Leucine and ACE Inhibitors as Therapies for Sarcopenia; a Two by Two Factorial Randomised Placebo Controlled Trial (Joint with NHS Tayside, Imperial College London and University of Aberdeen)

Donnan, Peter (Investigator)
George, Jacob (Investigator)
McMurdo, Marion (Investigator)
Struthers, Allan (Investigator)
Sumukadas, Deepa (Investigator)
Witham, Miles (Investigator)

4 Article
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2024
Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: Findings from the LACE sarcopenia trial
Shrestha, A. (Lead / Corresponding author), Bashir, T., Achison, M., Adamson, S., Akpan, A., Aspray, T., Avenell, A., Band, M. M., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Hume, C., Jackson, T. A., Kerr, S. & Kilgour, A. & 16 others, Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Sayer, A. A., Rossios, C., Smith, K., Soiza, R. L., Steves, C. J., Struthers, A., Tiwari, D., Whitney, J., Witham, M. D. & Kemp, P. R., 2 Aug 2024, In: PLoS ONE. 19, 8, 14 p., e0307268.
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2023
Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia – analyses from the LACE randomised controlled trial
Bashir, T., Achison, M., Adamson, S., Akpan, A., Aspray, T., Avenell, A., Band, M. M., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Hume, C., Jackson, T. A., Kerr, S., Kilgour, A. & Masud, T. & 15 others, McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Rossios, C., Sayer, A. A., Smith, K. T., Soiza, R. L., Steves, C. J., Struthers, A. D., Tiwari, D., Whitney, J., Witham, M. D. & Kemp, P. R. (Lead / Corresponding author), 14 Nov 2023, In: PLoS ONE. 18, 11, 18 p., e0294330.
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2022
Effect of Perindopril or Leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial
LACE study group, Achison, M., Adamson, S., Akpan, A., Aspray, T., Avenell, A., Band, M. M., Bashir, T., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Henderson, E., Hume, C., Jackson, T. A. & Kemp, P. & 19 others, Kerr, S., Kilgour, A., Lyell, V., Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Rossios, C., Sayer, A. A., Smith, K. T., Soiza, R. L., Steves, C. J., Struthers, A. D., Sumukadas, D., Tiwari, D., Whitney, J. & Witham, M. D. (Lead / Corresponding author), 4 Apr 2022, In: Journal of Cachexia, Sarcopenia and Muscle. 13, 2, p. 858-871 14 p.
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Leucine and perindopril to improve physical performance in people over 70 years with sarcopenia: the LACE factorial RCT
Witham, M., Adamson, S., Avenell, A., Band, M., Bashir, T., Donnan, P., George, J., Hapca, A., Hume, C., Kemp, P. R., McKenzie, E., Pilvinyte, K., Rossios, C., Smith, K., Struthers, A. & Sumukadas, D., Aug 2022, In: Efficacy and Mechanism Evaluation. 9, 8, 108 p.
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Leucine and ACE Inhibitors as Therapies for Sarcopenia; a Two by Two Factorial Randomised Placebo Controlled Trial (Joint with NHS Tayside, Imperial College London and University of Aberdeen)

Research output

Search results

Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: Findings from the LACE sarcopenia trial

Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia – analyses from the LACE randomised controlled trial

Effect of Perindopril or Leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial

Leucine and perindopril to improve physical performance in people over 70 years with sarcopenia: the LACE factorial RCT