Research output per year
Research output per year
- 45 results
Search results
-
2020
Human ANKLE1 is a nuclease specific for branched DNA
Song, J., Freeman, A. D. J., Knebel, A., Gartner, A. & Lilley, D. M. J. (Lead / Corresponding author), 2 Oct 2020, In: Journal of Molecular Biology. 432, 21, p. 5825-5834 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)112 Downloads (Pure) -
Structure and ligand binding of the ADP-binding domain of the NAD+ riboswitch
Huang, L., Wang, J. & Lilley, D. M. J. (Lead / Corresponding author), Jul 2020, In: RNA: a Publication of the RNA Society. 26, 7, p. 878-887 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)99 Downloads (Pure) -
2019
Classification of the nucleolytic ribozymes based upon catalytic mechanism
Lilley, D. M. J. (Lead / Corresponding author), 19 Aug 2019, In: F1000Research. 8, 10 p., 1462.Research output: Contribution to journal › Review article › peer-review
Open AccessFile34 Citations (Scopus)161 Downloads (Pure) -
Comparison of the Structures and Mechanisms of the Pistol and Hammerhead Ribozymes
Wilson, T. J., Liu, Y., Li, N.-S., Dai, Q., Piccirilli, J. A. & Lilley, D. M. J. (Lead / Corresponding author), 15 May 2019, In: Journal of the American Chemical Society. 141, 19, p. 7865-7875 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile46 Citations (Scopus)193 Downloads (Pure) -
Effect of methylation of adenine N6 on kink turn structure depends on location
Ashraf, S., Huang, L. & Lilley, D. (Lead / Corresponding author), 2019, In: RNA Biology. 16, 10, p. 1377-1385 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)151 Downloads (Pure) -
Junction resolving enzymes use multivalency to keep the Holliday junction dynamic
Zhou, R. (Lead / Corresponding author), Yang, O., Declais, A.-C., Jin, H., Gwon, G. H., Freeman, A., Cho, Y., Lilley, D. & Ha, T. (Lead / Corresponding author), 1 Mar 2019, In: Nature Chemical Biology. 15, 3, p. 269-275 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)178 Downloads (Pure) -
Structure-guided design of a high affinity ligand for a riboswitch
Huang, L., Wang, J., Wilson, T. & Lilley, D. (Lead / Corresponding author), Apr 2019, In: RNA: a Publication of the RNA Society. 25, 4, p. 423-430 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)216 Downloads (Pure) -
The role of RNA structure in translational regulation by L7Ae protein in archaea
Huang, L., Ashraf, S. & Lilley, D. M. J. (Lead / Corresponding author), Jan 2019, In: RNA: a Publication of the RNA Society. 25, 1, p. 60-69 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)202 Downloads (Pure) -
2018
A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1
Liu, Y., Freeman, A. D. J., Déclais, A.-C. & Lilley, D. M. J. (Lead / Corresponding author), 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 11089-11098 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)184 Downloads (Pure) -
Structure and ligand binding of the SAM-V riboswitch
Huang, L. & Lilley, D. M. J. (Lead / Corresponding author), 27 Jul 2018, In: Nucleic Acids Research. 46, 13, p. 6869-6879 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Citations (Scopus)185 Downloads (Pure) -
2017
Control of box C/D snoRNP assembly by N6-methylation of adenine
Huang, L., Ashraf, S., Wang, J. & Lilley, D. M. J. (Lead / Corresponding author), 1 Sept 2017, In: EMBO Reports. 18, 9, p. 1473-1671 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)239 Downloads (Pure) -
Crystal structures of cyanine fluorophores stacked onto the end of double-stranded RNA
Liu, Y. & Lilley, D. M. J. (Lead / Corresponding author), 5 Dec 2017, In: Biophysical Journal. 113, 11, p. 2236-2343 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)232 Downloads (Pure) -
Fluorescent RNA cytosine analogue - an internal probe for detailed structure and dynamics investigations
Füchtbauer, A. F., Preus, S., Börjesson, K., McPhee, S. A., Lilley, D. M. J. & Wilhelmsson, L. M. (Lead / Corresponding author), 24 May 2017, In: Scientific Reports. 7, p. 1-8 8 p., 2393.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus)209 Downloads (Pure) -
Holliday junction-resolving enzymes - structures and mechanisms
Lilley, D. M. J. (Lead / Corresponding author), Apr 2017, In: FEBS Letters. 591, 8, p. 1073-1082 10 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile23 Citations (Scopus)333 Downloads (Pure) -
How RNA acts as a nuclease: some mechanistic comparisons in the nucleolytic ribozymes
Lilley, D. M. J. (Lead / Corresponding author), 15 Jun 2017, In: Biochemical Society Transactions. 45, 3, p. 683-691 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile31 Citations (Scopus)1010 Downloads (Pure) -
Sequence determinants of the folding properties of box C/D kink-turns in RNA
Ashraf, S., Huang, L. & Lilley, D. M. J. (Lead / Corresponding author), Dec 2017, In: RNA: a Publication of the RNA Society. 23, 12, p. 1927-1935 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)182 Downloads (Pure) -
The Guanidine Riboswitch-A Poor Orphan No Longer
Lilley, D. M. J. (Lead / Corresponding author), 16 Feb 2017, In: Cell Chemical Biology. 24, 2, p. 130-131 2 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Citations (Scopus) -
The structure of a nucleolytic ribozyme that employs a catalytic metal ion
Liu, Y., Wilson, T. & Lilley, D. (Lead / Corresponding author), May 2017, In: Nature Chemical Biology. 13, 5, p. 508-513 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile48 Citations (Scopus)356 Downloads (Pure) -
The structure of the Guanidine-III Riboswitch
Huang, L., Wang, J., Wilson, T. J. & Lilley, D. M. J. (Lead / Corresponding author), 16 Nov 2017, In: Cell Chemical Biology. 24, 11, p. 1407-1415.e2 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Citations (Scopus)227 Downloads (Pure) -
The Structure of the Guanidine-II Riboswitch
Huang, L., Wang, J. & Lilley, D. M. J. (Lead / Corresponding author), 22 Jun 2017, In: Cell Chemical Biology. 24, 6, p. 695-702.e2 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile54 Citations (Scopus)219 Downloads (Pure) -
2016
A critical base pair in k-turns determines the conformational class adopted, and correlates with biological function
Huang, L., Wang, J. & Lilley, D. M. J. (Lead / Corresponding author), 20 Jun 2016, In: Nucleic Acids Research. 44, 11, p. 5390-5398 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)361 Downloads (Pure) -
Analysis of the Intrinsically Disordered N-Terminus of the DNA Junction-Resolving Enzyme T7 Endonuclease I: Identification of Structure Formed upon DNA Binding
Freeman, A. D. J., Stevens, M., Declais, A. C., Leahy, A., Mackay, K., El Mkami, H., Lilley, D. M. J. & Norman, D. G. (Lead / Corresponding author), 2 Aug 2016, In: Biochemistry. 55, 30, p. 4166-4172 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)204 Downloads (Pure) -
A quasi-cyclic RNA nano-scale molecular object constructed using kink turns
Huang, L. & Lilley, D. M. J. (Lead / Corresponding author), 7 Sept 2016, In: Nanoscale. 8, 33, p. 15189-15195 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)200 Downloads (Pure) -
Editorial overview: Nucleic acids and their protein complexes
Lilley, D. M. J. (Lead / Corresponding author) & Pyle, A. M. (Lead / Corresponding author), 2016, In: Current Opinion in Structural Biology. 36, p. vii-viii 2 p.Research output: Contribution to journal › Editorial › peer-review
1 Citation (Scopus) -
The Kink Turn, a Key Architectural Element in RNA Structure
Huang, L. & Lilley, D. M. J. (Lead / Corresponding author), 27 Feb 2016, In: Journal of Molecular Biology. 428, 5, p. 790-801 12 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile42 Citations (Scopus)150 Downloads (Pure) -
The Novel Chemical Mechanism of the Twister Ribozyme
Wilson, T. J., Liu, Y., Domnick, C., Kath-Schorr, S. & Lilley, D. M. J. (Lead / Corresponding author), 18 May 2016, In: Journal of the American Chemical Society. 138, 19, p. 6151-6162 12 p.Research output: Contribution to journal › Article › peer-review
62 Citations (Scopus) -
The solution structural ensembles of RNA kink-turn motifs and their protein complexes
Shi, X. (Lead / Corresponding author), Huang, L., Lilley, D. M. J., Harbury, P. B. (Lead / Corresponding author) & Herschlag, D. (Lead / Corresponding author), Mar 2016, In: Nature Chemical Biology. 12, 3, p. 146-152 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)212 Downloads (Pure) -
2015
RNA catalysis-is that it?
Wilson, T. J. & Lilley, D. M. J. (Lead / Corresponding author), Apr 2015, In: RNA: a Publication of the RNA Society. 21, 4, p. 534-537 4 p.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
2014
Crystal structure and mechanistic investigation of the twister ribozyme
Liu, Y., Wilson, T. J., McPhee, S. A. & Lilley, D. M. J. (Lead / Corresponding author), Sept 2014, In: Nature Chemical Biology. 10, 9, p. 739-744 6 p.Research output: Contribution to journal › Article › peer-review
108 Citations (Scopus) -
FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain
Pennell, S. (Lead / Corresponding author), Déclais, A.-C., Li, J., Haire, L. F., Berg, W., Saldanha, J. W., Taylor, I. A., Rouse, J., Lilley, D. M. J. & Smerdon, S. J., 10 Jul 2014, In: Cell Reports. 8, 1, p. 84-93 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus)241 Downloads (Pure) -
GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes
Freeman, A. D. J., Liu, Y., Déclais, A.-C., Gartner, A. & Lilley, D. M. J. (Lead / Corresponding author), 12 Dec 2014, In: Journal of Molecular Biology. 426, 24, p. 3946-3959 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)250 Downloads (Pure) -
Structure of a rare non-standard sequence k-turn bound by L7Ae protein
Huang, L. & Lilley, D. M. J. (Lead / Corresponding author), Apr 2014, In: Nucleic Acids Research. 42, 7, p. 4734-4740 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)231 Downloads (Pure) -
The k-junction motif in RNA structure
Wang, J., Daldrop, P., Huang, L. & Lilley, D. M. J. (Lead / Corresponding author), Apr 2014, In: Nucleic Acids Research. 42, 8, p. 5322-5331 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)372 Downloads (Pure) -
The K-turn motif in riboswitches and other RNA species
Lilley, D. M. J. (Lead / Corresponding author), Oct 2014, In: BBA - Gene Regulatory Mechanisms. 1839, 10, p. 995-1004 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)255 Downloads (Pure) -
2013
A mechanistic comparison of the varkud satellite and hairpin ribozymes
Wilson, T. J. & Lilley, D. M. J., 2013, Catalytic RNA. Soukup, G. A. (ed.). London: Academic Press, p. 93-121 29 p. (Progress in molecular biology and translational science; vol. 120).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Citations (Scopus) -
Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases
Castor, D., Nair, N., Déclais, A.-C., Lachaud, C., Toth, R., Macartney, T. J., Lilley, D. M. J., Arthur, J. S. C. & Rouse, J. (Lead / Corresponding author), 24 Oct 2013, In: Molecular Cell. 52, 2, p. 221-233 13 p.Research output: Contribution to journal › Article
121 Citations (Scopus) -
Measurement of the Change in Twist at a Helical Junction in RNA Using the Orientation Dependence of FRET
Fessl, T. & Lilley, D. M. J., 5 Nov 2013, In: Biophysical Journal. 105, 9, p. 2175-2181 7 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
The importance of the N-terminus of T7 endonuclease I in the interaction with DNA junctions
Freeman, A. D. J., Déclais, A.-C. & Lilley, D. M. J., 23 Jan 2013, In: Journal of Molecular Biology. 425, 2, p. 395-410 16 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
The molecular recognition of kink-turn structure by the L7Ae class of proteins
Huang, L. & Lilley, D. M. J. (Lead / Corresponding author), Dec 2013, In: RNA. 19, 12, p. 1703-1710 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile52 Citations (Scopus)156 Downloads (Pure) -
The plasticity of a structural motif in RNA: Structural polymorphism of a kink turn as a function of its environment
Daldrop, P. & Lilley, D. M. J., 2013, In: RNA: a Publication of the RNA Society. 19, 3, p. 357-364 8 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
2012
General Acid–Base Catalysis Mediated by Nucleobases in the Hairpin Ribozyme
Kath-Schorr, S., Wilson, T. J., Li, N. S., Lu, J., Piccirilli, J. A. & Lilley, D. M. J., 10 Oct 2012, In: Journal of the American Chemical Society. 134, 40, p. 16717-16724 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile77 Citations (Scopus)284 Downloads (Pure) -
Single-molecule observation of the induction of k-turn RNA structure on binding L7Ae protein
Wang, J., Fessl, T., Schroeder, K. T., Ouellet, J., Liu, Y., Freeman, A. D. J. & Lilley, D. M. J. (Lead / Corresponding author), 19 Dec 2012, In: Biophysical Journal. 103, 12, p. 2541-2548 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)134 Downloads (Pure) -
Synthesis of novel tetrazole C5-linked C0- and C2-ribonucleoside phosphoramidites using MePOM and POM groups for probing RNA catalysis
Harusawa, S., Yoneyama, H., Fujisue, D., Nishiura, M., Fujitake, M., Usami, Y., Zhao, Z.-Y., Mcphee, S. A., Wilson, T. J. & Lilley, D. M. J., 2012, In: Tetrahedron Letters. 53, 44, p. 5891-5894 4 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
The structure and folding of kink turns in RNA
Lilley, D. M. J., 2012, In: Wiley Interdisciplinary Reviews: RNA. 3, 6, p. 797-805 9 p.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
The Structure of Sulfoindocarbocyanine 3 Terminally Attached to dsDNA via a Long, Flexible Tether
Urnavicius, L., McPhee, S. A., Lilley, D. M. J. & Norman, D. G., 8 Feb 2012, In: Biophysical Journal. 102, 3, p. 561-568 8 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus)