Research output per year
Research output per year
Research output
- 5 Article
Search results
-
2024
Multidrug efflux in Gram-negative bacteria: structural modifications in active compounds leading to efflux pump avoidance
Gurvic, D. (Lead / Corresponding author) & Zachariae, U. (Lead / Corresponding author), 16 Mar 2024, In: npj Antimicrobials and Resistance . 2, 11 p., 6.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
2023
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration
Gong, G. Q., Bilanges, B., Allsop, B., Masson, G. R., Roberton, V., Askwith, T., Oxenford, S., Madsen, R. R., Conduit, S. E., Bellini, D., Fitzek, M., Collier, M., Najam, O., He, Z., Wahab, B., McLaughlin, S. H., Chan, A. W. E., Feierberg, I., Madin, A. & Morelli, D. & 21 others, , 1 Jun 2023, In: Nature. 618, p. 159-168 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)183 Downloads (Pure) -
Fast prediction of antibiotic permeability through membrane channels using Brownian dynamics
Acharya, A., Jana, K., Gurvic, D., Zachariae, U. & Kleinekathöfer, U. (Lead / Corresponding author), 25 Jul 2023, In: Biophysical Journal. 122, 14, p. 2996-3007 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)34 Downloads (Pure) -
2022
Data-driven derivation of molecular substructures that enhance drug activity in Gram-negative bacteria
Gurvic, D., Leach, A. G. & Zachariae, U. (Lead / Corresponding author), 28 Apr 2022, In: Journal of Medicinal Chemistry. 65, 8, p. 6088-6099 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)140 Downloads (Pure) -
2020
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
Alghamdi, A. H., Munday, J. C., Campagnaro, G. D., Gurvic, D., Svensson, F., Okpara, C. E., Kumar, A., Quintana, J. F., Abril, M. E. M., Milić, P., Watson, L., Paape, D., Settimo, L., Dimitriou, A., Wielinska, J., Smart, G., Anderson, L. F., Woodley, C. M., Kelley, S. P. Y. & Ibrahim, H. M. S. & 12 others, , 4 Sept 2020, In: eLife. 9, 33 p., e56416.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)135 Downloads (Pure)