Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)

Ciulli, Alessio (Investigator)
Sapkota, Gopal (Investigator)

2 Article
1 Chapter (peer-reviewed)

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2021
Development of BromoTag: A “Bump-&-Hole”-PROTAC system to induce potent, rapid, and selective degradation of tagged target proteins
Bond, A. G., Craigon, C., Chan, K. H., Testa, A., Karapetsas, A., Fasimoye, R., Macartney, T., Blow, J. J., Alessi, D. R. & Ciulli, A. (Lead / Corresponding author), 28 Oct 2021, In: Journal of Medicinal Chemistry. 64, 20, p. 15477-15502 26 p.
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48 Citations (Scopus)

253 Downloads (Pure)
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma
Pietrobono, S. (Lead / Corresponding author), Gaudio, E., Gagliardi, S., Zitani, M., Carrassa, L., Migliorini, F., Petricci, E., Manetti, F., Makukhin, N., Bond, A. G., Paradise, B. D., Ciulli, A., Fernandez-Zapico, M. E., Bertoni, F. & Stecca, B. (Lead / Corresponding author), 3 Jun 2021, In: Oncogene. 40, p. 3799-3814 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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28 Citations (Scopus)

94 Downloads (Pure)