Research output per year
Research output per year
Research output
- 11 Article
- 11 results
Search results
-
2019
Are PARKIN patients ideal candidates for dopaminergic cell replacement therapies?
Kunath, T., Natalwala, A., Chan, C., Chen, Y., Stecher, B., Taylor, M., Khan, S. & Muqit, M. M. K., 25 Feb 2019, In: European Journal of Neuroscience. 49, 4, p. 453-462 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)169 Downloads (Pure) -
2018
Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
McWilliams, T. G., Prescott, A. R., Montava-Garriga, L., Ball, G., Singh, F., Barini, E., Muqit, M. M. K., Brooks, S. P. & Ganley, I. G., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 439-449.e5 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile356 Citations (Scopus)239 Downloads (Pure) -
Phosphorylation of Parkin at Serine65 is essential for its activation in vivo
McWilliams, T. G., Barini, E., Pohjolan-Pirhonen, R., Brooks, S. P., Singh, F., Burel, S., Balk, K., Kumar, A., Montava Garriga, L., Prescott, A., Hassoun, S. M., Mouton-Liger, F., Ball, G., Hills, R., Knebel, A., Ulusoy, A., Di Monte, D. A., Tamjar, J., Antico, O., Fears, K., & 11 others, Nov 2018, In: Open Biology. 8, 11, 18 p., 181108.Research output: Contribution to journal › Article › peer-review
Open AccessFile65 Citations (Scopus)226 Downloads (Pure) -
The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1
Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. & Muqit, M. M. K., 2 Mar 2018, In: ChemBioChem. 19, 5, p. 425-429 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)194 Downloads (Pure) -
2016
mito-QC illuminates mitophagy and mitochondrial architecture in vivo
McWilliams, T., Prescott, A., Allen, G., Tamjar, J., Munson, M., Thomson, C., Muqit, M. & Ganley, I., 25 Jul 2016, In: Journal of Cell Biology. 214, 3, p. 333-345 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile294 Citations (Scopus)391 Downloads (Pure) -
Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation
Pao, K. C., Stanley, M., Han, C., Lai, Y. C., Murphy, P., Balk, K., Wood, N. T., Corti, O., Corvol, J. C., Muqit, M. M. K. & Virdee, S., May 2016, In: Nature Chemical Biology. 12, 5, p. 324-331 8 p.Research output: Contribution to journal › Article › peer-review
79 Citations (Scopus) -
2015
A versatile strategy for the semisynthetic production of Ser65 phosphorylated ubiquitin and its biochemical and structural characterisation
Han, C., Pao, K-C., Kazlauskaite, A., Muqit, M. M. K. & Virdee, S., 27 Jul 2015, In: ChemBioChem. 16, 11, p. 1574-1579 6 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. MK., 1 Aug 2015, In: EMBO Reports. 16, 8, p. 939-954 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile155 Citations (Scopus)179 Downloads (Pure) -
Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog
Rogerson, D. T., Sachdeva, A., Wang, K., Haq, T., Kazlauskaite, A., Hancock, S. M., Huguenin-Dezot, N., Muqit, M. M. K., Fry, A. M., Bayliss, R. & Chin, J. W., Jul 2015, In: Nature Chemical Biology. 11, 7, p. 496-503 8 p.Research output: Contribution to journal › Article › peer-review
154 Citations (Scopus) -
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1
Lai, Y-C., Kondapalli, C., Lehneck, R., Procter, J. B., Dill, B. D., Woodroof, H. I., Gourlay, R., Peggie, M., Macartney, T. J., Corti, O., Corvol, J-C., Campbell, D. G., Itzen, A., Trost, M. & Muqit, M. MK., 12 Nov 2015, In: EMBO Journal. 34, 22, p. 2840-2861 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile130 Citations (Scopus)78 Downloads (Pure) -
PINK1 and Parkin - mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
Kazlauskaite, A. & Muqit, M. M. K., Jan 2015, In: FEBS Journal. 282, 2, p. 215-223 9 p.Research output: Contribution to journal › Article › peer-review
Open Access80 Citations (Scopus)