Keyphrases
Leucine-rich Repeat Kinase 2 (LRRK2)
72%
Phosphorylation
69%
Parkin
54%
PTEN-induced Kinase 1 (PINK1)
36%
Parkinson's Disease
32%
E3 Ligase Activity
23%
Phosphorylated Ubiquitin
21%
Kinase Inhibitor
20%
Rab GTPase
19%
Ubiquitin
19%
Mitochondrial Membrane Potential
18%
Phos-tag
18%
Depolarization
18%
Rab10
18%
Phosphoproteomics
18%
Brain Penetrant
18%
LRRK2 Inhibitors
18%
Pyrrolopyrimidine
18%
Structural Characterization
18%
Kinase Function
18%
G2019S
13%
Therapeutic Target
10%
Ubiquitin-like
8%
LRRK2 Kinase Inhibitor
6%
Structural Optimization
6%
Saturation Transfer Difference NMR
6%
Co-crystal Structure
6%
Structure Function
6%
Kinase Inhibition
6%
NMR Spectroscopy
6%
Active Sites
6%
X-ray Crystallography
6%
Dictyostelium
6%
Drug Candidates
6%
Biochemistry, Genetics and Molecular Biology
Kinase
100%
Phosphotransferase
100%
Leucine-Rich Repeat
54%
Ubiquitin
36%
Serine
36%
Ubiquitin Ligase
26%
Phosphoproteomics
19%
LRRK2
18%
Mitochondrial Membrane Potential
18%
PINK1
18%
Wild Type
11%