PREDICTION-ADR: Personalisation of tREatment In Cardiovascular Disease Through Next Generation Sequencing - Adverse Drug Reactions (Joint with University of Uppsala, University of Liverpool and University of Utrecht)

Project Details

StatusFinished
Effective start/end date1/09/13 → 28/02/17

Funding

  • COMMISSION OF THE EUROPEAN COMMUNITIES (602108): £647,912.00
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Research Output

Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema

Maroteau, C., Siddiqui, M. K., Veluchamy, A., Carr, F., White, M., Cassidy, A. J., Rasmussen, E. R., Baranova, E. V., Eriksson, N., Bloch, K. M., Brown, N. J., Bygum, A., Hallberg, P., Karawajczyk, M., Magnusson, P. K. E., Yue, Q-Y., Syvänen, A-C., von Buchwald, C., Alfirevic, A., Maitland-van der Zee, A. H. & 3 others, Wadelius, M., Palmer, C. N. A. & PREDICTION-ADR Consortium, 4 Jun 2020, In : Clinical Pharmacology and Therapeutics. 8 p.

Research output: Contribution to journal › Article

Open Access

    • A common missense variant of LILRB5 is associated with statin intolerance and myalgia

    Siddiqui, M. K., Maroteau, C., Veluchamy, A., Tornio, A., Tavendale, R., Carr, F., Abelega, N-U., Carr, D., Bloch, K., Hallberg, P., Yue, Q-Y., Pearson, E. R., Colhoun, H., Morris, A. D., Dow, E., George, J., Pirmohamed, M., Ridker, P. M., Doney, A. S. F., Alfirevic, A. & 5 others, Wadelius, M., Maitland-van der Zee, A. H., Chasman, D. I., Palmer, C. N. A. & PREDICTION-ADR Consortium, 21 Dec 2017, In : European Heart Journal. 38, 48, p. 3569-3575 7 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 12 Citations (Scopus)
    146 Downloads (Pure)

    Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors

    Mahmoudpour, S. H., Veluchamy, A., Siddiqui, M. K., Asselbergs, F. W., Souverein, P. C., de Keyser, C. E., Hofman, A., Lang, C. C., Doney, A. S. F., Stricker, B. H., de Boer, A., Maitland-van der Zee, A-H., Palmer, C. N. A. & PREDICTION-ADR Consortium, Mar 2017, In : Pharmacogenetics and Genomics. 27, 3, p. 112-119 8 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 10 Citations (Scopus)
    137 Downloads (Pure)