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Establishing the Basis for Selectivity in the SUMO Spray (Investigator Award)
Hay, Ronald
(Investigator)
Gene Regulation and Expression
Overview
Research Outputs
(3)
Project Details
Status
Active
Effective start/end date
1/02/20
→
31/01/25
Funding
Wellcome Trust
(217196/Z/19/Z):
£1,947,516.00
View all
View less
Research output
Research output per year
2020
2020
3
Article
Research output per year
Research output per year
Antibody RING-Mediated Destruction of Endogenous Proteins
Ibrahim, A. F. M.
,
Shen, L.
,
Tatham, M. H.
,
Dickerson, D.
,
Prescott, A. R.
, Abidi, N., Xirodimas, D. P. &
Hay, R. T.
,
2 Jul 2020
,
In:
Molecular Cell.
79
,
1
,
p. 155-166
12 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Single-Domain Antibodies
Antibodies
Proteins
Ubiquitin-Protein Ligases
Proteasome Endopeptidase Complex
45
Downloads (Pure)
Downregulation of Keap1 confers features of a fasted metabolic state
Knatko, E. V.
,
Tatham, M. H.
,
Zhang, Y.
, Castro, C., Higgins, M.,
Dayalan Naidu, S.
, Leonardi, C.,
de la Vega, L.
, Honda, T., Griffin, J. L.,
Hay, R. T.
&
Dinkova-Kostova, A. T.
,
23 Oct 2020
,
In:
iScience.
23
,
10
,
48 p.
, 101638.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Kelch-Like ECH-Associated Protein 1
Mouse Keap1 protein
Down-Regulation
Oxidation-Reduction
NF-E2 Transcription Factor
1
Citation (Scopus)
25
Downloads (Pure)
Ubiquitin transfer by a RING E3 ligase occurs from a closed E2~ubiquitin conformation
Branigan, E.
, Penedo, J. C. &
Hay, R.
,
5 Jun 2020
,
In:
Nature Communications.
11
,
11 p.
, 2846.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Conformations
Ubiquitin-Protein Ligases
Ubiquitin
Forster resonance energy transfer
nucleophiles
5
Citations (Scopus)
41
Downloads (Pure)