MASTER MIND - MRC ABPI Stratification and Extreme Response Mechanism in Type 2 Diabetes (Joint with University of Exeter, Newcastle University, Kings College London, University of Oxford and University of Glasgow)

Morris, Andrew (Investigator)
Palmer, Colin (Investigator)
Pearson, Ewan (Investigator)

11 results

2026
Precision medicine in type 2 diabetes: targeting SGLT2 inhibitor treatment for kidney protection
Jansz, T. T. (Lead / Corresponding author), Young, K. G., Hopkins, R., McGovern, A. P., Shields, B. M., Hattersley, A. T., Jones, A. G., Pearson, E. R., Bingham, C., Oram, R. A., Dennis, J. M. & on behalf of the MASTERMIND Consortium, Feb 2026, In: Diabetologia. 69, p. 374-385 12 p.
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2025
A five-drug class model using routinely available clinical features to optimise prescribing in type 2 diabetes: a prediction model development and validation study
Dennis, J. M. (Lead / Corresponding author), Young, K. G., Cardoso, P., Güdemann, L. M., McGovern, A. P., Farmer, A., Holman, R. R., Sattar, N., McKinley, T. J., Pearson, E. R., Jones, A. G., Shields, B. M. & Hattersley, A. T., Mar 2025, In: The Lancet. 405, 10480, p. 701-714 14 p.
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Evaluating prediction of short-term tolerability of five type 2 diabetes drug classes using routine clinical features: UK population-based study
Cardoso, P. (Lead / Corresponding author), Young, K. G., Hopkins, R., Mateen, B., Pearson, E., Hattersley, A., McKinley, T., Shields, B., Dennis, J. M. & the MASTERMIND consortium, Aug 2025, In: Diabetes, Obesity and Metabolism. 27, 8, p. 4320-4329 10 p.
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2024
Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes
Cardoso, P., Young, K. G., Nair, A. T. N., Hopkins, R., McGovern, A. P., Haider, E., Karunaratne, P., Donnelly, L., Mateen, B. A., Sattar, N., Holman, R. R., Bowden, J., Hattersley, A. T., Pearson, E. R., Jones, A. G., Shields, B. M., McKinley, T. J., Dennis, J. M. (Lead / Corresponding author) & MASTERMIND consortium, May 2024, In: Diabetologia. 67, 5, p. 822-836 15 p.
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Safety and effectiveness of SGLT2 inhibitors in a UK population with type 2 diabetes and aged over 70 years: an instrumental variable approach
Güdemann, L. M. (Lead / Corresponding author), Young, K. G., Thomas, N. J. M., Hopkins, R., Challen, R., Jones, A. G., Hattersley, A. T., Pearson, E. R., Shields, B. M., Bowden, J., Dennis, J. M., McGovern, A. P. & MASTERMIND consortium, Sept 2024, In: Diabetologia. 67, 9, p. 1817-1827 11 p.
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2023
Patient preference for second- and third-line therapies in type 2 diabetes: a prespecified secondary endpoint of the TriMaster study
Shields, B. M., Angwin, C. D., Shepherd, M. H., Britten, N., Jones, A. G., Sattar, N., Holman, R., Pearson, E. R. & Hattersley, A. T. (Lead / Corresponding author), Feb 2023, In: Nature Medicine. 29, p. 384–391 8 p.
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Patient stratification for determining optimal second-line and third-line therapy for type 2 diabetes: the TriMaster study
Shields, B. M., Dennis, J. M., Angwin, C. D., Warren, F., Henley, W. E., Farmer, A. J., Sattar, N., Holman, R. R., Jones, A. G., Pearson, E. R., Hattersley, A. T. (Lead / Corresponding author) & TriMaster Study group, Feb 2023, In: Nature Medicine. 29, p. 376–383 8 p.
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2020
Risk of anemia with metformin use in type 2 diabetes: A MASTERMIND study
Donnelly, L. A., Dennis, J. M., Coleman, R. L., Sattar, N., Hattersley, A. T., Holman, R. R. & Pearson, E. R. (Lead / Corresponding author), Oct 2020, In: Diabetes Care. 43, 10, p. 2493-2499 7 p.
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TriMaster: Randomised double-blind crossover study of a DPP4 inhibitor, SGLT2 inhibitor and thiazolidinedione as second-line or third-line therapy in patients with type 2 diabetes who have suboptimal glycaemic control on metformin treatment with or without a sulfonylurea - A MASTERMIND study protocol
Angwin, C., Jenkinson, C., Jones, A., Jennison, C., Henley, W., Farmer, A., Sattar, N., Holman, R. R., Pearson, E., Shields, B. (Lead / Corresponding author) & Hattersley, A., Dec 2020, In: BMJ Open. 10, 12, 10 p., e042784.
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2019
Time trends in prescribing of type 2 diabetes drugs, glycaemic response and risk factors: a retrospective analysis of primary care data, 2010-2017
Dennis, J. M., Henley, W. E., McGovern, A. P., Farmer, A. J., Sattar, N., Holman, R. R., Pearson, E. R., Hattersley, A. T., Shields, B. M. (Lead / Corresponding author), Jones, A. G. (Lead / Corresponding author) & MASTERMIND consortium, Jul 2019, In: Diabetes, Obesity & Metabolism. 21, 7, p. 1576-1584 9 p.
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What to do with diabetes therapies when HbA1c lowering is inadequate: add, switch, or continue? A MASTERMIND study
MASTERMIND consortium, McGovern, A. P. (Lead / Corresponding author), Dennis, J. M., Shields, B. M., Hattersley, A. T., Pearson, E. R. & Jones, A. G., 12 Apr 2019, In: BMC Medicine. 17, 1, p. 1-17 17 p., 79.
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MASTER MIND - MRC ABPI Stratification and Extreme Response Mechanism in Type 2 Diabetes (Joint with University of Exeter, Newcastle University, Kings College London, University of Oxford and University of Glasgow)

Research output

Search results

2026

2025

2024

2023

2020

2019