PREDICTION-ADR: Personalisation of tREatment In Cardiovascular Disease Through Next Generation Sequencing - Adverse Drug Reactions (Joint with University of Uppsala, University of Liverpool and University of Utrecht)

Palmer, Colin (Investigator)

Population Health and Genomics

Status	Finished
Effective start/end date	1/09/13 → 28/02/17

Funding

COMMISSION OF THE EUROPEAN COMMUNITIES (602108): £647,912.00

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

SDG 3 Good Health and Well-being

A gene risk score using missense variants in SLCO1B1 is associated with earlier onset statin intolerance
Bigossi, M., Maroteau, C., Dawed, A. Y., Taylor, A., Srinivasan, S., Melhem, A. L., Pearson, E. R., Pola, R., Palmer, C. N. A. & Siddiqui, M. K. (Lead / Corresponding author), Sept 2023, In: European Heart Journal: Cardiovascular Pharmacotherapy. 9, 6, p. 536–545 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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11 Link opens in a new tab Citations (Scopus)

139 Downloads (Pure)
Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema
Maroteau, C. (Lead / Corresponding author), Siddiqui, M. K., Veluchamy, A., Carr, F., White, M., Cassidy, A. J., Rasmussen, E. R., Baranova, E. V., Eriksson, N., Bloch, K. M., Brown, N. J., Bygum, A., Hallberg, P., Karawajczyk, M., Magnusson, P. K. E., Yue, Q.-Y., Syvänen, A.-C., von Buchwald, C., Alfirevic, A. & Maitland-van der Zee, A. H. & 3 others, Wadelius, M., Palmer, C. N. A. & PREDICTION-ADR Consortium, Dec 2020, In: Clinical Pharmacology & Therapeutics. 108, 6, p. 1195-1202 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
19 Link opens in a new tab Citations (Scopus)

120 Downloads (Pure)
A common missense variant of LILRB₅ is associated with statin intolerance and myalgia
Siddiqui, M. K., Maroteau, C., Veluchamy, A., Tornio, A., Tavendale, R., Carr, F., Abelega, N.-U., Carr, D., Bloch, K., Hallberg, P., Yue, Q.-Y., Pearson, E. R., Colhoun, H., Morris, A. D., Dow, E., George, J., Pirmohamed, M., Ridker, P. M., Doney, A. S. F. & Alfirevic, A. & 5 others, Wadelius, M., Maitland-van der Zee, A. H., Chasman, D. I., Palmer, C. N. A. (Lead / Corresponding author) & PREDICTION-ADR Consortium, 21 Dec 2017, In: European Heart Journal. 38, 48, p. 3569-3575 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
44 Link opens in a new tab Citations (Scopus)

271 Downloads (Pure)

PREDICTION-ADR: Personalisation of tREatment In Cardiovascular Disease Through Next Generation Sequencing - Adverse Drug Reactions (Joint with University of Uppsala, University of Liverpool and University of Utrecht)

Project Details

Funding

UN Sustainable Development Goals

Fingerprint

A gene risk score using missense variants in SLCO1B1 is associated with earlier onset statin intolerance

Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema

A common missense variant of LILRB₅ is associated with statin intolerance and myalgia

PREDICTION-ADR: Personalisation of tREatment In Cardiovascular Disease Through Next Generation Sequencing - Adverse Drug Reactions (Joint with University of Uppsala, University of Liverpool and University of Utrecht)

Project Details

Funding

UN Sustainable Development Goals

Fingerprint

Research output

A gene risk score using missense variants in SLCO1B1 is associated with earlier onset statin intolerance

Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema

A common missense variant of LILRB5 is associated with statin intolerance and myalgia

A common missense variant of LILRB₅ is associated with statin intolerance and myalgia