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Purchase of Sample Handling Robot And Mass Spec For Structural Spectrometry Drug Screening

Project Details

StatusFinished
Effective start/end date1/06/21 → 31/05/22

Funding

  • Biotechnology and Biological Sciences Research Council (BB/V019635/1): £746,044.00

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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  • 2 Invited talk
  • 2 Oral presentation
  • 1 Participation in workshop, seminar, course
View all 5 activity

  • Investigating the conformational landscape of human histidine-rich glycoprotein using amide HDX-MS

    Hierons, S. J., Lin, B., Fritzen, R., Blindauer, C. A., Ajjan, R. A., Masson, G. R. (Lead / Corresponding author) & Stewart, A. J. (Lead / Corresponding author), Nov 2025, In: The Biochemical journal. 482, 22, p. 1721-1735 15 p., BCJ20253366.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    7 Downloads (Pure)

  • Structural Insights into allosteric inhibition of HRI kinase by heme binding via HDX-MS

    Kanta, S., Vinciauskaite, V., Neill, G., Muqit, M. & Masson, G. (Lead / Corresponding author), Jun 2025, In: Biochemical Journal. 482, 12, p. 859-875 17 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    3   Link opens in a new tab Citations (Scopus)
    61 Downloads (Pure)

  • WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2

    Wilson, J. C. J., Zhu, J. Y., Vinciauskaite, V., Lloyd, E. G., Lam, S., Hart, A., Goh, C. G., Bou-Dagher, F., Razumkov, H., Kobel, L., Kontarakis, Z., Fielden, J., Schlapansky, M. F., Loizou, J. I., Villunger, A., Corn, J. E., Biffi, G., Masson, G. R., Marciniak, S. J. & Bader, A. S. & 1 others, Jackson, S. P. (Lead / Corresponding author), Dec 2025, In: Nature Communications. 16, 1, 8983.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    19 Downloads (Pure)
View all 5 research outputs