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Preparing the Genome for Replication: Exploring the Consequences of Origin Licensing and Exploiting its Inhibition (Programme Grant)
Blow, Julian
(Investigator)
Overview
Fingerprint
Research Outputs
(3)
Project Details
Status
Finished
Effective start/end date
1/10/12
→
30/09/18
Funding
Cancer Research UK
(C303/A14301):
£1,384,027.31
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Licensure
Medicine & Life Sciences
100%
DNA Replication
Medicine & Life Sciences
69%
Genome Size
Medicine & Life Sciences
65%
G1 Phase
Medicine & Life Sciences
48%
Eukaryota
Medicine & Life Sciences
47%
S Phase
Medicine & Life Sciences
45%
Cell Division
Medicine & Life Sciences
43%
DNA
Medicine & Life Sciences
42%
Research output
Research output per year
2018
2018
2020
2021
2021
3
Article
Research output per year
Research output per year
The role of DDK and Treslin-MTBP in coordinating replication licensing and pre-Initiation Complex formation
Volpi, I.
,
Gillespie, P. J.
,
Chadha, G. S.
&
Blow, J.
,
Oct 2021
,
In:
Open Biology.
11
,
10
,
18 p.
, 210121.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Licensure
100%
S Phase
90%
Chromatin
81%
Proto-Oncogene Proteins c-mdm2
74%
Xenopus
48%
2
Citations (Scopus)
24
Downloads (Pure)
3 tera-basepairs as a fundamental limit for robust DNA replication
Al Mamun, M.
,
Albergante, L.
,
Blow, J. J.
&
Newman, T. J.
,
30 Jun 2020
,
In:
Physical Biology.
17
,
4
,
10 p.
, 046002.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Genome Size
100%
Eukaryota
72%
DNA Replication
70%
Cell Division
66%
Genome
47%
43
Downloads (Pure)
Lgr5+ intestinal stem cells reside in an unlicensed G1 phase
Carroll, T.
,
Newton, I.
,
Chen, Y.
,
Blow, J.
&
Nathke, I.
,
7 May 2018
,
In:
Journal of Cell Biology.
217
,
5
,
p. 1667-1685
19 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Licensure
100%
G1 Phase
96%
Stem Cells
67%
Epithelium
46%
Replication Origin
38%
22
Citations (Scopus)
158
Downloads (Pure)