Genetic Structural and Chemical Validation of Aspergillus Fumigatus Cell Wall Targets (Programme Grant)

Project Details

StatusFinished
Effective start/end date1/11/14 → 31/10/19

Funding

  • Medical Research Council (MR/M004139/1): £1,751,714.00
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Research Output

Targeting a critical step in fungal hexosamine biosynthesis

Lockhart, D., Stanley, M., Raimi, O., Robinson, D., Boldovjakova, D., Squair, D., Ferenbach, A., Fang, W. & van Aalten, D., 26 Jun 2020, In : Journal of Biological Chemistry. 295, 26, p. 8678-8691 14 p.

Research output: Contribution to journal › Article

Open Access
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    • 6 Downloads (Pure)

    Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases

    Fang, W., Sanz, A. B., Galan Bartual, S., Wang, B., Ferenbach, A., Farkaš, V., Hurtado-Guerrero, R., Arroyo, J. & van Aalten, D., 10 Apr 2019, In : Nature Communications. 10, 1, p. 1-10 10 p., 1669.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 1 Citation (Scopus)
    104 Downloads (Pure)

    Evidence for substrate assisted catalysis in N-acetylphosphoglucosamine mutase

    Raimi, O. G., Hurtado Guerrero, R. & van Aalten, D. M. F., 16 Aug 2018, In : The Biochemical journal. 475, 15, p. 2547-2557 11 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 117 Downloads (Pure)