Research output per year
Research output per year
- 12 results
Search results
-
2024
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Kurmasheva, N., Said, A., Wong, B., Kinderman, P., Han, X., Rahimic, A. H. F., Kress, A., Carter-Timofte, M. E., Holm, E., van der Horst, D., Kollmann, C. F., Liu, Z., Wang, C., Hoang, H.-D., Kovalenko, E., Chrysopoulou, M., Twayana, K. S., Ottosen, R. N., Svenningsen, E. B. & Begnini, F. & 30 others, , 15 May 2024, In: Nature Communications. 15, 1, 28 p., 4096.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)27 Downloads (Pure) -
2023
Dual inhibition of HSF1 and DYRK2 impedes cancer progression
Tandon, V., Moreno, R., Allmeroth, K., Quinn, J., Wiley, S. E., Nicely, L. G., Denzel, M. S., Edwards, J., de la Vega, L. & Banerjee, S. (Lead / Corresponding author), Jan 2023, In: Bioscience Reports. 43, 1, 14 p., BSR20222102.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)75 Downloads (Pure) -
2022
A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival
Lara-Chica, M., Correa-Sáez, A., Jiménez-Izquierdo, R., Garrido-Rodríguez, M., Ponce, F. J., Moreno, R., Morrison, K., Di Vona, C., Arató, K., Jiménez-Jiménez, C., Morrugares, R., Schmitz, M. L., de la Luna, S., de la Vega, L. & Calzado, M. A. (Lead / Corresponding author), Jan 2022, In: Cell Death and Differentiation. 29, p. 105-117 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)84 Downloads (Pure) -
Biotinylation of an acetylenic tricyclic bis(cyanoenone) lowers its potency as an NRF2 activator while creating a novel activity against BACH1
Moreno, R., Casares, L., Higgins, M., Ali, K. X., Honda, T., Wiel, C., Sayin, V. I., Dinkova-Kostova, A. T. & de la Vega, L. (Lead / Corresponding author), 9 Sept 2022, In: Free Radical Biology and Medicine. 191, p. 203-211 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)155 Downloads (Pure) -
The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity
Casares, L., Moreno, R., Ali, K. X., Higgins, M., Dayalan Naidu, S., Neill, G., Cassin, L., Kiib, A. E., Svenningsen, E. B., Minassi, A., Honda, T., Poulsen, T. B., Wiel, C., Sayin, V. I., Dinkova-Kostova, A. T., Olagnier, D. & de la Vega, L. (Lead / Corresponding author), May 2022, In: Redox Biology. 51, 12 p., 102291.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)67 Downloads (Pure) -
2021
Emerging roles of DYRK2 in cancer
Tandon, V., de la Vega, L. & Banerjee, S. (Lead / Corresponding author), 7 Jan 2021, In: Journal of Biological Chemistry. 296, 17 p., 100233.Research output: Contribution to journal › Review article › peer-review
Open AccessFile35 Citations (Scopus)148 Downloads (Pure) -
The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner
Zhang, Y., Gilmour, A., Ahn, Y.-H., de la Vega, L. & Dinkova-Kostova, A. (Lead / Corresponding author), Jun 2021, In: Phytomedicine. 86, 6 p., 153062.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)195 Downloads (Pure) -
The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress
Moreno Dorta, R., Banerjee, S., Jackson, A. W., Quinn, J., Baillie, G., Dixon, J. E., Dinkova-Kostova, A., Edwards, J. & de la Vega, L. (Lead / Corresponding author), May 2021, In: Cell Death & Differentiation. 28, p. 1563-1578 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)100 Downloads (Pure) -
2020
Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1
Casares Perez, L., García, V., Garrido-Rodríguez, M., Millán, E., Collado, J. A., García-Martín, A., Peñarando, J., Calzado, M. A., de la Vega, L. (Lead / Corresponding author) & Muñoz, E. (Lead / Corresponding author), Jan 2020, In: Redox Biology. 28, p. 1-15 15 p., 101321.Research output: Contribution to journal › Article › peer-review
Open AccessFile114 Citations (Scopus)218 Downloads (Pure) -
High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro
Torrente Fernandez, L., Maan, G., Rezig, A. O., Quinn, J., Jackson, A., Grilli, A., Casares, L., Zhang, Y., Kulesskiy, E., Saarela, J., Bicciato, S., Edwards, J., Dinkova-Kostova, A. & de la Vega, L. (Lead / Corresponding author), Oct 2020, In: Biomolecules. 10, 10, 16 p., 1365.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)81 Downloads (Pure) -
Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity
Casares Perez, L., Unciti-Broceta, J. D., Prados, M. E., Caprioglio, D., Mattoteia, D., Higgins, M., Apendino, G., Dinkova-Kostova, A. T., Muñoz, E. & de la Vega, L. (Lead / Corresponding author), Oct 2020, In: Redox Biology. 37, 10 p., 101689.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)109 Downloads (Pure) -
2019
Induction of the Antioxidant Response by the Transcription Factor NRF2 Increases Bioactivation of the Mutagenic Air Pollutant 3-Nitrobenzanthrone in Human Lung Cells
Murray, J. R., de la Vega, L., Hayes, J. D., Duan, L. & Penning, T. M. (Lead / Corresponding author), 16 Dec 2019, In: Chemical Research in Toxicology. 32, 12, p. 2538-2551 14 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus)