HIPK2 as a Novel Determinant of Tumour Progression and Therapeutic Resistance

Project Details

StatusFinished
Effective start/end date1/02/17 → 1/02/24

Funding

  • Cancer Research UK (C52419/A22869): £687,013.48
  • Cancer Research UK (C52419/A22869): £682,454.00

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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  • Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways

    Kurmasheva, N., Said, A., Wong, B., Kinderman, P., Han, X., Rahimic, A. H. F., Kress, A., Carter-Timofte, M. E., Holm, E., van der Horst, D., Kollmann, C. F., Liu, Z., Wang, C., Hoang, H.-D., Kovalenko, E., Chrysopoulou, M., Twayana, K. S., Ottosen, R. N., Svenningsen, E. B. & Begnini, F. & 30 others, Kiib, A. E., Kromm, F. E. H., Weiss, H. J., Di Carlo, D., Muscolini, M., Higgins, M., van der Heijden, M., Bardoul, A., Tong, T., Ozsvar, A., Hou, W.-H., Schack, V. R., Holm, C. K., Zheng, Y., Ruzek, M., Kalucka, J., de la Vega, L., Elgaher, W. A. M., Korshoej, A. R., Lin, R., Hiscott, J., Poulsen, T. B., O'Neill, L. A., Roy, D. G., Rinschen, M. M., van Montfoort, N., Diallo, J.-S., Farin, H. F., Alain, T. & Olagnier, D. (Lead / Corresponding author), 15 May 2024, In: Nature Communications. 15, 1, 28 p., 4096.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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    3 Citations (Scopus)
    87 Downloads (Pure)

  • Dual inhibition of HSF1 and DYRK2 impedes cancer progression

    Tandon, V., Moreno, R., Allmeroth, K., Quinn, J., Wiley, S. E., Nicely, L. G., Denzel, M. S., Edwards, J., de la Vega, L. & Banerjee, S. (Lead / Corresponding author), Jan 2023, In: Bioscience Reports. 43, 1, 14 p., BSR20222102.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    6 Citations (Scopus)
    83 Downloads (Pure)

  • A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival

    Lara-Chica, M., Correa-Sáez, A., Jiménez-Izquierdo, R., Garrido-Rodríguez, M., Ponce, F. J., Moreno, R., Morrison, K., Di Vona, C., Arató, K., Jiménez-Jiménez, C., Morrugares, R., Schmitz, M. L., de la Luna, S., de la Vega, L. & Calzado, M. A. (Lead / Corresponding author), Jan 2022, In: Cell Death and Differentiation. 29, p. 105-117 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    17 Citations (Scopus)
    105 Downloads (Pure)
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