Inhibition by Proxy Targeting Fungal Citin Synthesis through Sugar Nucleotide Biosynthesis (Clinical Postdoctoral Research Training Fellowship)

Lockhart, Deborah (Investigator)
van Aalten, Daan (Investigator)

Gene Regulation and Expression

Status	Finished
Effective start/end date	1/12/15 → 31/05/18

Funding

Wellcome Trust (105772/Z/14/Z): £208,270.02

3 Article

Genetic and structural validation of phosphomannomutase as a cell wall target in Aspergillus fumigatus
Zhang, Y., Fang, W., Raimi, O. G., Lockhart, D., Ferenbach, A. T., Lu, L. & van Aalten, D., Jul 2021, In: Molecular Microbiology. 116, 1, p. 245-259 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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5 Citations (Scopus)

64 Downloads (Pure)
The citron homology domain as a scaffold for Rho1 signaling
Bartual, S. G., Wei, W., Zhou, Y., Pravata, V. M., Fang, W., Yan, K., Ferenbach, A. T., Lockhart, D. E. A. & van Aalten, D. M. F., 28 Sept 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 39, 10 p., e2110298118.
Research output: Contribution to journal › Article › peer-review

Open Access
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3 Citations (Scopus)

36 Downloads (Pure)
Targeting a critical step in fungal hexosamine biosynthesis
Lockhart, D., Stanley, M., Raimi, O., Robinson, D., Boldovjakova, D., Squair, D., Ferenbach, A., Fang, W. & van Aalten, D., 26 Jun 2020, In: Journal of Biological Chemistry. 295, 26, p. 8678-8691 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
8 Citations (Scopus)

52 Downloads (Pure)