Elucidating the Molecular Mechanism of Intracellular DNA Recognition by the Innate Immune Sensor IFI16 (Career Development Fellowship)

  • Unterholzner, Leonie (Investigator)
  • Watts, Colin (Investigator)

Project Details

StatusFinished
Effective start/end date1/02/1331/01/18

Funding

  • Medical Research Council (MR/K00655X/1): £609,624.10

Research Output

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

Almine, J. F., O'Hare, C. A. J., Dunphy, G., Haga, I. R., Naik, R. J., Atrih, A., Connolly, D. J., Taylor, J., Kelsall, I. R., Bowie, A. G., Beard, P. M. & Unterholzner, L., 13 Feb 2017, In : Nature Communications. 8, p. 1-15 15 p., 14392.

Research output: Contribution to journalArticle

Open Access
File
  • 98 Citations (Scopus)
    252 Downloads (Pure)

    The interferon response to intracellular DNA: Why so many receptors?

    Unterholzner, L., Nov 2013, In : Immunobiology. 218, 11, p. 1312-1321 10 p.

    Research output: Contribution to journalArticle

  • 142 Citations (Scopus)