Research output per year
Research output per year
- 16 results
Search results
-
2015
An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice
Akbar, N., Nanda, S., Belch, J., Cohen, P. & Khan, F. (Lead / Corresponding author), 4 Feb 2015, In: Arthritis Research & Therapy. 17, 10 p., 22.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)426 Downloads (Pure) -
Discovery of type II inhibitors of tgfβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2)
Tan, L., Nomanbhoy, T., Gurbani, D., Patricelli, M., Hunter, J., Geng, J., Herhaus, L., Zhang, J., Pauls, E., Ham, Y., Choi, H. G., Xie, T., Deng, X., Buhrlage, S. J., Sim, T., Cohen, P., Sapkota, G., Westover, K. D. & Gray, N. S., 8 Jan 2015, In: Journal of Medicinal Chemistry. 58, 1, p. 183-196 14 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Citations (Scopus) -
Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting
Emmerich, C. H. (Lead / Corresponding author) & Cohen, P., 9 Oct 2015, In: Biochemical and Biophysical Research Communications. 466, 1, p. 1-14 14 p.Research output: Contribution to journal › Article › peer-review
Open Access93 Citations (Scopus) -
Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members
Malik, N., Vollmer, S., Nanda, S. K., Lopez-Pelaez, M., Prescott, A., Gray, N. & Cohen, P. (Lead / Corresponding author), 15 Jun 2015, In: Biochemical Journal. 468, 3, p. 363-372 10 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
2014
An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation
Zhang, J., Clark, K., Lawrence, T., Peggie, M. W. & Cohen, P. (Lead / Corresponding author), 1 Aug 2014, In: Biochemical Journal. 461, 3, p. 531-537 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile85 Citations (Scopus)276 Downloads (Pure) -
IRAK-1 bypasses priming and directly links TLRs torapid NLRP3 inflammasome activation
Lin, K. M., Hu, W., Troutman, T. D., Jennings, M., Brewer, T., Li, X., Nanda, S., Cohen, P., Thomas, J. A. & Pasare, C., 14 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 2, p. 775-780 6 p.Research output: Contribution to journal › Article › peer-review
Open Access229 Citations (Scopus) -
Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells
Lopez Pelaez, M., Lamont, D. J., Peggie, M., Shpiro, N., Gray, N. S. & Cohen, P. (Lead / Corresponding author), 9 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 49, p. 17432-17437 6 p.Research output: Contribution to journal › Article › peer-review
87 Citations (Scopus) -
The TLR and IL-1 signalling network at a glance
Cohen, P., Jun 2014, In: Journal of Cell Science. 127, 11, p. 2383-2390 8 p.Research output: Contribution to journal › Article › peer-review
153 Citations (Scopus) -
2013
ABIN1 dysfunction as a genetic basis for lupus nephritis
Caster, D. J., Korte, E. A., Nanda, S. K., McLeish, K. R., Oliver, R. K., G'Sell, R. T., Sheehan, R. M., Freeman, D. W., Coventry, S. C., Kelly, J. A., Guthridge, J. M., James, J. A., Sivils, K. L., Alarcon-Riquelme, M. E., Scofield, R. H., Adrianto, I., Gaffney, P. M., Stevens, A. M., Freedman, B. I. & Langefeld, C. D. & 25 others, , 1 Nov 2013, In: Journal of the American Society of Nephrology. 24, 11, p. 1743-1754 12 p.Research output: Contribution to journal › Article › peer-review
Open Access71 Citations (Scopus) -
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
Emmerich, C. H., Ordureau, A., Strickson, S., Arthur, J. S. C., Pedrioli, P. G. A., Komander, D. & Cohen, P. (Lead / Corresponding author), 17 Sept 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 38, p. 15247-15252 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile365 Citations (Scopus)225 Downloads (Pure) -
DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA
Ordureau, A., Enesa, K., Nanda, S., Le Francois, B., Peggie, M., Prescott, A., Albert, P. R. & Cohen, P., 23 Aug 2013, In: Journal of Biological Chemistry. 288, 34, p. 24569-24580 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (Scopus)213 Downloads (Pure) -
Kinase drug discovery: What's next in the field?
Cohen, P. & Alessi, D. R., 2013, In: ACS Chemical Biology. 8, 1, p. 96-104 9 p.Research output: Contribution to journal › Article › peer-review
334 Citations (Scopus) -
Molecular control of the NEMO family of ubiquitin-binding proteins
Clark, K., Nanda, S. & Cohen, P., 2013, In: Nature Reviews Molecular Cell Biology. 14, p. 673-685 13 p.Research output: Contribution to journal › Article › peer-review
99 Citations (Scopus) -
The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases
Krishnan, N., Bencze, G., Cohen, P. & Tonks, N. K., 2013, In: FEBS Journal. 280, 12, p. 2830-2841 12 p.Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system
Strickson, S., Campbell, D. G., Emmerich, C. H., Knebel, A., Plater, L., Ritorto, M. S., Shpiro, N. & Cohen, P., 1 May 2013, In: Biochemical Journal. 451, 3, p. 427-437 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile170 Citations (Scopus)220 Downloads (Pure) -
Two Phases of Inflammatory Mediator Production Defined by the Study of IRAK2 and IRAK1 Knock-in Mice
Pauls, E., Nanda, S. K., Smith, H., Toth, R., Arthur, J. S. C. & Cohen, P. (Lead / Corresponding author), 2013, In: Journal of Immunology. 1203268.Research output: Contribution to journal › Article › peer-review
81 Citations (Scopus)