Research output per year
Research output per year
- 17 results
Search results
-
2024
A CDK1 phosphorylation site on Drosophila PAR-3 regulates neuroblast polarisation and sensory organ formation
Loyer, N., Hogg, E. K. J., Shaw, H. G., Pasztor, A., Murray, D. H., Findlay, G. M. & Januschke, J. (Lead / Corresponding author), 1 Jul 2024, In: eLife. 13, 28 p., e97902.Research output: Contribution to journal › Article › peer-review
Open AccessFile88 Downloads (Pure) -
Chromatin targeting of the RNF12/RLIM E3 ubiquitin ligase controls transcriptional responses
Espejo-Serrano, C., Aitken, C., Tan, B. F., May, D. G., Chrisopulos, R. J., Roux, K. J., Demmers, J. A. A., Mackintosh, S. G., Gribnau, J., Bustos, F., Gontan, C. & Findlay, G. M. (Lead / Corresponding author), Mar 2024, In: Life Science Alliance. 7, 3, 19 p., e202302282.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)90 Downloads (Pure) -
2023
Functions of SRPK, CLK and DYRK kinases in stem cells, development, and human developmental disorders
Hogg, E. K. J. & Findlay, G. M. (Lead / Corresponding author), Oct 2023, In: FEBS Letters. 597, 19, p. 2375-2415 41 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Citations (Scopus)111 Downloads (Pure) -
Roles of the Rlim-Rex1 axis during X chromosome inactivation in mice
Wang, F., Chander, A., Yoon, Y., Welton, J. M., Wallingford, M. C., Espejo-Serrano, C., Bustos, F., Findlay, G. M., Mager, J. & Bach, I. (Lead / Corresponding author), 26 Dec 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 52, 8 p., e2313200120.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)69 Downloads (Pure) -
Therapeutic validation and targeting of signalling networks that are dysregulated in intellectual disability
Bustos, F. (Lead / Corresponding author) & Findlay, G. M. (Lead / Corresponding author), Mar 2023, In: FEBS Journal. 290, 6, p. 1454-1460 7 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile95 Downloads (Pure) -
2022
Activity-Based Probe Profiling of RNF12 E3 Ubiquitin Ligase Function in Tonne-Kalscheuer Syndrome
Bustos, F., Mathur, S., Espejo-Serrano, C., Toth, R., Hastie, C. J., Virdee, S. (Lead / Corresponding author) & Findlay, G. M. (Lead / Corresponding author), Nov 2022, In: Life Science Alliance. 5, 11, 12 p., e202101248.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)93 Downloads (Pure) -
An RNF12-USP26 amplification loop drives germ cell specification and is disrupted by disease-associated mutations
Segarra Fas, A., Espejo Serrano, C., Bustos, F., Zhou, H., Wang, F., Toth, R., Macartney, T., Bach, I., Nardocci, G. & Findlay, G. (Lead / Corresponding author), 12 Jul 2022, In: Science Signaling. 15, 742, 16 p., eabm5995.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)592 Downloads (Pure) -
Disease insights from stem cells
Findlay, G. (Contributing member), Hogg, E. (Contributing member), Espejo Serrano, C. (Contributing member), Cameron, A. (Producer) & Soave, S. (Film-maker), 13 Sept 2022Research output: Non-textual form › Digital or Visual Products
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2021
An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells
Brown, H. A., Williams, C. A. C., Zhou, H., Rios-Szwed, D., Fernandez-Alonso, R., Mansoor, S., McMulkin, L., Toth, R., Gourlay, R., Peltier, J., Dieguez-Martinez, N., Trost, M., Lizcano, J. M., Stavridis, M. P. & Findlay, G. M. (Lead / Corresponding author), 6 Dec 2021, In: Biochemical Journal. 478, 23, p. 4119-4136 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)151 Downloads (Pure) -
A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne-Kalscheuer syndrome
Bustos, F., Espejo-Serrano, C., Segarra-Fas, A., Toth, R., Eaton, A. J., Kernohan, K. D., Wilson, M. J., Riley, L. G. (Lead / Corresponding author) & Findlay, G. M. (Lead / Corresponding author), 5 May 2021, In: Scientific Reports. 11, 9 p., 9560.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)165 Downloads (Pure) -
LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain
Cornejo, F., Cortés, B. I., Findlay, G. M. & Cancino, G. I. (Lead / Corresponding author), 13 Dec 2021, In: Frontiers in Cell and Developmental Biology. 9, 21 p., 659951.Research output: Contribution to journal › Review article › peer-review
Open AccessFile22 Citations (Scopus)257 Downloads (Pure) -
Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self-renewal
Mullin, N. P., Varghese, J., Colby, D., Richardson, J. M., Findlay, G. M. & Chambers, I. (Lead / Corresponding author), Jan 2021, In: FEBS Letters. 595, 1, p. 14-25 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)72 Downloads (Pure) -
2020
A RNF12-USP26 amplification loop promotes germ cell specification and is disrupted in urogenital disorders
Segarra-Fas, A., Bustos, F., Nardocci, G. & Findlay, G. M. (Lead / Corresponding author), 16 Nov 2020, BioRxiv, p. 1-31, 31 p.Research output: Working paper/Preprint › Preprint
Open Access -
Functional diversification of SRSF protein kinase to control ubiquitin-dependent neurodevelopmental signalling
Bustos, F., Segarra-Fas, A., Nardocci, G., Cassidy, A., Antico, O., Davidson, L., Brandenburg, L., Macartney, T., Toth, R., Hastie, C. J., Moran, J., Gourlay, R., Vargese, J., Soares, R., Montecino, M. & Findlay, G. M. (Lead / Corresponding author), 7 Dec 2020, In: Developmental Cell. 55, p. 629-647.e7 27 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)189 Downloads (Pure) -
Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation
Fernandez-Alonso, R., Bustos, F., Budzyk, M., Kumar, P., Helbig, A. O., Hukelmann, J., Lamond, A. I., Lanner, F., Zhou, H., Petsalaki, E. & Findlay, G. M. (Lead / Corresponding author), 13 Mar 2020, In: Nature Communications. 11, 13 p., 1357.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)188 Downloads (Pure) -
2019
Profiling embryonic stem cell differentiation by MALDI TOF mass spectrometry: development of a reproducible and robust sample preparation workflow
Heap, R. E., Segarra Fas, A., Blain, A. P., Findlay, G. & Trost, M. (Lead / Corresponding author), 7 Nov 2019, In: Analyst. 144, 21, p. 6371-6381 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)138 Downloads (Pure) -
2018
RNF12 X-linked intellectual disability mutations disrupt E3 ligase activity and neural differentiation
Bustos, F., Segarra Fas, A., Chaugule, V. K., Brandenburg, L., Branigan, E., Toth, R., Macartney, T., Knebel, A., Hay, R., Walden, H. & Findlay, G. (Lead / Corresponding author), 8 May 2018, In: Cell Reports. 23, 6, p. 1599-1611 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)490 Downloads (Pure)