Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 1/03/16 → 28/02/22 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being
Fingerprint
Datasets
-
Project PXD064425 Zscan4 as a candidate conveyor of early developmental defects in O-GlcNAc transferase intellectual disability
van Aalten, D. (Creator) & Pravata, V. (Creator), EMBL-EBI, 3 Oct 2025
https://www.ebi.ac.uk/pride/archive/projects/PXD064425
Dataset
-
Cryo-EM structure of O-GlcNAcase from Trichoplax Adhaerens
Hansen, S. B. (Creator), Galan Bartual, S. (Creator), Yuan, H. (Creator), Raimi, O. (Creator), Gorelik, A. (Creator), Ferenbach, A. T. (Creator), Lytje, K. (Creator), Pedersen, J. S. (Creator), Drace, T. (Creator), Boesen, T. (Creator) & van Aalten, D. (Creator), Electron Microscopy Data Bank, 17 Sept 2025
https://www.ebi.ac.uk/emdb/EMD-53082
Dataset
-
Cryo-EM structure of human O-GlcNAcase
Hansen, S. B. (Creator), Galan Bartual, S. (Creator), Yuan, H. (Creator), Raimi, O. (Creator), Gorelik, A. (Creator), Ferenbach, A. T. (Creator), Lytje, K. (Creator), Pedersen, J. S. (Creator), Drace, T. (Creator), Boesen, T. (Creator) & van Aalten, D. (Creator), Electron Microscopy Data Bank, 17 Sept 2025
https://www.ebi.ac.uk/emdb/EMD-53081
Dataset
-
Exploiting O-GlcNAc dyshomeostasis to screen O-GlcNAc transferase intellectual disability variants
Yuan, H., Mitchell, C. W., Ferenbach, A. T., Feresin, A., Benke, P. J., Tan, Q. K. & van Aalten, D., 14 Jan 2025, In: Stem Cell Reports. 20, 1, 13 p., 102380.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)32 Downloads (Pure) -
Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms
Hansen, S. B., Bartual, S. G., Yuan, H., Raimi, O. G., Gorelik, A., Ferenbach, A. T., Lytje, K., Pedersen, J. S., Drace, T., Boesen, T. & van Aalten, D. M. F. (Lead / Corresponding author), 3 Oct 2025, In: Nature Communications. 16, 14 p., 8828.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)27 Downloads (Pure) -
O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control
Mitchell, C. W., Yuan, H., Ferenbach, A. T., Sønderstrup-Jensen, M. & van Aalten, D. (Lead / Corresponding author), Jul 2025, In: Open Biology. 15, 7, 13 p., 250064.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)49 Downloads (Pure)