Keyphrases
Catalytic Mechanism
66%
Riboswitch
55%
Pseudoknot
38%
Folding Dynamics
33%
Computational Enzymology
33%
Pistol Ribozyme
33%
Hammerhead Ribozyme
33%
Single Molecule Level
33%
O6-methylguanine
33%
Escherichia Coli
33%
Methyltransferase
33%
Ribozyme
33%
PH Dependence
33%
Alkyltransferase
33%
Hammerhead
22%
Thiamine Pyrophosphate Riboswitch
22%
Free Energy Simulation
22%
Quantum Mechanical
22%
Alchemical Free Energy
22%
Arabidopsis
22%
General Acid
22%
Magnesium Ion
22%
Helix
15%
Co-transcriptional Folding
14%
Alkyl Transfer
11%
Thiamine Pyrophosphate
11%
Solution Mechanism
11%
Mechanical Simulation
11%
Stepwise Mechanism
11%
Mechanical Free Energy
11%
Classical Molecular Dynamics
11%
Overall Structure
11%
Nucleophilic Attack
11%
Enhanced Activity
11%
Secondary Structure
11%
Cleavage Site
11%
Sodium Ion
11%
Hydrogen Bonding Interaction
11%
Methyl Transfer
11%
Chimera
11%
Divalent Ions
11%
Intrinsic Rate of Increase
11%
PH Profile
11%
Helical Junction
11%
RNA-based
11%
Rate-controlling
11%
Atomic Level
11%
RNA World
11%
Apparent pKa
11%
Sequence Information
11%
X-ray Crystallography
11%
Kink-turn
11%
Transition State
11%
Proton Transfer
11%
High-resolution Crystal Structure
11%
Hydrogen Bonds (H-bonds)
11%
Design Principles
11%
Biochemical Tools
11%
Protonation
11%
Monovalent Ions
11%
Metal Ions
11%
Local Structure
11%
Leaving Group
11%
Atomic mutagenesis
11%
C-N Bond Formation
11%
PH-independent
11%
Conformational Landscape
9%
Ligand-induced Conformational Changes
9%
Biochemistry, Genetics and Molecular Biology
Ribozyme
100%
Riboswitch
66%
Catalytic Mechanism
66%
RNA
41%
Pseudoknot
38%
Folding Dynamics
33%
Enzymology
33%
Methyltransferase
33%
6-O-Methylguanine
33%
Protonation
33%
Transferase
33%
Escherichia coli
25%
Thiamine Pyrophosphate
25%
Conformation
23%
Adenine
22%
Proton Transport
22%
Crystal Structure
16%
Arabidopsis
16%
Ab-Initio Molecular Dynamics
11%
Hydrogen Bond
11%
Solution and Solubility
11%
Cytosine
11%
Mutagenesis
11%
Nucleotide
11%
Conformational Change
9%
X-Ray Crystallography
8%
Nucleophilicity
5%
Protein Secondary Structure
5%