Research output per year
Research output per year
Search results
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2024
The search for CDK4/6 inhibitor biomarkers has been hampered by inappropriate proliferation assays
Foy, R. (Lead / Corresponding author), Lew, K. X. & Saurin, A. T. (Lead / Corresponding author), 4 Mar 2024, In: NPJ Breast Cancer. 10, 11 p., 19.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Link opens in a new tab Citations (Scopus)176 Downloads (Pure) -
2023
A bifunctional kinase–phosphatase module balances mitotic checkpoint strength and kinetochore–microtubule attachment stability
Corno, A., Cordeiro, M. H., Allan, L. A., Lim, Q. W., Harrington, E., Smith, R. J. & Saurin, A. T., 16 Oct 2023, In: EMBO Journal. 42, 20, 22 p., e112630.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Link opens in a new tab Citations (Scopus)193 Downloads (Pure) -
CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence
Crozier, L., Foy, R., Adib, R., Kar, A., Holt, J. A., Pareri, A. U., Valverde, J. M., Rivera, R., Weston, W. A., Wilson, R., Regnault, C., Whitfield, P., Badonyi, M., Bennett, L. G., Vernon, E. G., Gamble, A., Marsh, J. A., Staples, C. J., Saurin, A. T. & Barr, A. R. & 1 others, , 16 Nov 2023, In: Molecular Cell. 83, 22, p. 4062-4077.e5 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Link opens in a new tab Citations (Scopus)230 Downloads (Pure) -
Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest
Foy, R., Crozier, L., Pareri, A. U., Valverde, J. M., Ho Park, B., Ly, T. & Saurin, A. T. (Lead / Corresponding author), 16 Nov 2023, In: Molecular Cell. 83, 22, p. 4047-4061.e6 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile44 Link opens in a new tab Citations (Scopus)234 Downloads (Pure) -
2022
CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal
Crozier, L., Foy, R., Mouery, B. L., Whitaker, R. H., Corno, A., Spanos, C., Ly, T., Cook, J. G. & Saurin, A. (Lead / Corresponding author), 15 Mar 2022, In: EMBO Journal. 41, 6, 20 p., e108599.Research output: Contribution to journal › Article › peer-review
Open AccessFile99 Link opens in a new tab Citations (Scopus)813 Downloads (Pure) -
2020
Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint
Allan, L. A., Reis, M. C., Ciossani, G., Huigs in ‘t Veld, P. J., Wohlgemuth, S., Kops, G. J. P. L., Musacchio, A. & Saurin, A. T. (Lead / Corresponding author), 17 Jun 2020, In: EMBO Journal. 39, 12, 16 p., e103180.Research output: Contribution to journal › Article › peer-review
Open AccessFile61 Link opens in a new tab Citations (Scopus)349 Downloads (Pure) -
Kinetochore phosphatases suppress autonomous Polo-like kinase 1 activity to control the mitotic checkpoint
Cordeiro, M. H. (Lead / Corresponding author), Smith, R. J. & Saurin, A. T. (Lead / Corresponding author), 7 Dec 2020, In: Journal of Cell Biology. 219, 12, 27 p., e202002020.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Link opens in a new tab Citations (Scopus)236 Downloads (Pure) -
2019
Division of labour between PP2A-B56 isoforms at the centromere and kinetochore
Vallardi, G., Allan, L., Crozier, L. & Saurin, A. T. (Lead / Corresponding author), 4 Mar 2019, In: eLife. 8, p. 1-25 25 p., e42619.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Link opens in a new tab Citations (Scopus)343 Downloads (Pure) -
PP1 and PP2A use opposite phospho-dependencies to control distinct processes at the kinetochore
Smith, R., Henriques Cordeiro, M., Davey, N. E., Vallardi, G., Ciliberto, A., Gross, F. & Saurin, A. (Lead / Corresponding author), 20 Aug 2019, In: Cell Reports. 28, 8, p. 2206-2219.e8 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Link opens in a new tab Citations (Scopus)268 Downloads (Pure)