Research output per year
Research output per year
Research output
- 8 Article
Search results
-
2021
A Conserved Mechanism for Regulating Replisome Disassembly in Eukaryotes
Jenkyn-Bedford, M., Jones, M. L., Baris, Y., Labib, K. P. M., Cannone, G., Yeeles, J. T. P. (Lead / Corresponding author) & Deegan, T. D. (Lead / Corresponding author), 23 Dec 2021, In: Nature. 600, p. 743-747 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile61 Citations (Scopus)527 Downloads (Pure) -
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease
Canal, B., McClure, A. W., Curran, J. F., Wu, M., Ulferts, R., Weissmann, F., Zeng, J., Bertolin, A. P., Milligan, J. C., Basu, S., Drury, L. S., Deegan, T. D., Fujisawa, R., Roberts, E. L., Basier, C., Labib, K., Beale, R., Howell, M. & Diffley, J. F. X. (Lead / Corresponding author), 2 Jul 2021, In: Biochemical Journal. 478, 13, p. 2445-2464 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)216 Downloads (Pure) -
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase
Basu, S. (Lead / Corresponding author), Mak, T. (Lead / Corresponding author), Ulferts, R., Wu, M., Deegan, T., Fujisawa, R., Tan, K. W., Lim, C. T., Basier, C., Canal, B., Curran, J. F., Drury, L. S., McClure, A. W., Roberts, E. L., Weissmann, F., Zeisner, T. U., Beale, R., Cowling, V. H., Howell, M. & Labib, K. & 1 others, , 2 Jul 2021, In: Biochemical Journal. 478, 13, p. 2481-2497 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)192 Downloads (Pure) -
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease
Canal, B., Fujisawa, R., McClure, A. W., Deegan, T. D., Wu, M., Ulferts, R., Weissmann, F., Drury, L. S., Bertolin, A. P., Zeng, J., Beale, R., Howell, M., Labib, K. & Diffley, J. F. X. (Lead / Corresponding author), 2 Jul 2021, In: Biochemical Journal. 478, 13, p. 2465-2479 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)202 Downloads (Pure) -
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease
Milligan, J. C., Zeisner, T. U., Papageorgiou, G., Joshi, D., Soudy, C., Ulferts, R., Wu, M., Lim, C. T., Tan, K. W., Weissmann, F., Canal, B., Fujisawa, R., Deegan, T., Nagaraj, H., Bineva-Todd, G., Basier, C., Curran, J. F., Howell, M., Beale, R. & Labib, K. & 2 others, , 2 Jul 2021, In: Biochemical Journal. 478, 13, p. 2499-2515 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)192 Downloads (Pure) -
TIMELESS-TIPIN and UBXN-3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans
Xia, Y., Fujisawa, R., Deegan, T. D., Sonneville, R. (Lead / Corresponding author) & Labib, K. (Lead / Corresponding author), 1 Sept 2021, In: The EMBO Journal. 40, 17, 18 p., e108053.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)178 Downloads (Pure) -
2020
CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold
Deegan, T. D. (Lead / Corresponding author), Mukherjee, P. P., Fujisawa, R., Polo Rivera, C. & Labib, K. P. M. (Lead / Corresponding author), 17 Aug 2020, In: eLife. 9, 33 p., e60371.Research output: Contribution to journal › Article › peer-review
Open AccessFile52 Citations (Scopus)179 Downloads (Pure) -
2019
Pif1-family helicases support fork convergence during DNA replication termination in eukaryotes
Deegan, T. (Lead / Corresponding author), Baxter, J., Ortiz Bazan, M., Yeeles, J. T. P. & Labib, K. (Lead / Corresponding author), 18 Apr 2019, In: Molecular Cell. 74, 2, p. 231-244.e9 24 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile61 Citations (Scopus)240 Downloads (Pure)