RHAPSODY (Joint with 25 other parties)

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  • 2024

    An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study

    Slieker, R. C., Münch, M., Donnelly, L. A., Bouland, G. A., Dragan, I., Kuznetsov, D., Elders, P. J. M., Rutter, G. A., Ibberson, M., Pearson, E. R., 't Hart, L. M., van de Wiel, M. A. & Beulens, J. W. J. (Lead / Corresponding author), May 2024, In: Diabetologia. 67, 5, p. 885-894 10 p.

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  • Multi-omics subgroups associated with glycaemic deterioration in type 2 diabetes: an IMI-RHAPSODY Study

    Li, S., Dragan, I., Tran, V. D. T., Fung, C. H., Kuznetsov, D., Hansen, M. K., Beulens, J. W. J., 't Hart, L. M., Slieker, R. C., Donnelly, L. A., Gerl, M. J., Klose, C., Mehl, F., Simons, K., Elders, P. J. M., Pearson, E. R., Rutter, G. A. (Lead / Corresponding author) & Ibberson, M. (Lead / Corresponding author), 6 Mar 2024, In: Frontiers in endocrinology. 15, 9 p., 1350796.

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  • Trajectories of clinical characteristics, complications and treatment choices in data-driven subgroups of type 2 diabetes

    Li, X. (Lead / Corresponding author), Donnelly, L. A., Slieker, R. C., Beulens, J. W. J., ‘t Hart, L. M., Elders, P. J. M., Pearson, E. R., van Giessen, A., Leal, J. & Feenstra, T., Jul 2024, In: Diabetologia. 67, 7, p. 1343-1355 13 p.

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  • 2023

    Identification of biomarkers for glycaemic deterioration in type 2 diabetes

    Slieker, R. C., Donnelly, L. A., Akalestou, E., Lopez-Noriega, L., Melhem, R., Güneş, A., Abou Azar, F., Efanov, A., Georgiadou, E., Muniangi-Muhitu, H., Sheikh, M., Giordano, G. N., Åkerlund, M., Ahlqvist, E., Ali, A., Banasik, K., Brunak, S., Barovic, M., Bouland, G. A. & Burdet, F. & 46 others, Canouil, M., Dragan, I., Elders, P. J. M., Fernandez, C., Festa, A., Fitipaldi, H., Froguel, P., Gudmundsdottir, V., Gudnason, V., Gerl, M. J., van der Heijden, A. A., Jennings, L. L., Hansen, M. K., Kim, M., Leclerc, I., Klose, C., Kuznetsov, D., Mansour Aly, D., Mehl, F., Marek, D., Melander, O., Niknejad, A., Ottosson, F., Pavo, I., Duffin, K., Syed, S. K., Shaw, J. L., Cabrera, O., Pullen, T. J., Simons, K., Solimena, M., Suvitaival, T., Wretlind, A., Rossing, P., Lyssenko, V., Legido Quigley, C., Groop, L., Thorens, B., Franks, P. W., Lim, G. E., Estall, J., Ibberson, M., Beulens, J. W. J., 't Hart, L. M. (Lead / Corresponding author), Pearson, E. R. (Lead / Corresponding author) & Rutter, G. A. (Lead / Corresponding author), 3 May 2023, In: Nature Communications. 14, 18 p., 2533.

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  • Potential Value of Identifying Type 2 Diabetes Subgroups for Guiding Intensive Treatment: A Comparison of Novel Data-Driven Clustering With Risk-Driven Subgroups

    Li, X. (Lead / Corresponding author), van Giessen, A., Slieker, R. C., Beulens, J. W., Altunkaya, J., Pearson, E. R., Elders, P. J. M., Feenstra, T. L. & Leal, J., Jul 2023, In: Diabetes Care. 46, 7, p. 1395-1403 9 p.

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  • 2022

    Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

    IMI DIRECT Consortium, Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M.-G., Musholt, P. B., Kurbasic, A., De Masi, F., Tsirigos, K. & Pedersen, H. K. & 41 others, Gudmundsdottir, V., Thomas, C. E., Banasik, K., Jennison, C., Jones, A., Kennedy, G., Bell, J., Thomas, L., Frost, G., Thomsen, H., Allin, K., Hansen, T. H., Vestergaard, H., Hansen, T., Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Giordano, G. N., Froguel, P., Pavo, I., Ruetten, H., Pedersen, O., Dermitzakis, E. T., Franks, P. W., Schwenk, J. M., Adamski, J., Pearson, E. (Lead / Corresponding author), McCarthy, M. I. (Lead / Corresponding author) & Brunak, S. (Lead / Corresponding author), 18 Jan 2022, In: Cell Reports Medicine. 3, 1, 32 p., 100477.

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  • 2021

    Distinct molecular signatures of clinical clusters in people with type 2 diabetes: an IMI-RHAPSODY study

    Slieker, R. C., Donnelly, L. A., Fitipaldi, H., Bouland, G. A., Giordano, G. N., Åkerlund, M., Gerl, M. J., Ahlqvist, E., Ali, A., Dragan, L., Elders, P. J. M., Festa, A., Hansen, M. K., van der Heijden, A. A., Mansour Aly, D., Kim, M., Kuznetsov, D., Mehl, F., Klose, C. & Simons, K. & 15 others, Pavo, I., Pullen, T. J., Suvitaival, T., Wretlind, A., Rossing, P., Lyssenko, V., Legido-Quigley, C., Groop, L., Thorens, B., Franks, P. W., Ibberson, M., Rutter, G. A., Beulens, J. W. J., 't Hart, L. M. (Lead / Corresponding author) & Pearson, E. R. (Lead / Corresponding author), Nov 2021, In: Diabetes. 70, 11, p. 2683-2693 11 p.

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  • Elevated circulating follistatin associates with an increased risk of type 2 diabetes

    Wu, C., Borné, Y., Gao, R., López Rodriguez, M., Roell, W. C., Wilson, J. M., Regmi, A., Luan, C., Aly, D. M., Peter, A., Machann, J., Staiger, H., Fritsche, A., Birkenfeld, A. L., Tao, R., Wagner, R., Canouil, M., Hong, M. G., Schwenk, J. M. & Ahlqvist, E. & 22 others, Kaikkonen, M. U., Nilsson, P., Shore, A. C., Khan, F., Natali, A., Melander, O., Orho-Melander, M., Nilsson, J., Häring, H. U., Renström, E., Wollheim, C. B., Engström, G., Weng, J., Pearson, E. R., Franks, P. W., White, M. F., Duffin, K. L., Vaag, A. A., Laakso, M., Stefan, N., Groop, L. & De Marinis, Y. (Lead / Corresponding author), 10 Nov 2021, In: Nature Communications. 12, 10 p., 6486.

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  • Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study

    Slieker, R. C., Donnelly, L. A., Fitipaldi, H., Bouland, G. A., Giordano, G. N., Åkerlund, M., Gerl, M. J., Ahlqvist, E., Ali, A., Dragan, I., Festa, A., Hansen, M. K., Mansour Aly, D., Kim, M., Kuznetsov, D., Mehl, F., Klose, C., Simons, K., Pavo, I. & Pullen, T. J. & 13 others, Suvitaival, T., Wretlind, A., Rossing, P., Lyssenko, V., Legido-Quigley, C., Groop, L., Thorens, B., Franks, P. W., Ibberson, M., Rutter, G. A., Beulens, J. W. J., 't Hart, L. M. (Lead / Corresponding author) & Pearson, E. R. (Lead / Corresponding author), Sept 2021, In: Diabetologia. 64, p. 1982-1989 8 p.

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