Physiological Studies of Sperm from Normal and Sub Fertile Men (joint with Universities of Birmingham and Durham)

Barratt, Christopher (Investigator)
Wilson, Stuart (Investigator)

Diabetes Endocrinology and Reproductive Biology

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2019
Novel pharmacological actions of Trequinsin Hydrochloride improve human sperm cell motility and function
McBrinn, R. C., Fraser, J., Hope, A. G., Gray, D. W., Barratt, C. L. R., Martins da Silva, S. J. (Lead / Corresponding author) & Brown, S. G. (Lead / Corresponding author), Dec 2019, In: British Journal of Pharmacology. 176, 23, p. 4521-4536 16 p.
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2018
Homozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacity
Brown, S. G., Miller, M. R., Lishko, P. V., Lester, D. H., Publicover, S. J., Barratt, C. L. R. (Lead / Corresponding author) & Martins Da Silva, S., 1 Oct 2018, In: Human Reproduction. 33, 10, p. 1812-1816 5 p.
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Single-cell analysis of [Ca2+]i signalling in sub-fertile men: characteristics and relation to fertilization outcome
Kelly, M. C., Brown, S. G., Costello, S. M., Ramalingam, M., Drew, E., Publicover, S. J., Barratt, C. L. R. (Lead / Corresponding author) & Martins Da Silva, S., Jun 2018, In: Human Reproduction. 33, 6, p. 1023-1033 11 p.
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2017
Complex CatSper-dependent and independent [Ca²⁺] signaling induced by human follicular fluid
Brown, S. G., Costello, S., Kelly, M., Ramalingam, M., Drew, E., Publicover, S. J., Barratt, C. (Lead / Corresponding author) & Martins Da Silva, S., 1 Oct 2017, In: Human Reproduction. 32, 10, p. 1995-2006 12 p.
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Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem
Martins Da Silva, S. J. (Lead / Corresponding author), Brown, S. G., Sutton, K., King, L. V., Ruso, H., Gray, D. W., Wyatt, P. G., Kelly, M. C., Barratt, C. L. R. & Hope, A. G., May 2017, In: Human Reproduction. 32, 5, p. 974-984 11 p.
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2016
A spontaneous increase in intracellular Ca²⁺ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K⁺ channels
Fernandes, G., Dasai, N., Kozlova, N., Mojadadi, A., Gall, M., Drew, E., Barratt, E., Madamidola, O. A., Brown, S. G., Milne, A. M., Martins Da Silva, S. J., Whalley, K. M., Barratt, C. L. R. & Jovanovic, A. (Lead / Corresponding author), Feb 2016, In: Human Reproduction. 31, 2, p. 287-297 11 p.
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Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF
Brown, S. G., Publicover, S. J., Mansell, S., Lishko, P. V., Williams, H. L., Ramalingam, M., Wilson, S. M., Barratt, C. L. R. (Lead / Corresponding author), Sutton, K. A. & Da Silva, S. M., 15 Jun 2016, In: Human Reproduction. 31, 6, p. 1147-1157 11 p.
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2015
Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa
Williams, H. L., Mansell, S., Alasmari, W., Brown, S. G., Wilson, S. M., Sutton, K. A., Miller, M. R., Lishko, P. V., Barratt, C. L. R. (Lead / Corresponding author), Publicover, S. J. & Martins da Silva, S., Dec 2015, In: Human Reproduction. 30, 12, p. 2737-2746 10 p.
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2014
Patch clamp studies of human sperm under physiological ionic conditions reveal three functionally and pharmacologically distinct cation channels
Mansell, S. A., Publicover, S. J., Barratt, C. L. R. & Wilson, S. M. (Lead / Corresponding author), May 2014, In: Molecular Human Reproduction. 20, 5, p. 392-408 17 p.
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2013
p,p'-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations
Tavares, R. S., Mansell, S., Barratt, C. L. R., Wilson, S. M., Publicover, S. J. & Ramalho-Santos, J., Dec 2013, In: Human Reproduction. 28, 12, p. 3167-3177 11 p.
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Physiological Studies of Sperm from Normal and Sub Fertile Men (joint with Universities of Birmingham and Durham)

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