Establishing the Basis for Selectivity in the SUMO Spray (Investigator Award)

Project Details

StatusActive
Effective start/end date1/02/2031/01/25

Funding

  • Wellcome Trust (217196/Z/19/Z): £1,947,516.00

Research Output

Antibody RING-Mediated Destruction of Endogenous Proteins

Ibrahim, A. F. M., Shen, L., Tatham, M. H., Dickerson, D., Prescott, A. R., Abidi, N., Xirodimas, D. P. & Hay, R. T., 2 Jul 2020, In : Molecular Cell. 79, 1, p. 155-166 12 p.

Research output: Contribution to journalArticle

Open Access
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    Downregulation of Keap1 confers features of a fasted metabolic state

    Knatko, E. V., Tatham, M. H., Zhang, Y., Castro, C., Higgins, M., Dayalan Naidu, S., Leonardi, C., de la Vega, L., Honda, T., Griffin, J. L., Hay, R. T. & Dinkova-Kostova, A. T., Oct 2020, In : iScience. 23, 10, p. 1-48 48 p., 101638.

    Research output: Contribution to journalArticle

    Open Access
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    Ubiquitin transfer by a RING E3 ligase occurs from a closed E2~ubiquitin conformation

    Branigan, E., Penedo, J. C. & Hay, R., 5 Jun 2020, In : Nature Communications. 11, 11 p., 2846.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)
    16 Downloads (Pure)