Molecular Mechanisms of O-GICNAC Signalling (Investigator award)

Project Details

StatusActive
Effective start/end date1/03/1631/08/21

Funding

  • Wellcome Trust (110061/Z/15/Z): £42,452.85
  • Wellcome Trust (110061/Z/15/Z): £1,527,933.00

Research Output

Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation

Gorelik, A., Galan Bartual, S., Borodkin, V., Varghese, J., Ferenbach, A. & van Aalten, D., Nov 2019, In : Nature Structural & Molecular Biology. 26, 11, p. 1071-1077 7 p.

Research output: Contribution to journalArticle

Open Access
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  • 3 Citations (Scopus)
    14 Downloads (Pure)

    Effects of hypo O-GlcNAcylation on Drosophila development

    Mariappa, D. N., Ferenbach, A. & van Aalten, D. M. F., 11 May 2018, In : Journal of Biological Chemistry. 293, 19, p. 7209-7221 13 p.

    Research output: Contribution to journalArticle

    Open Access
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  • 5 Citations (Scopus)
    117 Downloads (Pure)

    The conserved threonine-rich region of the HCF-1PRO repeat activates promiscuous OGT: UDP-GlcNAc glycosylation and proteolysis activities

    Kapuria, V., Röhrig, U. F., Waridel, P., Lammers, F., Borodkin, V. S., van Aalten, D. M. F., Zoete, V. & Herr, W., 16 Nov 2018, In : Journal of Biological Chemistry. 293, 46, p. 17754-17768 15 p.

    Research output: Contribution to journalArticle

    Open Access
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  • 131 Downloads (Pure)