Keyphrases
Interleukin-6
87%
Glycoprotein 130 (gp130)
62%
Cytokine Signaling
62%
Interleukin-27 (IL-27)
55%
Structural Insights
55%
Functional Pleiotropy
42%
Cytokine Response
37%
Phosphoproteomics
37%
Th1 Cells
34%
Mutein
27%
Signaling Signature
27%
Resident Time
27%
IL6ST
27%
Gene Locus
27%
Interleukin-11 (IL-11)
27%
CDK8
27%
Signaling Complex
27%
Transcriptional Activity
27%
Receptor Trafficking
27%
Tumor
27%
Proteomic Analysis
27%
Molecular Factors
27%
Functional Selectivity
27%
Acidic pH
27%
Immunodeficiency
27%
Competitive Binding
27%
Cytokine Receptor
27%
Interleukin-2
27%
Cellular Factors
27%
Receptor Binding
20%
Functional Diversity
18%
Janus Kinase
18%
T Helper 17 (Th17)
16%
Endosomal Compartment
16%
Receptor Recognition
13%
SILAC
13%
Cell Surface Receptor
13%
Signaling Network
13%
Phosphopeptides
13%
Dwell Time
13%
High-resolution
13%
Soluble interleukin-2 Receptor (sIL-2R)
13%
Amino Acids-based
13%
Protocol Optimization
13%
Extracellular Space
13%
CD8+ T Cells
13%
Pleiotropic Effects
12%
Signaling Pathway
12%
Gene Expression Programming
12%
Immune Response
11%
STAT1 Phosphorylation
10%
Cryogenic Electron Microscopy
10%
STAT3 Phosphorylation
10%
Receptor Binding Affinity
9%
Less Toxic
9%
Cell Subsets
9%
Transcriptional Repressor
9%
Signal Transducer
9%
Kinase Protein
9%
Specific Genes
9%
Protein Level
9%
Receptor Dimerization
9%
Oligomerization
9%
Shared Use
9%
Soluble Factors
9%
STAT Activation
9%
Ligand-receptor Binding
9%
First-principles
9%
Toxic Response
9%
Protein Engineering
9%
Cytokine Stimulation
9%
STAT Proteins
9%
Functional Response
9%
Intracellular Domain
9%
Common Mechanisms
9%
High-dose interleukin-2
6%
EBI3
6%
Biased Signaling
6%
IL-27Rα
6%
Dimmer Switch
6%
Binding Core
6%
IL-11 Receptor
6%
Chromatin
6%
Unique Pattern
6%
Molecular Understanding
6%
Neutral pH
6%
Signal Switching
6%
Lactic Acid
6%
Cryo-EM Structure
6%
Disease Variants
6%
Biological Outcomes
6%
Mode of Action
6%
Influence Functional
6%
High Dose
6%
Gene Response
6%
Phosphotyrosine
6%
Tumor Immunity
6%
Acidic Environment
6%
T Cell Immunity
6%
Effector Function
6%
Immune Deficiency
6%
Binding Interface
6%
Extracellular Domain
6%
Gene Expression Differences
6%
Binding Parameters
6%
Differential Signaling
6%
Immune Activation
6%
Receptor Subunits
6%
Cellular Response
6%
Directed Evolution
6%
Human Disease
6%
Mode Switch
6%
Transmembrane Helix
6%
Regulatory T (Treg) Cells
6%
High Affinity
6%
Physicochemical Properties
6%
Molecular Dynamics Simulation
6%
Tumor Rejection
6%
Effector Differentiation
6%
Off-target Toxicity
6%
Mutant Forms
6%
Biochemistry, Genetics and Molecular Biology
Cytokine
100%
Interleukin 6
79%
STAT3
60%
Pleiotropy
42%
STAT1
41%
Cytokine Response
30%
Gene Locus
27%
Cytokine Receptor
27%
Interleukin 27
27%
Binding Competition
27%
Proteomics
27%
Receptor Binding
23%
Phosphoproteomics
17%
Dwell Time
13%
Isotope Labeling
13%
Amino Acids
13%
Phosphopeptide
13%
Gene Expression
13%
Janus Kinase
8%
Regulatory T Cell
6%
Cell Surface Receptor
6%
EBI3
6%
Tyrosine
6%
Immunology and Microbiology
Cytokine
80%
Glycoprotein Gp 130
42%
Interleukin 6
37%
Pleiotropy
31%
Cytokine Response
31%
Interleukin 27
27%
Interleukin 2
27%
Binding Competition
27%
STAT1
27%
Interleukin 11
27%
Immunodeficiency
27%
Cryo-Electron Microscopy
17%
Cytokine Signaling
16%
STAT3
11%
STAT5
11%
Drug Megadose
11%
Cytotoxic T-Cell
11%
Extracellular Space
11%
Immunotherapy
9%
Systemic Lupus Erythematosus
7%
Gene Expression
7%
Immunodeficiency
6%
Cell Surface
6%
Motion
6%
Lactic Acid
5%
Interleukin 2 Receptor
5%
Immune Response
5%
Adoptive Immunity
5%
Tumor Rejection
5%