Elucidating the Molecular Mechanism of Intracellular DNA Recognition by the Innate Immune Sensor IFI16 (Career Development Fellowship)

Research output

Research output per year 2013 2017

• 2 Article

Research output per year

Research output per year

Search results

• 2017

  IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

  Almine, J. F., O'Hare, C. A. J., Dunphy, G., Haga, I. R., Naik, R. J., Atrih, A., Connolly, D. J., Taylor, J., Kelsall, I. R., Bowie, A. G., Beard, P. M. & Unterholzner, L., 13 Feb 2017, In: Nature Communications. 8, p. 1-15 15 p., 14392.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Keratinocytes
  • interferon
  • cyclic AMP
  • GMP synthase (glutamine-hydrolyzing)
  • cyclic guanosine monophosphate-adenosine monophosphate
  123 Citations (Scopus)

  290 Downloads (Pure)
• 2013

  The interferon response to intracellular DNA: Why so many receptors?

  Unterholzner, L., Nov 2013, In: Immunobiology. 218, 11, p. 1312-1321 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Interferons
  • DNA
  • DNA receptor
  • Interferon Type I
  • Autoimmunity
  149 Citations (Scopus)