Research output per year
Research output per year
- 14 results
Search results
-
2023
Amino acid homeostasis is a target of metformin therapy
Forteath, C., Mordi, I., Nisr, R., Gutierrez-Lara, E. J., Alqurashi, N., Phair, I. R., Cameron, A. R., Beall, C., Nisr, I., Mohan, M., Wong, A. K. F., Dihoum, A., Mohammad, A., Palmer, C. N. A., Lamont, D., Sakamoto, K., Viollet, B., Foretz, M., Lang, C. C. & Rena, G., Aug 2023, In: Molecular Metabolism. 74, 16 p., 101750.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
2021
In a cohort of individuals with type 2 diabetes using the drug sulfasalazine, HbA1c lowering is associated with haematological changes
N'Dow, S. M. S., Donnelly, L. A., Pearson, E. R. & Rena, G., 16 Aug 2021, In: Diabetic Medicine. 38, 9, 9 p., e14463.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)69 Downloads (Pure) -
2018
Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology
Maack, C., Lehrke, M., Backs, J., Heinzel, F. R., Hulot, J-S., Marx, N., Paulus, W. J., Rossignol, P., Taegtmeyer, H., Bauersachs, J., Bayes-Genis, A., Brutsaert, D., Bugger, H., Clarke, K., Cosentino, F., De Keulenaer, G., Dei Cas, A., González, A., Huelsmann, M., Iaccarino, G., & 15 others, 21 Dec 2018, In: European Heart Journal. 39, 48, p. 4243-4254 12 p., ehy596.Research output: Contribution to journal › Article › peer-review
Open AccessFile157 Citations (Scopus)268 Downloads (Pure) -
Metformin selectively targets redox control of complex I energy transduction
Cameron, A., Logie, L., Patel, K., Erhardt, S., Bacon, S., Middleton, P., Harthill, J., Forteath, C., Coats, J., Kerr, C., Curry, H., Stewart, D., Sakamoto, K., Repiščák, P., Paterson, M. J., Hassinen, I., McDougall, G. & Rena, G., Apr 2018, In: Redox Biology. 14, p. 187-197 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile102 Citations (Scopus)201 Downloads (Pure) -
Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)
Logie, L., Lees, Z., Allwood, J. W., McDougall, G., Beall, C. & Rena, G., Dec 2018, In: Diabetes, Obesity & Metabolism. 20, 12, p. 2748-2758 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)201 Downloads (Pure) -
Repurposing metformin for cardiovascular disease
Rena, G. & Lang, C. C., 30 Jan 2018, In: Circulation. 137, 5, p. 422-424 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile84 Citations (Scopus)408 Downloads (Pure) -
2017
New Evidence for the Mechanism of Action of a Type-2 Diabetes Drug Using a Magnetic Bead-Based Automated Biosensing Platform
Uddin, R., Nur-E-Habiba, Rena, G., Hwu, E-T. & Boisen, A., 4 Aug 2017, In: ACS Sensors. 2, 9, p. 1329-1336 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)207 Downloads (Pure) -
The mechanisms of action of metformin
Rena, G., Hardie, D. G. & Pearson, E. R., Sept 2017, In: Diabetologia. 60, 9, p. 1577-1585 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1228 Citations (Scopus)421 Downloads (Pure) -
2016
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Cameron, A. R., Morrison, V., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, K., Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G., 19 Aug 2016, In: Circulation Research. 119, 5, p. 652-665 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile430 Citations (Scopus)350 Downloads (Pure) -
Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug
Cameron, A., Logie, L., Patel, K., Bacon, S., Forteath, C., Harthill, J., Roberts, A., Sutherland, C., Stewart, D., Viollet, B., Sakamoto, K., McDougall, G., Foretz, M. & Rena, G., Aug 2016, In: BBA - Molecular Basis of Disease. 1862, 8, p. 1412-1422 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)1130 Downloads (Pure) -
2015
The copper binding properties of metformin - QCM-D, XPS and nanobead agglomeration
Quan, X., Uddin, R., Heiskanen, A., Parmvi, M., Nilson, K., Donolato, M., Hansen, M. F., Rena, G. & Boisen, A., 18 Dec 2015, In: Chemical Communications. 51, 97, p. 17313-17316 4 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
2014
Biomolecular mode of action of metformin in relation to its copper binding properties
Repiščák, P., Erhardt, S., Rena, G. & Paterson, M. J., 4 Feb 2014, In: Biochemistry. 53, 4, p. 787-795 9 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
Salicylic acid: old and new implications for the treatment of type 2 diabetes?
Rena, G. & Sakamoto, K., Dec 2014, In: Diabetology International. 5, 4, p. 212-218 7 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
2013
Molecular mechanism of action of metformin: old or new insights?
Rena, G., Pearson, E. R. & Sakamoto, K., Sept 2013, In: Diabetologia. 56, 9, p. 1898-1906 9 p.Research output: Contribution to journal › Article › peer-review
361 Citations (Scopus)