure) -
Apical Abscission Alters Cell Polarity and Dismantles the Primary Cilium During Neurogenesis
Das, R. M. & Storey, K. G. (Lead / Corresponding author), 10 Jan 2014, In: Science. 343, 6167, p. 200-204 5 p.Research output: Contribution to journal › Article › peer-review
131 Citations (Scopus) -
PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation
Hands, K. J., Cuchet-Lourenco, D., Everett, R. D. & Hay, R. T. (Lead / Corresponding author), 15 Jan 2014, In: Journal of Cell Science. 127, 2, p. 365-375 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)306 Downloads (Pure) -
SUMO chain-induced dimerization activates RNF4
Rojas-Fernandez, A., Plechanovová, A., Hattersley, N., Jaffray, E., Tatham, M. H. & Hay, R. T. (Lead / Corresponding author), 20 Mar 2014, In: Molecular Cell. 53, 6, p. 880-92 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Citations (Scopus)239 Downloads (Pure) -
Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans
Masoudi, N., Ibanez-Cruceyra, P., Offenburger, S.-L., Holmes, A. & Gartner, A. (Lead / Corresponding author), 4 Dec 2014, In: PLoS Genetics. 10, 12, 15 p., e1004767.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)202 Downloads (Pure) -
The Synaptonemal Complex Protein ZYP1 Is Required for Imposition of Meiotic Crossovers in Barley
Barakate, A., Higgins, J. D., Vivera, S., Stephens, J., Perry, R. M., Ramsay, L., Colas, I., Oakey, H., Waugh, R., Franklin, F. C. H., Armstrong, S. J. & Halpin, C. (Lead / Corresponding author), Feb 2014, In: The Plant Cell. 26, 2, p. 729-740 12 p.Research output: Contribution to journal › Article › peer-review
63 Citations (Scopus) -
2013
Characterization of cell death inducing Phytophthora capsici CRN effectors suggests diverse activities in the host nucleus
Stam, R., Howden, A. J. M., Delgado Cerezo, M., Amaro, T. M. M. M., Motion, G. B., Pham, J. & Huitema, E. (Lead / Corresponding author), 21 Oct 2013, In: Frontiers in Plant Science. 4, 11 p., 387.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases
Agostinho, A., Meier, B., Sonneville, R., Jagut, M., Woglar, A., Blow, J., Jantsch, V. & Gartner, A. (Lead / Corresponding author), 18 Jul 2013, In: PLoS Genetics. 9, 7, e1003591.Research output: Contribution to journal › Article › peer-review
76 Citations (Scopus)