Research output per year
Research output per year
- 13 results
Search results
-
2023
Amino acid homeostasis is a target of metformin therapy
Forteath, C., Mordi, I., Nisr, R., Gutierrez-Lara, E. J., Alqurashi, N., Phair, I. R., Cameron, A. R., Beall, C., Nisr, I., Mohan, M., Wong, A. K. F., Dihoum, A., Mohammad, A., Palmer, C. N. A., Lamont, D., Sakamoto, K., Viollet, B., Foretz, M., Lang, C. C. (Lead / Corresponding author) & Rena, G. (Lead / Corresponding author), Aug 2023, In: Molecular Metabolism. 74, 16 p., 101750.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)71 Downloads (Pure) -
2021
In a cohort of individuals with type 2 diabetes using the drug sulfasalazine, HbA1c lowering is associated with haematological changes
N'Dow, S. M. S., Donnelly, L. A., Pearson, E. R. & Rena, G. (Lead / Corresponding author), 16 Aug 2021, In: Diabetic Medicine. 38, 9, 9 p., e14463.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)140 Downloads (Pure) -
2018
Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology
Maack, C., Lehrke, M., Backs, J., Heinzel, F. R., Hulot, J.-S., Marx, N., Paulus, W. J., Rossignol, P., Taegtmeyer, H., Bauersachs, J., Bayes-Genis, A., Brutsaert, D., Bugger, H., Clarke, K., Cosentino, F., De Keulenaer, G., Dei Cas, A., González, A., Huelsmann, M. & Iaccarino, G. & 15 others, , 21 Dec 2018, In: European Heart Journal. 39, 48, p. 4243-4254 12 p., ehy596.Research output: Contribution to journal › Article › peer-review
Open AccessFile186 Citations (Scopus)329 Downloads (Pure) -
Metformin selectively targets redox control of complex I energy transduction
Cameron, A., Logie, L., Patel, K., Erhardt, S., Bacon, S., Middleton, P., Harthill, J., Forteath, C., Coats, J., Kerr, C., Curry, H., Stewart, D., Sakamoto, K., Repiščák, P., Paterson, M. J., Hassinen, I., McDougall, G. & Rena, G. (Lead / Corresponding author), Apr 2018, In: Redox Biology. 14, p. 187-197 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile115 Citations (Scopus)248 Downloads (Pure) -
Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)
Logie, L., Lees, Z., Allwood, J. W., McDougall, G., Beall, C. (Lead / Corresponding author) & Rena, G. (Lead / Corresponding author), Dec 2018, In: Diabetes, Obesity & Metabolism. 20, 12, p. 2748-2758 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)217 Downloads (Pure) -
Repurposing metformin for cardiovascular disease
Rena, G. (Lead / Corresponding author) & Lang, C. C. (Lead / Corresponding author), 30 Jan 2018, In: Circulation. 137, 5, p. 422-424 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile103 Citations (Scopus)500 Downloads (Pure) -
2017
New Evidence for the Mechanism of Action of a Type-2 Diabetes Drug Using a Magnetic Bead-Based Automated Biosensing Platform
Uddin, R., Nur-E-Habiba, Rena, G., Hwu, E.-T. & Boisen, A., 4 Aug 2017, In: ACS Sensors. 2, 9, p. 1329-1336 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)226 Downloads (Pure) -
2016
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Cameron, A. R., Morrison, V., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, K., Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G. (Lead / Corresponding author), 19 Aug 2016, In: Circulation Research. 119, 5, p. 652-665 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile491 Citations (Scopus)415 Downloads (Pure) -
Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug
Cameron, A., Logie, L., Patel, K., Bacon, S., Forteath, C., Harthill, J., Roberts, A., Sutherland, C., Stewart, D., Viollet, B., Sakamoto, K., McDougall, G., Foretz, M. & Rena, G., Aug 2016, In: BBA - Molecular Basis of Disease. 1862, 8, p. 1412-1422 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)1170 Downloads (Pure) -
2015
The copper binding properties of metformin - QCM-D, XPS and nanobead agglomeration
Quan, X. (Lead / Corresponding author), Uddin, R., Heiskanen, A., Parmvi, M., Nilson, K., Donolato, M., Hansen, M. F., Rena, G. & Boisen, A. (Lead / Corresponding author), 18 Dec 2015, In: Chemical Communications. 51, 97, p. 17313-17316 4 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
2014
Biomolecular mode of action of metformin in relation to its copper binding properties
Repiščák, P., Erhardt, S., Rena, G. & Paterson, M. J. (Lead / Corresponding author), 4 Feb 2014, In: Biochemistry. 53, 4, p. 787-795 9 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
Salicylic acid: old and new implications for the treatment of type 2 diabetes?
Rena, G. (Lead / Corresponding author) & Sakamoto, K. (Lead / Corresponding author), Dec 2014, In: Diabetology International. 5, 4, p. 212-218 7 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
2013
Molecular mechanism of action of metformin: old or new insights?
Rena, G. (Lead / Corresponding author), Pearson, E. R. & Sakamoto, K. (Lead / Corresponding author), Sept 2013, In: Diabetologia. 56, 9, p. 1898-1906 9 p.Research output: Contribution to journal › Article › peer-review
382 Citations (Scopus)