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Genetic Structural and Chemical Validation of Aspergillus Fumigatus Cell Wall Targets (Programme Grant)
van Aalten, Daan
(Investigator)
Gene Regulation and Expression
Overview
Research Outputs
(14)
Project Details
Status
Finished
Effective start/end date
1/11/14
→
31/10/19
Funding
Medical Research Council
(MR/M004139/1):
£1,751,714.00
View all
View less
Research Output
Research Output per year
2014
2020
14
Article
Research Output per year
Research Output per year
Targeting a critical step in fungal hexosamine biosynthesis
Lockhart, D.,
Stanley, M.
,
Raimi, O.
,
Robinson, D.
, Boldovjakova, D.,
Squair, D.
, Ferenbach, A., Fang, W. &
van Aalten, D.
,
26 Jun 2020
,
In:
Journal of Biological Chemistry.
295
,
26
,
p. 8678-8691
14 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Biosynthesis
Hexosamines
Cell Wall
Cells
Aspergillus fumigatus
1
Citation (Scopus)
19
Downloads (Pure)
Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases
Fang, W., Sanz, A. B.,
Galan Bartual, S.
, Wang, B., Ferenbach, A., Farkaš, V., Hurtado-Guerrero, R., Arroyo, J. &
van Aalten, D.
,
10 Apr 2019
,
In:
Nature Communications.
10
,
1
,
p. 1-10
10 p.
, 1669.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Aspergillus
redundancy
Aspergillus fumigatus
Cell Wall
Chitin
4
Citations (Scopus)
122
Downloads (Pure)
Evidence for substrate assisted catalysis in
N
-acetylphosphoglucosamine mutase
Raimi, O. G., Hurtado Guerrero, R. &
van Aalten, D. M. F.
,
16 Aug 2018
,
In:
The Biochemical journal.
475
,
15
,
p. 2547-2557
11 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
N-acetylglucosamine 6-phosphate
N-acetylglucosamine-1-phosphate
Biosynthetic Pathways
glucose-1,6-bisphosphate
Intramolecular Transferases
139
Downloads (Pure)