Research output per year
Research output per year
Project Details
| Status | Active |
|---|---|
| Effective start/end date | 1/02/20 → 31/01/27 |
Funding
- Wellcome Trust (217196/Z/19/Z): £1,947,516.00
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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Research output
- 13 Article
-
PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways
Jaffray, E., Tatham, M. H., Mojsa, B., Plechanovova, A., Rojas-Fernandez, A., Liu, J. C. Y., Mailand, N., Ibrahim, A. F. M., Ball, G., Porter, I. M. & Hay, R. T. (Lead / Corresponding author), 2 Jun 2025, In: Journal of Cell Biology. 224, 6, p. 1-24 33 p., e202407133.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
Liu, J. C. Y., Ackermann, L., Hoffmann, S., Gál, Z., Hendriks, I. A., Jain, C., Morlot, L., Tatham, M. H., McLelland, G. L., Hay, R. T., Nielsen, M. L., Brummelkamp, T., Haahr, P. (Lead / Corresponding author) & Mailand, N. (Lead / Corresponding author), Sept 2024, In: Nature Structural and Molecular Biology. 31, 9, p. 1355-1367 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)114 Downloads (Pure) -
Mechanism of degrader-targeted protein ubiquitinability
Crowe, C., Nakasone, M., Chandler, S., Craigon, C., Sathe, G., Tatham, M., Makukhin, N., Hay, R. & Ciulli, A. (Lead / Corresponding author), 11 Oct 2024, In: Science Advances. 10, 41, 21 p., eado6492.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)64 Downloads (Pure)