Research output per year
Research output per year
- 14 results
Search results
-
2025
Recombinant production platform for Group A Streptococcus glycoconjugate vaccines
Ajay Castro, S., Passmore, I. J., Ndeh, D., Shaw, H. A., Rudas, A., Burns, K., Thomson, S., Nagar, R., Alagesan, K., Reglinski, M., Lucas, K., Abouelhadid, S., Schwarz-Linek, U., Mawas, F., Widmalm, G., Wren, B. W. (Lead / Corresponding author) & Dorfmueller, H. C. (Lead / Corresponding author), Dec 2025, In: NPJ Vaccines. 10, 1, 14 p., 16.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)15 Downloads (Pure) -
Rhamnose polysaccharide-decorated outer membrane vesicles as a vaccine candidate targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis
Ajay Castro, S., Thomson, S., Shaw, H. A., Zorzoli, A., Meyer, B. H., Reglinski, M., McNeil, M. & Dorfmueller, H. C. (Lead / Corresponding author), Aug 2025, In: Vaccine. 25, 11 p., 100676.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
2023
Bioinformatics characterization of BcsA-like orphan proteins suggest they form a novel family of pseudomonad cyclic-β-glucan synthases
Spiers, A. J. (Lead / Corresponding author), Dorfmueller, H. C., Jerdan, R., McGregor, J., Nicoll, A., Steel, K. & Cameron, S., 2 Jun 2023, In: PLoS ONE. 18, 6, 32 p., e0286540.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)79 Downloads (Pure) -
Genomic diversity in Fructobacillus spp. isolated from fructose-rich niches
Mohamed, F., Ruiz Rodriguez, L. G., Zorzoli, A., Dorfmueller, H., Raya, R. R. (Lead / Corresponding author) & Mozzi, F. (Lead / Corresponding author), 16 Feb 2023, In: PLoS ONE. 18, 2, 25 p., e0281839.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)125 Downloads (Pure) -
2022
Agl24 is an ancient archaeal homolog of the eukaryotic N-glycan chitobiose synthesis enzymes
Meyer, B. H. (Lead / Corresponding author), Adam, P. S., Wagstaff, B., Kolyfetis, G. E., Probst, A. J., Albers, S. V. & Dorfmueller, H. (Lead / Corresponding author), 8 Apr 2022, In: eLife. 11, 27 p., e67448.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)126 Downloads (Pure) -
2021
A brief review on Group A Streptococcus pathogenesis and vaccine development
Castro, S. A. & Dorfmueller, H. C. (Lead / Corresponding author), 10 Mar 2021, In: Royal Society Open Science. 8, 3, 17 p., 201991.Research output: Contribution to journal › Review article › peer-review
Open AccessFile55 Citations (Scopus)633 Downloads (Pure) -
Examining the distribution and impact of single nucleotide polymorphisms in the capsular locus of Streptococcus pneumoniae serotype 19A
Arends, D. W., Miellet, W. R., Langereis, J. D., Ederveen, T. H. A., van der Gaast-de Jongh, C. E., van Scherpenzeel, M., Knol, M. J., van Sorge, N. M., Lefeber, D. J., Trzciński, K., Sanders, E. A. M., Dorfmueller, H. C., Bootsma, H. J. & de Jonge, M. I. (Lead / Corresponding author), 15 Oct 2021, In: Infection and Immunity. 89, 11, 14 p., e00246-21.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)134 Downloads (Pure) -
Modification of cell wall polysaccharide guides cell division in Streptococcus mutans
Zamakhaeva, S., Chaton, C. T., Rush, J. S., Ajay Castro, S., Kenner, C. W., Yarawsky, A. E., Herr, A. B., van Sorge, N. M., Dorfmueller, H. C., Frolenkov, G. I., Korotkov, K. V. & Korotkova, N. (Lead / Corresponding author), Aug 2021, In: Nature Chemical Biology. 17, p. 878-887 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)755 Downloads (Pure) -
Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin
King, H., Ajay Castro, S., Pohane, A. A., Scholte, C. M., Fischetti, V. A., Korotkova, N., Nelson, D. C. & Dorfmueller, H. C. (Lead / Corresponding author), 25 Jun 2021, In: Biochemical Journal. 478, 12, p. 2385-2397 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)166 Downloads (Pure) -
NDP-rhamnose biosynthesis and rhamnosyltransferases: building diverse glycoconjugates in nature
Wagstaff, B. A., Zorzoli, A. & Dorfmueller, H. C. (Lead / Corresponding author), Feb 2021, In: Biochemical Journal. 478, 4, p. 685-701 17 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile18 Citations (Scopus)680 Downloads (Pure) -
2020
Scalar nanostructure of the Candida albicans cell wall; a molecular, cellular and ultrastructural analysis and interpretation
Lenardon, M. D. (Lead / Corresponding author), Sood, P., Dorfmueller, H. C., Brown, A. J. P. & Gow, N. A. R. (Lead / Corresponding author), Dec 2020, In: Cell Surface. 6, 16 p., 100047.Research output: Contribution to journal › Article › peer-review
Open AccessFile62 Citations (Scopus)396 Downloads (Pure) -
2019
Discovery of an RmlC/D fusion protein in the microalga Prymnesium parvum and its implications for NDP-β-L-rhamnose biosynthesis in microalgae
Wagstaff, B., Rejzek, M., Kuhaudomlarp, S., Hill, L., Mascia, I., Nepogodiev, S. A., Dorfmueller, H. & Field, R. A. (Lead / Corresponding author), 7 Jun 2019, In: Journal of Biological Chemistry. 294, 23, p. 9172-9185 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)404 Downloads (Pure) -
Group A, B, C, and G Streptococcus Lancefield antigen biosynthesis is initiated by a conserved α-D-GlcNAc-β-1,4-L-rhamnosyltransferase
Zorzoli, A., Meyer, B. H., Adair, E., Torgov, V. I., Veselovsky, V. V., Danilov, L. L., Uhrin, D. & Dorfmueller, H. C. (Lead / Corresponding author), 18 Oct 2019, In: Journal of Biological Chemistry. 294, 42, p. 15237-15256 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)395 Downloads (Pure) -
Streptococcal dTDP-L-rhamnose biosynthesis enzymes: functional characterization and lead compound identification
van der Beek, S. L., Zorzoli, A., Çanak, E., Chapman, R. N., Lucas, K., Meyer, B. H., Evangelopoulos, D., de Carvalho, L. P. S., Boons, G.-J., Dorfmueller, H. C. (Lead / Corresponding author) & van Sorge, N. M. (Lead / Corresponding author), Apr 2019, In: Molecular Microbiology. 111, 4, p. 951-964 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Citations (Scopus)460 Downloads (Pure)