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Mechanism of Poly-SUMO Chain Recognition by the Ubiquitin Ligase RNF4 (joint with Imperial College London)
Hay, Ronald
(Investigator)
Molecular Cell and Developmental Biology
Overview
Fingerprint
Research Outputs
(2)
Project Details
Status
Finished
Effective start/end date
21/12/12
→
20/01/16
Funding
Biotechnology and Biological Sciences Research Council
(BB/J016004/1):
£312,711.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Ubiquitin
Biochemistry, Genetics and Molecular Biology
100%
RNF4
Keyphrases
75%
Small Ubiquitin-like Modifier
Keyphrases
50%
K63-linked Ubiquitin Chains
Keyphrases
50%
Ubiquitin-like
Keyphrases
50%
Structural Insights
Keyphrases
50%
Ubiquitin Ligase
Keyphrases
50%
Ubc13
Keyphrases
25%
Research output
Research output per year
2014
2014
2015
2015
2
Article
Research output per year
Research output per year
Structural basis for the RING catalyzed synthesis of K63 linked ubiquitin chains
Branigan, E.
,
Plechanovova, A.
, Jaffray, E. G., Naismith, J. H. (Lead / Corresponding author) &
Hay, R. T.
(Lead / Corresponding author),
Aug 2015
,
In:
Nature Structural & Molecular Biology.
22
,
8
,
p. 597-602
6 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Ubiquitin
100%
K63-linked Ubiquitin Chains
100%
Ubc13
50%
RNF4
50%
RING Domain
50%
85
Citations (Scopus)
208
Downloads (Pure)
Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4
Xu, Y.,
Plechanovová, A.
, Simpson, P., Marchant, J., Leidecker, O., Kraatz, S.,
Hay, R. T.
(Lead / Corresponding author) & Matthews, S. J. (Lead / Corresponding author),
27 Jun 2014
,
In:
Nature Communications.
5
,
12 p.
, 4217.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Ubiquitin-like
100%
Small Ubiquitin-like Modifier
100%
Structural Insights
100%
Ubiquitin Ligase
100%
RNF4
100%
32
Citations (Scopus)
292
Downloads (Pure)