Research output per year
Research output per year
Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 1/08/19 → 30/09/21 |
Funding
- (17298): £374,265.00
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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Datasets
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Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain
Khan, S. (Creator), Sobu, Y. (Creator), Pfeffer, S. (Creator), Dhekne, H. (Creator), Tonelli, F. (Creator), Berndsen, K. (Creator) & Alessi, D. (Creator), Dryad, 1 Nov 2021
DOI: 10.5061/dryad.76hdr7sxx, https://datadryad.org/stash/dataset/doi:10.5061/dryad.76hdr7sxx
Dataset
Research output
- 8 Article
-
A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
Vides, E. G., Adhikari, A., Chiang, C. Y., Lis, P., Purlyte, E., Limouse, C., Shumate, J. L., Spínola-Lasso, E., Dhekne, H. S., Alessi, D. R. & Pfeffer, S. R., 23 Sept 2022, In: eLife. 11, 29 p., e79771.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)86 Downloads (Pure) -
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U., Karapetsas, A., Nirujogi, R. S., Mathea, S., Chatterjee, D., Pal, P., Lis, P., Taylor, M., Purlyte, E., Gourlay, R., Dorward, M., Weidlich, S., Toth, R., Polinski, N. K., Knapp, S., Tonelli, F. (Lead / Corresponding author) & Alessi, D. (Lead / Corresponding author), 10 Feb 2021, In: Biochemical Journal. 478, 3, p. 553-578 26 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (Scopus)221 Downloads (Pure) -
Development of a multiplexed targeted mass spectrometry assay for LRRK2-phosphorylated Rabs and Ser910/Ser935 biomarker sites
Nirujogi, R. S. (Lead / Corresponding author), Tonelli, F., Taylor, M., Lis, P., Zimprich, A., Sammler, E. & Alessi, D. R. (Lead / Corresponding author), 22 Jan 2021, In: Biochemical Journal. 478, 2, p. 299-326 28 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)211 Downloads (Pure)