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New Players In The Targeted Degradation Of The PML-RARA Oncogene By Arsenic
Hay, Ronald
(Investigator)
Molecular Cell and Developmental Biology
Overview
Fingerprint
Research Outputs
(1)
Project Details
Status
Active
Effective start/end date
1/01/24
→
31/12/28
Funding
Cancer Research UK
(DRCRPG-May23/100003):
£1,636,242.68
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Target Molecule
Keyphrases
100%
Degrader
Keyphrases
100%
Ubiquitination
Biochemistry, Genetics and Molecular Biology
100%
SUMO2
Biochemistry, Genetics and Molecular Biology
100%
Promyelocytic Leukemia
Pharmacology, Toxicology and Pharmaceutical Science
100%
Bromodomain-containing Protein 4 (BRD4)
Keyphrases
75%
Ubiquitin
Biochemistry, Genetics and Molecular Biology
58%
Ubiquitin Ligase
Biochemistry, Genetics and Molecular Biology
58%
Research output
Research output per year
2024
2024
2024
1
Article
Research output per year
Research output per year
Mechanism of degrader-targeted protein ubiquitinability
Crowe, C.,
Nakasone, M.
, Chandler, S.,
Craigon, C.
,
Sathe, G.
,
Tatham, M.
, Makukhin, N.,
Hay, R.
&
Ciulli, A.
(Lead / Corresponding author),
11 Oct 2024
,
In:
Science Advances.
10
,
41
,
21 p.
, eado6492.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Target Molecule
100%
Degrader
100%
Ubiquitination
100%
Bromodomain-containing Protein 4 (BRD4)
75%
Lysine
50%
1
Citation (Scopus)
13
Downloads (Pure)